Beneficial effects of the Mediterranean spices and aromas on non-alcoholic fatty liver disease

Abbasi Oshaghi, 2015, Lipid lowering effects of hydroalcoholic extract of anethum graveolens L. and dill tablet in high cholesterol fed hamsters, Cholesterol, 2015, 958560, 10.1155/2015/958560

Abenavoli, 2014, Alimentary regimen in non-alcoholic fatty liver disease: Mediterranean diet, World Journal of Gastroenterology, 20, 16831, 10.3748/wjg.v20.i45.16831

Abu-Shanab, 2010, The role of the gut microbiota in nonalcoholic fatty liver disease, Nature Reviews. Gastroenterology & Hepatology, 7, 691, 10.1038/nrgastro.2010.172

Acín, 2005, Dietary cholesterol suppresses the ability of olive oil to delay the development of atherosclerotic lesions in apolipoprotein E knockout mice, Atherosclerosis, 182, 17, 10.1016/j.atherosclerosis.2005.01.050

Acín, 2007, Olive oil preparation determines the atherosclerotic protection in apolipoprotein E knockout mice, The Journal of Nutritional Biochemistry, 18, 418, 10.1016/j.jnutbio.2006.08.005

Acín, 2007, Microarray analysis of hepatic genes differentially expressed in the presence of the unsaponifiable fraction of olive oil in apolipoprotein E-deficient mice, The British Journal of Nutrition, 97, 628, 10.1017/S0007114507657912

Adefegha, 2014, Antihyperglycemic, hypolipidemic, hepatoprotective and antioxidative effects of dietary clove (Szyzgium aromaticum) bud powder in a high-fat diet/streptozotocin-induced diabetes rat model, Journal of the Science of Food and Agriculture, 94, 2726, 10.1002/jsfa.6617

Afonso, 2013, Phenolic compounds from Rosemary (Rosmarinus officinalis L.) attenuate oxidative stress and reduce blood cholesterol concentrations in diet-induced hypercholesterolemic rats, Nutrition & Metabolism, 10, 19, 10.1186/1743-7075-10-19

Aguirre, 2014, Effects of resveratrol and other polyphenols in hepatic steatosis, World Journal of Gastroenterology, 20, 7366, 10.3748/wjg.v20.i23.7366

Ahn, 2013, Anti-obesity effects of glabridin-rich supercritical carbon dioxide extract of licorice in high-fat-fed obese mice, Food and Chemical Toxicology, 51, 439, 10.1016/j.fct.2012.08.048

Al-Okbi, 2014, Protective effect of clove oil and eugenol microemulsions on fatty liver and dyslipidemia as components of metabolic syndrome, Journal of Medicinal Food, 17, 764, 10.1089/jmf.2013.0033

Alavizadeh, 2014, Bioactivity assessment and toxicity of crocin: A comprehensive review, Food and Chemical Toxicology, 64, 65, 10.1016/j.fct.2013.11.016

de Almeida, 2007, Antigiardial activity of Ocimum basilicum essential oil, Parasitology Research, 101, 443, 10.1007/s00436-007-0502-2

Amrani, 2006, Hypolipidaemic activity of aqueous Ocimum basilicum extract in acute hyperlipidaemia induced by triton WR-1339 in rats and its antioxidant property, Phytotherapy Research, 20, 1040, 10.1002/ptr.1961

Anstee, 2011, How big a problem is non-alcoholic fatty liver disease?, British Medical Journal, 343, d3897, 10.1136/bmj.d3897

Anty, 2012, Regular coffee but not espresso drinking is protective against fibrosis in a cohort mainly composed of morbidly obese European women with NAFLD undergoing bariatric surgery, Journal of Hepatology, 57, 1090, 10.1016/j.jhep.2012.07.014

Arbones-Mainar, 2007, Extra virgin olive oils increase hepatic fat accumulation and hepatic antioxidant protein levels in APOE-/- mice, Journal of Proteome Research, 6, 4041, 10.1021/pr070321a

Asai, 2005, Orally administered crocetin and crocins are absorbed into blood plasma as crocetin and its glucuronide conjugates in mice, Journal of Agricultural and Food Chemistry, 53, 7302, 10.1021/jf0509355

Askari, 2014, Cinnamon may have therapeutic benefits on lipid profile, liver enzymes, insulin resistance, and high-sensitivity C-reactive protein in nonalcoholic fatty liver disease patients, Nutrition Research, 34, 143, 10.1016/j.nutres.2013.11.005

Assy, 2009, Olive oil consumption and non-alcoholic fatty liver disease, World Journal of Gastroenterology, 15, 1809, 10.3748/wjg.15.1809

d'Avila Farias, 2014, Eugenol derivatives as potential anti-oxidants: Is phenolic hydroxyl necessary to obtain an effect?, The Journal of Pharmacy and Pharmacology, 66, 733, 10.1111/jphp.12197

Awad, 2009, Bioassay-guided fractionation of lemon balm (Melissa officinalis L.) using an in vitro measure of GABA transaminase activity, Phytotherapy Research, 23, 1075, 10.1002/ptr.2712

Awe, 2013, Biochemical and haematological assessment of toxic effects of the leaf ethanol extract of Petroselinum crispum (Mill) Nyman ex A.W. Hill (Parsley) in rats, BMC Complementary and Alternative Medicine, 13, 75, 10.1186/1472-6882-13-75

Bach-Faig, 2011, Mediterranean diet pyramid today. Science and cultural updates, Public Health Nutrition, 14, 2274, 10.1017/S1368980011002515

Bahmani, 2016, Obesity Phytotherapy: Review of native herbs used in traditional medicine for obesity, Journal of Evidence-based Complementary & Alternative Medicine, 21, 228, 10.1177/2156587215599105

Bahmani, 2015, A review on promising natural agents effective on hyperlipidemia, Journal of Evidence-based Complementary & Alternative Medicine, 20, 228, 10.1177/2156587214568457

Bai, 2016, Protective effect of d-limonene against oxidative stress-induced cell damage in human lens epithelial cells via the p38 pathway, Oxidative Medicine and Cellular Longevity, 10.1155/2016/5962832

Bakhshaeshi, 2012, Anti-oxidative role of quercetin derived from Allium cepa on aldehyde oxidase (OX-LDL) and hepatocytes apoptosis in streptozotocin-induced diabetic rat, Asian Pacific Journal of Tropical Biomedicine, 2, 528, 10.1016/S2221-1691(12)60090-2

Barbalho, 2011, Metabolic profile of offspring from diabetic wistar rats treated with mentha piperita (peppermint), Evidence-Based Complementary and Alternative Medicine: eCAM, 2011, 430237, 10.1155/2011/430237

Barbaro, 2014, Effects of the olive-derived polyphenol oleuropein on human health, International Journal of Molecular Sciences, 15, 18508, 10.3390/ijms151018508

Barbosa-da-Silva, 2015, Singular effects of PPAR agonists on nonalcoholic fatty liver disease of diet-induced obese mice, Life Science, 127, 73, 10.1016/j.lfs.2015.02.003

Barroso, 2011, The PPARbeta/delta activator GW501516 prevents the down-regulation of AMPK caused by a high-fat diet in liver and amplifies the PGC-1alpha-Lipin 1-PPARalpha pathway leading to increased fatty acid oxidation, Endocrinology, 152, 1848, 10.1210/en.2010-1468

Behradmanesh, 2013, Effect of Salvia officinalis on diabetic patients, Journal of Renal Injury Prevention, 2, 51

Berlanga, 2014, Molecular pathways in non-alcoholic fatty liver disease, Journal of Clinical and Experimental Gastroenterology, 7, 221

Bolkent, 2005, Protective role of melissa officinalis L. extract on liver of hyperlipidemic rats: A morphological and biochemical study, Journal of Ethnopharmacology, 99, 391, 10.1016/j.jep.2005.02.038

Bolkent, 2004, Effects of parsley (Petroselinum crispum) on the liver of diabetic rats: A morphological and biochemical study, Phytotherapy Research, 18, 996, 10.1002/ptr.1598

Bower, 2015, The health benefits of selected culinary herbs and spices found in the traditional mediterranean diet, Critical Reviews in Food Science and Nutrition, 56, 2728, 10.1080/10408398.2013.805713

Bruce, 2009, The metabolic syndrome: Common origins of a multifactorial disorder, Postgraduate Medical Journal, 85, 614, 10.1136/pgmj.2008.078014

Cakir, 2016, Association between adherence to the mediterranean diet and presence of nonalcoholic fatty liver disease in children, Childhood Obesity, 12, 279, 10.1089/chi.2015.0197

Cani, 2012, Involvement of gut microbiota in the development of low-grade inflammation and type 2 diabetes associated with obesity, Gut Microbes, 3, 279, 10.4161/gmic.19625

Chalasani, 2012, The diagnosis and management of non-alcoholic fatty liver disease: Practice guideline by the american association for the study of liver diseases, american college of gastroenterology, and the american gastroenterological association, The American Journal of Gastroenterology, 107, 811, 10.1038/ajg.2012.128

Chithra, 1999, Coriandrum sativum changes the levels of lipid peroxides and activity of antioxidant enzymes in experimental animals, Indian Journal of Biochemistry & Biophysics, 36, 59

Cho, 2012, Carvacrol prevents diet-induced obesity by modulating gene expressions involved in adipogenesis and inflammation in mice fed with high-fat diet, The Journal of Nutritional Biochemistry, 23, 192, 10.1016/j.jnutbio.2010.11.016

Choi, 2013, Metabolic effects of aloe vera gel complex in obese prediabetes and early non-treated diabetic patients: Randomized controlled trial, Nutrition, 29, 1110, 10.1016/j.nut.2013.02.015

Cicerale, 2009, Chemistry and health of olive oil phenolics, Critical Reviews in Food Science and Nutrition, 49, 218, 10.1080/10408390701856223

Cicerale, 2010, Biological activities of phenolic compounds present in virgin olive oil, International Journal of Molecular Sciences, 11, 458, 10.3390/ijms11020458

Cortese, 2016, Carnosic acid induces proteasomal degradation of Cyclin B1, RB and SOX2 along with cell growth arrest and apoptosis in GBM cells, Phytomedicine, 23, 679, 10.1016/j.phymed.2016.03.007

Couturier, 2011, Cinnamon increases liver glycogen in an animal model of insulin resistance, Metabolism: Clinical and Experimental, 60, 1590, 10.1016/j.metabol.2011.03.016

Covas, 2006, The effect of polyphenols in olive oil on heart disease risk factors: A randomized trial, Annals of Internal Medicine, 145, 333, 10.7326/0003-4819-145-5-200609050-00006

Daher, 2006, Effect of Urtica dioica extract intake upon blood lipid profile in the rats, Fitoterapia, 77, 183, 10.1016/j.fitote.2006.01.010

Dal Rhee, 2012, Carbenoxolone prevents the development of fatty liver in C57BL/6-Lep ob/ob mice via the inhibition of sterol regulatory element binding protein-1c activity and apoptosis, European Journal of Pharmacology, 691, 9, 10.1016/j.ejphar.2012.06.021

Dallas, 2008, Lipolytic effect of a polyphenolic citrus dry extract of red orange, grapefruit, orange (SINETROL) in human body fat adipocytes. Mechanism of action by inhibition of cAMP-phosphodiesterase (PDE), Phytomedicine: International Journal of Phytotherapy and Phytopharmacology, 15, 783, 10.1016/j.phymed.2008.05.006

Davis, 2015, Definition of the mediterranean diet: A literature review, Nutrients, 7, 9139, 10.3390/nu7115459

De Minicis, 2013, From NAFLD to NASH and HCC: Pathogenetic mechanisms and therapeutic insights, Current Pharmaceutical Design, 19, 5239, 10.2174/1381612811319290006

Demori, 2016, Stress-related weight Gain: Mechanisms involving feeding behavior, metabolism, gut microbiota and inflammation, Journal of Nutrition & Food Sciences, 06, 1

Deng, 2004, Dietary olive oil and menhaden oil mitigate induction of lipogenesis in hyperinsulinemic corpulent JCR: La-cp rats: Microarray analysis of lipid-related gene expression, Endocrinology, 145, 5847, 10.1210/en.2004-0371

Dhuley, 1999, Anti-oxidant effects of cinnamon (Cinnamomum verum) bark and greater cardamom (Amomum subulatum) seeds in rats fed high fat diet, Indian Journal of Experimental Biology, 37, 238

Donnelly, 2005, Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease, The Journal of Clinical Investigation, 115, 1343, 10.1172/JCI23621

Dontas, 2007, Mediterranean diet and prevention of coronary heart disease in the elderly, Clinical Interventions in Aging, 2, 109, 10.2147/ciia.2007.2.1.109

Dufour, 2006, Randomized placebo-controlled trial of ursodeoxycholic acid with vitamin e in nonalcoholic steatohepatitis, Clinical Gastroenterology and Hepatology: The Official Clinical Practice Journal of the American Gastroenterological Association, 4, 1537, 10.1016/j.cgh.2006.09.025

El-Demerdash, 2005, Biochemical study on the hypoglycemic effects of onion and garlic in alloxan-induced diabetic rats, Food and Chemical Toxicology, 43, 57, 10.1016/j.fct.2004.08.012

Esposito, 2009, Probiotics reduce the inflammatory response induced by a high-fat diet in the liver of young rats, The Journal of Nutrition, 139, 905, 10.3945/jn.108.101808

Estruch, 2013, Primary prevention of cardiovascular disease with a Mediterranean diet, The New England Journal of Medicine, 368, 1279, 10.1056/NEJMoa1200303

Ezhumalai, 2015, Combination of carvacrol and rosiglitazone ameliorates high fat diet induced changes in lipids and inflammatory markers in C57BL/6J mice, Biochimie, 110, 129, 10.1016/j.biochi.2014.12.005

Fabbrini, 2008, Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease, Gastroenterology, 134, 424, 10.1053/j.gastro.2007.11.038

Faghihzadeh, 2015, Resveratrol and liver: A systematic review, Journal of Research in Medical Sciences: The Official Journal of Isfahan University of Medical Sciences, 20, 797, 10.4103/1735-1995.168405

Fan, 2013, Role of diet and nutritional management in non-alcoholic fatty liver disease, Journal of Gastroenterology and Hepatology, 28, 81, 10.1111/jgh.12244

Ferramosca, 2008, Olive oil increases the hepatic triacylglycerol content in mice by a distinct influence on the synthesis and oxidation of fatty acids, Bioscience, Biotechnology, and Biochemistry, 72, 62, 10.1271/bbb.70369

García-Vilas, 2013, 4-methylumbelliferone inhibits angiogenesis in vitro and in vivo, Journal of Agricultural and Food Chemistry, 61, 4063, 10.1021/jf303062h

Garcia, 2016, The effect of the traditional mediterranean-style diet on metabolic risk factors: A meta-analysis, Nutrients, 8, 168, 10.3390/nu8030168

Ghanbari, 2012, Valuable nutrients and functional bioactives in different parts of olive (Olea europaea L.)-a review, International Journal of Molecular Sciences, 13, 3291, 10.3390/ijms13033291

Gormez, 2015, Chemical composition and antibacterial activity of essential oils of two species of Lamiaceae against phytopathogenic bacteria, Polish Journal of Microbiology, 64, 121, 10.33073/pjm-2015-018

Grasselli, 2011, Direct effects of iodothyronines on excess fat storage in rat hepatocytes, Journal of Hepatology, 54, 1230, 10.1016/j.jhep.2010.09.027

Grasselli, 2014, 3,5-diiodo-L-thyronine modifies the lipid droplet composition in a model of hepatosteatosis, Cellular Physiology and Biochemistry, 33, 344, 10.1159/000356674

Grasselli, 2012, 3,5-Diiodo-L-thyronine modulates the expression of genes of lipid metabolism in a rat model of fatty liver, The Journal of Endocrinology, 212, 149, 10.1530/JOE-11-0288

Grasselli, 2016, Triglyceride mobilization from lipid droplets sustains the anti-steatotic action of iodothyronines in cultured rat hepatocytes, Frontiers in Physiology, 6, 1, 10.3389/fphys.2015.00418

Gray, 1997, Nature's own pharmacy: The diabetes perspective, The Proceedings of the Nutrition Society, 56, 507, 10.1079/PNS19970051

Gülçin, 2011, Antioxidant activity of eugenol: A structure-activity relationship study, Journal of Medicinal Food, 14, 975, 10.1089/jmf.2010.0197

Haidari, 2011, Effects of parsley (Petroselinum crispum) and its flavonol constituents, kaempferol and quercetin, on serum uric acid levels, biomarkers of oxidative stress and liver Xanthine oxidoreductase aactivity inOxonate-induced hyperuricemic rats, Iranian Journal of Pharmaceutical Research: IJPR, 10, 811

Hajhashemi, 2008, Hypolipidemic activity of Anethum graveolens in rats, Phytotherapy Research, 22, 372, 10.1002/ptr.2329

Hamaguchi, 2005, The metabolic syndrome as a predictor of nonalcoholic fatty liver disease, Annals of Internal Medicine, 143, 722, 10.7326/0003-4819-143-10-200511150-00009

Haque, 2014, Monoterpene phenolic compound thymol prevents high fat diet induced obesity in murine model, Toxicology Mechanisms and Methods, 24, 116, 10.3109/15376516.2013.861888

Harach, 2010, Rosemary (Rosmarinus officinalis L.) leaf extract limits weight gain and liver steatosis in mice fed a high-fat diet, Planta Medica, 76, 566, 10.1055/s-0029-1240612

Haramizu, 2011, Capsinoids, non-pungent capsaicin analogs, reduce body fat accumulation without weight rebound unlike dietary restriction in mice, Bioscience, Biotechnology and Biochemistry, 75, 95, 10.1271/bbb.100577

Harrison, 2003, Vitamin E and vitamin C treatment improves fibrosis in patients with nonalcoholic steatohepatitis, The American Journal of Gastroenterology, 98, 2485, 10.1111/j.1572-0241.2003.08699.x

Hauner, 2002, The mode of action of thiazolidinediones, Diabetes/metabolism Research and Reviews, 18, S10, 10.1002/dmrr.249

Helen, 2000, Antioxidant effect of onion oil (Allium cepa. Linn) on the damages induced by nicotine in rats as compared to alpha-tocopherol, Toxicology Letters, 116, 61, 10.1016/S0378-4274(00)00208-3

Hernández, 2005, Steatosis recovery after treatment with a balanced sunflower or olive oil-based diet: Involvement of perisinusoidal stellate cells, World Journal of Gastroenterology, 11, 7480, 10.3748/wjg.v11.i47.7480

Herrero, 2010, Green processes for the extraction of bioactives from Rosemary: Chemical and functional characterization via ultra-performance liquid chromatography-tandem mass spectrometry and in-vitro assays, Journal of Chromatography A, 1217, 2512, 10.1016/j.chroma.2009.11.032

Hoek-van den Hil, 2015, Direct comparison of metabolic health effects of the flavonoids quercetin, hesperetin, epicatechin, apigenin and anthocyanins in high-fat-diet-fed mice, Genes & Nutrition, 10, 469, 10.1007/s12263-015-0469-z

Hohmann, 1999, Protective effects of the aerial parts of Salvia officinalis, Melissa Officinalis and Lavandula angustifolia and their constituents against enzyme-dependent and enzyme-independent lipid peroxidation, Planta Medica, 65, 576, 10.1055/s-2006-960830

Hong, 2015, Capsinoids suppress fat accumulation via lipid metabolism, Molecular Medicine Reports, 11, 1669, 10.3892/mmr.2014.2996

Houghton, 2016, Gut microbiota and lifestyle interventions in NAFLD, International Journal of Molecular Sciences, 17, 447, 10.3390/ijms17040447

Hur, 2012, Oleuropein reduces free fatty acid-induced lipogenesis via lowered extracellular signal-regulated kinase activation in hepatocytes, Nutrition Research, 32, 778, 10.1016/j.nutres.2012.06.017

Ito, 2005, Antioxidant action of eugenol compounds: Role of metal ion in the inhibition of lipid peroxidation, Food and Chemical Toxicology, 43, 461, 10.1016/j.fct.2004.11.019

Jang, 2010, Inhibitory effects of ursolic acid on hepatic polyol pathway and glucose production in streptozotocin-induced diabetic mice, Metabolism: Clinical and Experimental, 59, 512, 10.1016/j.metabol.2009.07.040

Jia, 2015, Ursolic acid improves lipid and glucose metabolism in high-fat-fed C57BL/6J mice by activating peroxisome proliferator-activated receptor alpha and hepatic autophagy, Molecular Nutrition & Food Research, 59, 344, 10.1002/mnfr.201400399

Jing, 2013, Preventive and ameliorating effects of citrus D-limonene on dyslipidemia and hyperglycemia in mice with high-fat diet-induced obesity, European Journal of Pharmacology, 715, 46, 10.1016/j.ejphar.2013.06.022

Jung, 2012, Syzygium aromaticum ethanol extract reduces high-fat diet-induced obesity in mice through downregulation of adipogenic and lipogenic gene expression, Experimental and Therapeutic Medicine, 4, 409, 10.3892/etm.2012.609

Jung, 2011, Onion peel extracts ameliorate hyperglycemia and insulin resistance in high fat diet/streptozotocin-induced diabetic rats, Nutrition & Metabolism, 8, 18, 10.1186/1743-7075-8-18

Jun, 2012, Melissa officinalis essential oil reduces plasma triglycerides in human apolipoprotein E2 transgenic mice by inhibiting sterol regulatory element-binding protein-1c-dependent fatty acid synthesis, The Journal of Nutrition, 142, 432, 10.3945/jn.111.152538

Juurlink, 2009, Adverse cardiovascular events during treatment with pioglitazone and rosiglitazone: Population based cohort study, British Medical Journal, 339, b2942, 10.1136/bmj.b2942

Kaliora, 2005, Effect of Alkanna albugam root on LDL oxidation. A comparative study with species of the Lamiaceae family, Phytotherapy Research, 19, 1077, 10.1002/ptr.1774

Kamisoyama, 2008, Investigation of the anti-obesity action of licorice flavonoid oil in diet-induced obese rats, Bioscience, Biotechnology and Biochemistry, 72, 3225, 10.1271/bbb.80469

Kang, 2010, Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet, Obesity, 18, 780, 10.1038/oby.2009.301

Kang, 2007, Capsaicin, a spicy component of hot peppers, modulates adipokine gene expression and protein release from obese-mouse adipose tissues and isolated adipocytes, and suppresses the inflammatory responses of adipose tissue macrophages, FEBS Letters, 581, 4389, 10.1016/j.febslet.2007.07.082

Kastorini, 2011, The effect of mediterranean diet on metabolic syndrome and its components: A meta-analysis of 50 studies and 534,906 individuals, Journal of the American College of Cardiology, 57, 1299, 10.1016/j.jacc.2010.09.073

Kesavanarayanan, 2015, Herbal formulation, DIA-2 and Rosiglitazone ameliorates hyperglycemia and hepatic steatosis in type 2 diabetic rats, European Review for Medical and Pharmacological Sciences, 19, 3107

Keys, 1995, Mediterranean diet and public health: Personal reflections, The American Journal of Clinical Nutrition, 61, 1321S, 10.1093/ajcn/61.6.1321S

Kianbakht, 2011, Antihyperlipidemic effects of salvia officinalis L. leaf extract in patients with hyperlipidemia: A randomized double-blind placebo-controlled clinical trial, Phytotherapy Research, 25, 1849, 10.1002/ptr.3506

Kim, 2013, Carvacrol protects against hepatic steatosis in mice fed a high-fat diet by enhancing SIRT1-AMPK signaling, Evidence-Based Complementary and Alternative Medicine: eCAM, 2013, 290104

Kim, 2010, Hepatoprotective effect of oleuropein in mice: Mechanisms uncovered by gene expression profiling, Biotechnology Journal, 5, 950, 10.1002/biot.201000068

Kim, 2010, Antihyperglycemic and antihyperlipidemic action of Cinnamomi Cassiae (Cinnamon bark) extract in C57BL/Ks db/db mice, Archives of Pharmacal Research, 33, 325, 10.1007/s12272-010-0219-0

Kim, 2014, Oleuropein prevents the progression of steatohepatitis to hepatic fibrosis induced by a high-fat diet in mice, Experimental & Molecular Medicine, 46, e92, 10.1038/emm.2014.10

Kim, 2016, Inhibitory effects of Leonurus sibiricus on weight gain after menopause in ovariectomized and high-fat diet-fed mice, Journal of Natural Medicines, 70, 522, 10.1007/s11418-016-0971-7

Kim, 2013, Beneficial effects of Allium sativum L. stem extract on lipid metabolism and antioxidant status in obese mice fed a high-fat diet, Journal of the Science of Food and Agriculture, 93, 2749, 10.1002/jsfa.6094

Kim, 2009, Hypoglycemic and hypolipidemic effects of processed Aloe vera gel in a mouse model of non-insulin-dependent diabetes mellitus, Phytomedicine: International Journal of Phytotherapy and Phytopharmacology, 16, 856, 10.1016/j.phymed.2009.02.014

Kim, 2014, Dietary umbelliferone attenuates alcohol-induced fatty liver via regulation of PPARα and SREBP-1c in rats, Alcohol, 48, 707, 10.1016/j.alcohol.2014.08.008

Kromhout, 1995, Dietary saturated and trans fatty acids and cholesterol and 25-year mortality from coronary heart disease: The seven countries study, Preventive Medicine, 24, 308, 10.1006/pmed.1995.1049

Kubo, 2004, Antibacterial activity of coriander volatile compounds against Salmonella choleraesuis, Journal of Agricultural and Food Chemistry, 52, 3329, 10.1021/jf0354186

Kumari, 2007, Lipid lowering effect of S-methyl cysteine sulfoxide from Allium cepa Linn in high cholesterol diet fed rats, Journal of Ethnopharmacology, 109, 367, 10.1016/j.jep.2006.07.045

Kunkel, 2012, Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease, PloS One, 7, e39332, 10.1371/journal.pone.0039332

Kuo, 2012, Positive effect of curcumin on inflammation and mitochondrial dysfunction in obese mice with liver steatosis, International Journal of Molecular Medicine, 30, 673, 10.3892/ijmm.2012.1049

Kwon, 2015, Luteolin attenuates hepatic steatosis and insulin resistance through the interplay between the liver and adipose tissue in mice with diet-induced obesity, Diabetes, 64, 1658, 10.2337/db14-0631

Labban, 2014, The effects of rosemary (Rosmarinus officinalis) leaves powder on glucose level, lipid profile and lipid perodoxation, International Journal of Clinical Medicine, 05, 297, 10.4236/ijcm.2014.56044

Lai, 2014, Garlic essential oil protects against obesity-triggered nonalcoholic fatty liver disease through modulation of lipid metabolism and oxidative stress, Journal of Agricultural and Food Chemistry, 62, 5897, 10.1021/jf500803c

Lal, 2004, Hypolipidemic effect of Coriandrum sativum L. in triton-induced hyperlipidemic rats, Indian Journal of Experimental Biology, 42, 909

Lee, 2008, Regulation of obesity and lipid disorders by herbal extracts from Morus alba, Melissa officinalis, and Artemisia capillaris in high-fat diet-induced obese mice, Journal of Ethnopharmacology, 115, 263, 10.1016/j.jep.2007.09.029

Lee, 2012, High hydrostatic pressure extract of garlic increases the HDL cholesterol level via up-regulation of apolipoprotein A-I gene expression in rats fed a high-fat diet, Lipids in Health and Disease, 11, 77, 10.1186/1476-511X-11-77

Lee, 2005, Antihyperlipidemic effect of crocin isolated from the fructus of Gardenia jasminoides and its metabolite Crocetin, Biological & Pharmaceutical Bulletin, 28, 2106, 10.1248/bpb.28.2106

Lee, 2010, Leonurus sibiricus herb extract suppresses oxidative stress and ameliorates hypercholesterolemia in C57BL/6 mice and TNF-alpha induced expression of adhesion molecules and lectin-like oxidized LDL receptor-1 in human umbilical vein endothelial cells, Bioscience, Biotechnology and Biochemistry, 74, 279, 10.1271/bbb.90582

Lee, 2013, Topical application of capsaicin reduces visceral adipose fat by affecting adipokine levels in high-fat diet-induced obese mice, Obesity, 21, 115, 10.1002/oby.20246

Lepore, 2015, Oral administration of oleuropein and its semisynthetic peracetylated derivative prevents hepatic steatosis, hyperinsulinemia, and weight gain in mice fed with high fat cafeteria diet, International Journal Endocrinology, 2015, 431453

Li, 2014, Therapeutic role of ursolic acid on ameliorating hepatic steatosis and improving metabolic disorders in high-fat diet-induced non-alcoholic fatty liver disease rats, PloS One, 9, e86724, 10.1371/journal.pone.0086724

Li, 2013, Dietary capsaicin prevents nonalcoholic fatty liver disease through transient receptor potential vanilloid 1-mediated peroxisome proliferator-activated receptor δ activation, Pflügers Archiv: European Journal of Physiology, 465, 1303, 10.1007/s00424-013-1274-4

Lima, 2007, Water and methanolic extracts of Salvia officinalis protect HepG2 cells from t-BHP induced oxidative damage, Chemico-Biological Interactions, 167, 107, 10.1016/j.cbi.2007.01.020

Lim, 2010, The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome, Nature Reviews. Gastroenterology & Hepatology, 7, 251, 10.1038/nrgastro.2010.41

Lin, 2013, Protective effects of Houttuynia cordata aqueous extract in mice consuming a high saturated fat diet, Food & Function, 4, 322, 10.1039/C2FO30228D

Lin, 2015, Potential anti-cancer activities and mechanisms of costunolide and dehydrocostuslactone, International Journal of Molecular Sciences, 16, 10888, 10.3390/ijms160510888

Li, 2003, Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease, Hepatology, 37, 343, 10.1053/jhep.2003.50048

Lustig, 2013, Fructose: it's “alcohol without the buzz”, Advances in Nutrition, 4, 226, 10.3945/an.112.002998

Madak-Erdogan, 2016, Dietary licorice root supplementation reduces diet-induced weight gain, lipid deposition, and hepatic steatosis in ovariectomized mice without stimulating reproductive tissues and mammary gland, Molecular Nutrition & Food Research, 60, 369, 10.1002/mnfr.201500445

Magliano, 2013, Peroxisome proliferator-activated receptors-alpha and gamma are targets to treat offspring from maternal diet-induced obesity in mice, PLoS One, 8, e64258, 10.1371/journal.pone.0064258

Magliano, 2015, Short-term administration of GW501516 improves inflammatory state in white adipose tissue and liver damage in high-fructose-fed mice through modulation of the renin-angiotensin system, Endocrine, 50, 355, 10.1007/s12020-015-0590-1

Ma, 2013, Effects of probiotics on nonalcoholic fatty liver disease: A meta-analysis, World Journal of Gastroenterology, 19, 6911, 10.3748/wjg.v19.i40.6911

Manach, 2004, Polyphenols: Food sources and bioavailability, The American Journal of Clinical Nutrition, 79, 727, 10.1093/ajcn/79.5.727

Mani Badal, 2011, Pharmacological action of mentha piperita on lipid profile in fructose-fed rats, Iranian Journal of Pharmaceutical Research: IJPR, 10, 843

Manosroi, 2006, Anti-proliferative activity of essential oil extracted from Thai medicinal plants on KB and P388 cell lines, Cancer Letters, 235, 114, 10.1016/j.canlet.2005.04.021

Martínez-González, 2015, Benefits of the mediterranean Diet: Insights from the PREDIMED study, Progress in Cardiovascular Diseases, 58, 50, 10.1016/j.pcad.2015.04.003

McCarty, 2005, High mitochondrial redox potential may promote induction and activation of UCP2 in hepatocytes during hepatothermic therapy, Medical Hypotheses, 64, 1216, 10.1016/j.mehy.2004.01.040

McCarty, 2015, Capsaicin may have important potential for promoting vascular and metabolic health, Open Heart, 2, 10.1136/openhrt-2015-000262

Mekonnen, 2016, Vitro antimicrobial activity of essential oil of Thymus schimperi, matricaria chamomilla, Eucalyptus globulus, and rosmarinus officinalis, International Journal of Microbiology, 2016, 9545693, 10.1155/2016/9545693

Menotti, 1999, Food intake patterns and 25-year mortality from coronary heart disease: Cross-cultural correlations in the seven countries study. The seven countries study research group, European Journal of Epidemiology, 15, 507, 10.1023/A:1007529206050

Mirhosseini, 2014, Anethum graveolens and hyperlipidemia: A randomized clinical trial, Journal of Research in Medical Sciences: The Official Journal of Isfahan University of Medical Sciences, 19, 758

Mueller, 2010, Anti-inflammatory activity of extracts from fruits, herbs and spices, Food Chemistry, 122, 987, 10.1016/j.foodchem.2010.03.041

Mueller, 2008, Oregano: A source for peroxisome proliferator-activated receptor gamma antagonists, Journal of Agricultural and Food Chemistry, 56, 11621, 10.1021/jf802298w

Mummadi, 2008, Effect of bariatric surgery on nonalcoholic fatty liver disease: Systematic review and meta-analysis, Clinical Gastroenterology and Hepatology, 6, 1396, 10.1016/j.cgh.2008.08.012

Murat Bilgin, 2011, Protective effects of coumarin and coumarin derivatives against carbon tetrachloride-induced acute hepatotoxicity in rats, Experimental and Toxicologic Pathology, 63, 325, 10.1016/j.etp.2010.02.006

Musso, 2009, Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD), Progress in Lipid Research, 48, 1, 10.1016/j.plipres.2008.08.001

Musso, 2010, A meta-analysis of randomized trials for the treatment of nonalcoholic fatty liver disease, Hepatology, 52, 79, 10.1002/hep.23623

Naowaboot, 2016, Ferulic acid improves lipid and glucose homeostasis in high-fat diet-induced obese mice, Clinical and Experimental Pharmacology & Physiology, 43, 242, 10.1111/1440-1681.12514

Naowaboot, 2015, Umbelliferone improves an impaired glucose and lipid metabolism in high-fat diet/streptozotocin-induced type 2 diabetic rats, Phytotherapy Research, 29, 1388, 10.1002/ptr.5392

Narasimhan, 2015, Ferulic acid regulates hepatic GLUT2 gene expression in high fat and fructose-induced type-2 diabetic adult male rat, European Journal of Pharmacology, 761, 391, 10.1016/j.ejphar.2015.04.043

Nassiri-Asl, 2009, Effects of Urtica dioica extract on lipid profile in hypercholesterolemic rats, Journal of Chinese Integrative Medicine, 7, 428, 10.3736/jcim20090506

Ninomiya, 2004, Carnosic acid, a new class of lipid absorption inhibitor from sage, Bioorganic & Medicinal Chemistry Letters, 14, 1943, 10.1016/j.bmcl.2004.01.091

Okada, 2000, Radical modulating activity and cytotoxic activity of synthesized eugenol-related compounds, Anticancer Research, 20, 2955

Oniga, 2007, Effects of Salvia officinalis L. extract on experimental acute inflammation, Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i, 111, 290

Ozsoy-Sacan, 2006, Effects of parsley (Petroselinum crispum) extract versus glibornuride on the liver of streptozotocin-induced diabetic rats, Journal of Ethnopharmacology, 104, 175, 10.1016/j.jep.2005.08.069

Pallarès, 2013, Grape seed procyanidin extract reduces the endotoxic effects induced by lipopolysaccharide in rats, Free Radical Biology & Medicine, 60, 107, 10.1016/j.freeradbiomed.2013.02.007

Panchal, 2012, Coffee extract attenuates changes in cardiovascular and hepatic structure and function without decreasing obesity in high-carbohydrate, high-fat diet-fed male rats, The Journal of Nutrition, 142, 690, 10.3945/jn.111.153577

Papamiltiadous, 2016, A randomised controlled trial of a mediterranean dietary intervention for adults with non alcoholic fatty liver disease (MEDINA): Study protocol, BMC Gastroenterology, 16, 14, 10.1186/s12876-016-0426-3

Park, 2011, Oleuropein attenuates hepatic steatosis induced by high-fat diet in mice, Journal of Hepatology, 54, 984, 10.1016/j.jhep.2010.08.019

Park, 2015, Reduction of adipose tissue mass by the angiogenesis inhibitor ALS-l1023 from melissa officinalis, PloS One, 10, 10.1371/journal.pone.0141612

Park, 2013, Dietary carnosic acid suppresses hepatic steatosis formation via regulation of hepatic fatty acid metabolism in high-fat diet-fed mice, Nutrition Research and Practice, 7, 294, 10.4162/nrp.2013.7.4.294

Park, 2014, Carnosic acid attenuates obesity-induced glucose intolerance and hepatic fat accumulation by modulating genes of lipid metabolism in C57BL/6J-ob/ob mice, Journal of the Science of Food and Agriculture, 95, 828, 10.1002/jsfa.6973

Peng, 2011, Mulberry water extracts possess an anti-obesity effect and ability to inhibit hepatic lipogenesis and promote lipolysis, Journal of Agricultural and Food Chemistry, 59, 2663, 10.1021/jf1043508

Pereira, 2009, Antioxidant effects of different extracts from melissa officinalis, matricaria recutita and cymbopogon citratus, Neurochemical Research, 34, 973, 10.1007/s11064-008-9861-z

Pessayre, 2004, Mitochondrial injury in steatohepatitis, European Journal of Gastroenterology & Hepatology, 16, 1095, 10.1097/00042737-200411000-00003

Peterson, 2006, Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1, Food and Chemical Toxicology, 44, 1474, 10.1016/j.fct.2006.04.010

Portillo, 2001, Differential effects of diets that provide different lipid sources on hepatic lipogenic activities in rats under ad libitum or restricted feeding, Nutrition, 17, 467, 10.1016/S0899-9007(01)00513-5

Posadzki, 2013, Adverse effects of herbal medicines: An overview of systematic reviews, Clinical Medicine, 13, 7, 10.7861/clinmedicine.13-1-7

Priore, 2015, Modulation of hepatic lipid metabolism by olive oil and its phenols in nonalcoholic fatty liver disease, IUBMB Life, 67, 9, 10.1002/iub.1340

Priore, 2014, Extra virgin olive oil phenols down-regulate lipid synthesis in primary-cultured rat-hepatocytes, The Journal of Nutritional Biochemistry, 25, 683, 10.1016/j.jnutbio.2014.01.009

Prior, 2010, Purified blueberry anthocyanins and blueberry juice alter development of obesity in mice fed an obesogenic high-fat diet, Journal of Agricultural and Food Chemistry, 58, 3970, 10.1021/jf902852d

Promrat, 2010, Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis, Hepatology, 51, 121, 10.1002/hep.23276

Ramesh, 2005, Antihyperlipidemic and antidiabetic effects of umbelliferone in streptozotocin diabetic rats, The Yale Journal of Biology and Medicine, 78, 189

Raskin, 2000, Rosiglitazone short-term monotherapy lowers fasting and post-prandial glucose in patients with type II diabetes, Diabetologia, 43, 278, 10.1007/s001250050045

Rautiainen, 2016, Dietary supplements and disease prevention - a global overview, Nature Reviews Endocrinology, 12, 407, 10.1038/nrendo.2016.54

Rau, 2006, Carnosic acid and carnosol, phenolic diterpene compounds of the labiate herbs rosemary and sage, are activators of the human peroxisome proliferator-activated receptor gamma, Planta Medica, 72, 881, 10.1055/s-2006-946680

Rebey, 2012, Polyphenol composition and antioxidant activity of cumin (Cuminum cyminum L.) seed extract under drought, Journal of Food Science, 77, C734, 10.1111/j.1750-3841.2012.02731.x

Rood, 2014, Effects of Artemisia species on de novo lipogenesis in vivo, Nutrition, 30, S17, 10.1016/j.nut.2014.03.029

Roy, 2013, Treatment with ferulic acid to rats with streptozotocin-induced diabetes: Effects on oxidative stress, pro-inflammatory cytokines, and apoptosis in the pancreatic β cell, Endocrine, 44, 369, 10.1007/s12020-012-9868-8

Rufino, 2015, Evaluation of the anti-inflammatory, anti-catabolic and pro-anabolic effects of E-caryophyllene, myrcene and limonene in a cell model of osteoarthritis, European Journal of Pharmacology, 750, 141, 10.1016/j.ejphar.2015.01.018

Salas-Salvadó, 2016, Protective effects of the mediterranean diet on type 2 diabetes and metabolic syndrome, The Journal of Nutrition, 146, 920S, 10.3945/jn.115.218487

Salvado, 2012, Targeting PPARbeta/delta for the treatment of type 2 diabetes mellitus, Expert Opinion on Therapeutic Targets, 16, 209, 10.1517/14728222.2012.658370

Sánchez-Villegas, 2013, Mediterranean dietary pattern and depression: The PREDIMED randomized trial, BMC Medicine, 11, 208, 10.1186/1741-7015-11-208

Sá, 2009, Sage tea drinking improves lipid profile and antioxidant defences in humans, International Journal of Molecular Sciences, 10, 3937, 10.3390/ijms10093937

Sartorius, 2014, Cinnamon extract improves insulin sensitivity in the brain and lowers liver fat in mouse models of obesity, PloS One, 9, e92358, 10.1371/journal.pone.0092358

Sasaki, 2007, Cyanidin 3-glucoside ameliorates hyperglycemia and insulin sensitivity due to downregulation of retinol binding protein 4 expression in diabetic mice, Biochemical Pharmacology, 74, 1619, 10.1016/j.bcp.2007.08.008

Sato, 2007, Dietary palatinose and oleic acid ameliorate disorders of glucose and lipid metabolism in Zucker fatty rats, The Journal of Nutrition, 137, 1908, 10.1093/jn/137.8.1908

Satoh, 2008, Carnosic acid protects neuronal HT22 Cells through activation of the antioxidant-responsive element in free carboxylic acid- and catechol hydroxyl moieties-dependent manners, Neuroscience Letters, 434, 260, 10.1016/j.neulet.2008.01.079

Schoonjans, 1995, Induction of the acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter, The Journal of Biological Chemistry, 270, 19269, 10.1074/jbc.270.33.19269

Schuhmacher, 2003, Virucidal effect of peppermint oil on the enveloped viruses herpes simplex virus type 1 and type 2 in vitro, Phytomedicine: International Journal of Phytotherapy and Phytopharmacology, 10, 504, 10.1078/094471103322331467

Seidell, 2015, The global burden of obesity and the challenges of prevention, Annals of Nutrition & Metabolism, 66, 7, 10.1159/000375143

Setorki, 2013, Suppressive impact of anethum graveolens consumption on biochemical risk factors of atherosclerosis in hypercholesterolemic rabbits, International Journal of Preventive Medicine, 4, 889

Shan, 2015, Activation of the SIRT1/p66shc antiapoptosis pathway via carnosic acid-induced inhibition of miR-34a protects rats against nonalcoholic fatty liver disease, Cell Death & Disease, 6, e1833, 10.1038/cddis.2015.196

Sharma, 2013, Mechanisms and clinical uses of capsaicin, European Journal of Pharmacology, 720, 55, 10.1016/j.ejphar.2013.10.053

Shavakhi, 2015, Effects of cumin on nonalcoholic steatohepatitis: A double blind, randomised, controlled trial, Advanced Biomedical Research, 4, 212

Sheng, 2006, Mechanism of hypolipidemic effect of crocin in rats: Crocin inhibits pancreatic lipase, European Journal of Pharmacology, 543, 116, 10.1016/j.ejphar.2006.05.038

Shen, 2010, LC-MS method for the simultaneous quantitation of the anti-inflammatory constituents in oregano (Origanum species), Journal of Agricultural and Food Chemistry, 58, 7119, 10.1021/jf100636h

Shen, 2014, Olive leaf extract attenuates obesity in high-fat diet-fed mice by modulating the expression of molecules involved in adipogenesis and thermogenesis, Evidence-Based Complementary and Alternative Medicine: eCAM, 2014, 971890, 10.1155/2014/971890

Shin, 2009, Anti-inflammatory activity of motherwort (leonurus sibiricus L.), Immunopharmacology and Immunotoxicology, 31, 209, 10.1080/08923970802135443

Sim, 2014, Long-term supplementation of umbelliferone and 4-methylumbelliferone alleviates high-fat diet induced hypertriglyceridemia and hyperglycemia in mice, Chemico-Biological Interactions, 216, 9, 10.1016/j.cbi.2014.03.003

Sitarek, 2016, The effect of leonurus sibiricus plant extracts on stimulating repair and protective activity against oxidative DNA damage in CHO cells and content of phenolic compounds, Oxidative Medicine and Cellular Longevity, 2016, 5738193, 10.1155/2016/5738193

Slimestad, 2007, Onions: A source of unique dietary flavonoids, Journal of Agricultural and Food Chemistry, 55, 10067, 10.1021/jf0712503

Sofi, 2010, Accruing evidence on benefits of adherence to the mediterranean diet on health: An updated systematic review and meta-analysis, The American Journal of Clinical Nutrition, 92, 1189, 10.3945/ajcn.2010.29673

Sofi, 2014, Mediterranean diet and non-alcoholic fatty liver disease: New therapeutic option around the corner?, World Journal of Gastroenterology, 20, 7339, 10.3748/wjg.v20.i23.7339

Softic, 2016, Role of dietary fructose and hepatic de novo lipogenesis in fatty liver disease, Digestive Diseases and Sciences, 61, 1282, 10.1007/s10620-016-4054-0

Soriguer, 2006, Pro12Ala polymorphism of the PPARG2 gene is associated with type 2 diabetes mellitus and peripheral insulin sensitivity in a population with a high intake of oleic acid, The Journal of Nutrition, 136, 2325, 10.1093/jn/136.9.2325

Souza-Mello, 2015, Peroxisome proliferator-activated receptors as targets to treat non-alcoholic fatty liver disease, World Journal of Hepatology, 7, 1012, 10.4254/wjh.v7.i8.1012

Souza-Mello, 2010, Comparative effects of telmisartan, sitagliptin and metformin alone or in combination on obesity, insulin resistance, and liver and pancreas remodelling in C57BL/6 mice fed on a very high-fat diet, Clinical Science, 119, 239, 10.1042/CS20100061

Sri Balasubashini, 2003, Protective effects of ferulic acid on hyperlipidemic diabetic rats, Acta Diabetologica, 40, 118, 10.1007/s00592-003-0099-6

Srivastava, 2010, Crocus sativus L.: A comprehensive review, Pharmacognosy Reviews, 4, 200, 10.4103/0973-7847.70919

St George, 2009, Independent effects of physical activity in patients with nonalcoholic fatty liver disease, Hepatology, 50, 68, 10.1002/hep.22940

Stanhope, 2016, Sugar consumption, metabolic disease and obesity: The state of the controversy, Critical Reviews in Clinical Laboratory Sciences, 53, 52, 10.3109/10408363.2015.1084990

Sundaresan, 2014, Effect of ursolic acid and Rosiglitazone combination on hepatic lipid accumulation in high fat diet-fed C57BL/6J mice, European Journal of Pharmacology, 741, 297, 10.1016/j.ejphar.2014.07.032

Sun, 2013, TRPV1-mediated UCP2 upregulation ameliorates hyperglycemia-induced endothelial dysfunction, Cardiovascular Diabetology, 12, 69, 10.1186/1475-2840-12-69

Takahashi, 2013, Dill seed extract improves abnormalities in lipid metabolism through peroxisome proliferator-activated receptor-α (PPAR-α) activation in diabetic obese mice, Molecular Nutrition & Food Research, 57, 1295, 10.1002/mnfr.201200767

Thoma, 2012, Lifestyle interventions for the treatment of non-alcoholic fatty liver disease in adults: A systematic review, Journal of Hepatology, 56, 255, 10.1016/j.jhep.2011.06.010

Toledo, 2015, Mediterranean diet and invasive breast cancer risk among women at high cardiovascular risk in the PREDIMED trial: A randomized clinical trial, JAMA Internal Medicine, 175, 1752, 10.1001/jamainternmed.2015.4838

Tu, 2013, Rosemary (Rosmarinus officinalis L.) extract regulates glucose and lipid metabolism by activating AMPK and PPAR pathways in HepG2 cells, Journal of Agricultural and Food Chemistry, 61, 2803, 10.1021/jf400298c

Udani, 2011, Effects of açai (euterpe oleracea mart.) berry preparation on metabolic parameters in a healthy overweight population: A pilot study, Nutrition Journal, 10, 45, 10.1186/1475-2891-10-45

Umar, 2012, The hypolipidemic and antioxidant actions of aqueous extracts of Ocimum basilicum and Ocimum suave in high fat fed Rats, Journal of Medicinal Plants Research, 6, 3501

Vadivel, 2012, Health benefits of nut consumption with special reference to body weight control, Nutrition, 28, 1089, 10.1016/j.nut.2012.01.004

Valls-Pedret, 2015, Mediterranean diet and age-related cognitive decline: A randomized clinical trial, JAMA Internal Medicine, 175, 1094, 10.1001/jamainternmed.2015.1668

Velayudham, 2009, VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice, Hepatology, 49, 989, 10.1002/hep.22711

Vernia, 1995, Short-chain fatty acid topical treatment in distal ulcerative colitis, Alimentary Pharmacology & Therapeutics, 9, 309, 10.1111/j.1365-2036.1995.tb00386.x

Victor Antony Santiago, 2012, Dietary d-limonene alleviates insulin resistance and oxidative stress-induced liver injury in high-fat diet and L-NAME-treated rats, European Journal of Nutrition, 51, 57, 10.1007/s00394-011-0182-7

Vilar-Gomez, 2015, Weight loss through lifestyle modification significantly reduces features of nonalcoholic steatohepatitis, Gastroenterology, 149, 367, 10.1053/j.gastro.2015.04.005

Visioli, 2002, Biological properties of olive oil phytochemicals, Critical Reviews in Food Science and Nutrition, 42, 209, 10.1080/10408690290825529

Vissers, 2002, Olive oil phenols are absorbed in humans, The Journal of Nutrition, 132, 409, 10.1093/jn/132.3.409

Vlase, 2014, Evaluation of antioxidant and antimicrobial activities and phenolic profile for Hyssopus officinalis, Ocimum basilicum and Teucrium chamaedrys, Molecules, 19, 5490, 10.3390/molecules19055490

Van Wagner, 2011, Pentoxifylline for the treatment of non-alcoholic steatohepatitis: A randomized controlled trial, Annals of Hepatology, 10, 277, 10.1016/S1665-2681(19)31539-X

Wang, 2012, Carnosic acid (CA) prevents lipid accumulation in hepatocytes through the EGFR/MAPK pathway, Journal of Gastroenterology, 47, 805, 10.1007/s00535-012-0546-7

Weidner, 2013, Antidiabetic effects of chamomile flowers extract in obese mice through transcriptional stimulation of nutrient sensors of the peroxisome proliferator-activated receptor (PPAR) family, PloS One, 8, e80335, 10.1371/journal.pone.0080335

Weisberg, 2008, Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity, Endocrinology, 149, 3549, 10.1210/en.2008-0262

Xiao, 2013, Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model, European Journal of Nutrition, 52, 179, 10.1007/s00394-012-0301-0

Xiao, 2013, Garlic-derived S-Allylmercaptocysteine ameliorates nonalcoholic fatty liver disease in a rat model through inhibition of apoptosis and enhancing autophagy, Evidence-Based Complementary and Alternative Medicine: eCAM, 2013, 642920, 10.1155/2013/642920

Yilmaz, 2012, Review article: Is non-alcoholic fatty liver disease a spectrum, or are steatosis and non-alcoholic steatohepatitis distinct conditions?, Alimentary Pharmacology & Therapeutics, 36, 815, 10.1111/apt.12046

Yoon, 2011, The anti-angiogenic herbal composition Ob-X from Morus alba, Melissa officinalis, and Artemisia capillaris regulates obesity in genetically obese ob/ob mice, Pharmaceutical Biology, 49, 614, 10.3109/13880209.2010.539617

Zamora-Ros, 2010, Estimation of dietary sources and flavonoid intake in a Spanish adult population (EPIC-Spain), Journal of the American Dietetic Association, 110, 390, 10.1016/j.jada.2009.11.024

Zeggwagh, 2007, Anti-hyperglycaemic and hypolipidemic effects of Ocimum basilicum aqueous extract in diabetic rats, American Journal of Pharmacology and Toxicology, 2, 123, 10.3844/ajptsp.2007.123.129

Zhang, 2012, Hepatic suppression of Foxo1 and Foxo3 causes hypoglycemia and hyperlipidemia in mice, Endocrinology, 153, 631, 10.1210/en.2011-1527

Zhao, 2015, Carnosic acid as a major bioactive component in rosemary extract ameliorates high-fat-diet-induced obesity and metabolic syndrome in mice, Journal of Agricultural and Food Chemistry, 63, 4843, 10.1021/acs.jafc.5b01246

Zheng, 2001, Antioxidant activity and phenolic compounds in selected herbs, Journal of Agricultural and Food Chemistry, 49, 5165, 10.1021/jf010697n