Singular effects of PPAR agonists on nonalcoholic fatty liver disease of diet-induced obese mice

Life Sciences - Tập 127 - Trang 73-81 - 2015
Sandra Barbosa-da-Silva1, Vanessa Souza-Mello1, D'Angelo Carlo Magliano1, Thatiany de Souza Marinho1, Marcia Barbosa Aguila1, Carlos Alberto Mandarim-de-Lacerda1
1Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Brazil

Tài liệu tham khảo

Aguila, 2010, Hepatic insulin resistance and nonalcoholic fatty liver disease, 1 Chen, 2014, PPARs and metabolic syndrome, PPAR Res., 832606 Tenenbaum, 2005, Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: the bezafibrate lessons, Cardiovasc. Diabetol., 4, 14, 10.1186/1475-2840-4-14 Liu, 2011, Role of peroxisome proliferator-activated receptor {delta}/{beta} in hepatic metabolic regulation, J. Biol. Chem., 286, 1237, 10.1074/jbc.M110.138115 Fraulob, 2012, Beneficial effects of rosuvastatin on insulin resistance, adiposity, inflammatory markers and non-alcoholic fatty liver disease in mice fed on a high-fat diet, Clin. Sci. (Lond.), 123, 259, 10.1042/CS20110373 Ferramosca, 2014, Modulation of hepatic steatosis by dietary fatty acids, World J. Gastroenterol., 20, 1746, 10.3748/wjg.v20.i7.1746 Reeves, 1993, AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet, J. Nutr., 123, 1939, 10.1093/jn/123.11.1939 Souza-Mello, 2007, Hepatic structural alteration in adult programmed offspring (severe maternal protein restriction) is aggravated by post-weaning high-fat diet, Br. J. Nutr., 98, 1159, 10.1017/S0007114507771878 Yin, 1982, Use of tibial length to quantify cardiac hypertrophy: application in the aging rat, Am. J. Physiol., 243, H941 Catta-Preta, 2011, A critical analysis of three quantitative methods of assessment of hepatic steatosis in liver biopsies, Virchows Arch., 459, 477, 10.1007/s00428-011-1147-1 Aguila, 2003, Dietary effect of different high-fat diet on rat liver stereology, Liver Int., 23, 363, 10.1034/j.1478-3231.2003.00858.x Magliano, 2013, Peroxisome proliferator-activated receptors-alpha and gamma are targets to treat offspring from maternal diet-induced obesity in mice, PLoS One, 8, e64258, 10.1371/journal.pone.0064258 Nakamura, 2013, Lessons from mouse models of high-fat diet-induced NAFLD, Int. J. Mol. Sci., 14, 21240, 10.3390/ijms141121240 Fraulob, 2010, A mouse model of metabolic syndrome: insulin resistance, fatty liver and non-alcoholic fatty pancreas disease (NAFPD) in C57BL/6 mice fed a high fat diet, J. Clin. Biochem. Nutr., 46, 212, 10.3164/jcbn.09-83 Maury, 2010, Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome, Mol. Cell. Endocrinol., 314, 1, 10.1016/j.mce.2009.07.031 Briggs, 2013, Calorie-restricted weight loss reverses high-fat diet-induced ghrelin resistance, which contributes to rebound weight gain in a ghrelin-dependent manner, Endocrinology, 154, 709, 10.1210/en.2012-1421 Gustafson, 2007, Inflamed adipose tissue: a culprit underlying the metabolic syndrome and atherosclerosis, Arterioscler. Thromb. Vasc. Biol., 27, 2276, 10.1161/ATVBAHA.107.147835 Van Wagner, 2011, The role of insulin-sensitizing agents in the treatment of nonalcoholic steatohepatitis, Ther. Adv. Gastroenterol., 4, 249, 10.1177/1756283X11403809 Tolman, 2011, The safety of thiazolidinediones, Expert Opin. Drug Saf., 10, 419, 10.1517/14740338.2011.534982 Souza-Mello, 2010, Comparative effects of telmisartan, sitagliptin and metformin alone or in combination on obesity, insulin resistance, and liver and pancreas remodelling in C57BL/6 mice fed on a very high-fat diet, Clin. Sci. (Lond.), 119, 239, 10.1042/CS20100061 Festi, 2004, Hepatic steatosis in obese patients: clinical aspects and prognostic significance, Obes. Rev., 5, 27, 10.1111/j.1467-789X.2004.00126.x Cong, 2008, The establishment of a novel non-alcoholic steatohepatitis model accompanied with obesity and insulin resistance in mice, Life Sci., 82, 983, 10.1016/j.lfs.2008.01.022 Clemenz, 2008, Liver-specific peroxisome proliferator-activated receptor alpha target gene regulation by the angiotensin type 1 receptor blocker telmisartan, Diabetes, 57, 1405, 10.2337/db07-0839 Campbell, 2004, A novel function for fatty acid translocase (FAT)/CD36: involvement in long chain fatty acid transfer into the mitochondria, J. Biol. Chem., 279, 36235, 10.1074/jbc.M400566200 Serviddio, 2011, Oxidation of hepatic carnitine palmitoyl transferase-I (CPT-I) impairs fatty acid beta-oxidation in rats fed a methionine–choline deficient diet, PLoS One, 6, e24084, 10.1371/journal.pone.0024084 Lee, 2002, Fenofibrate lowers abdominal and skeletal adiposity and improves insulin sensitivity in OLETF rats, Biochem. Biophys. Res. Commun., 296, 293, 10.1016/S0006-291X(02)00822-7 Hammer, 1978, The role of lipid components of the diet in the regulation of the fatty acid composition of the rat liver endoplasmic reticulum and lipid peroxidation, Biochem. J., 174, 585, 10.1042/bj1740585 Zhou, 2008, Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis, Gastroenterology, 134, 556, 10.1053/j.gastro.2007.11.037 Frederico, 2011, Short-term inhibition of SREBP-1c expression reverses diet-induced non-alcoholic fatty liver disease in mice, Scand. J. Gastroenterol., 46, 1381, 10.3109/00365521.2011.613945 Cao, 2012, The C-681G polymorphism of the PPAR-gamma gene is associated with susceptibility to non-alcoholic fatty liver disease, Tohoku J. Exp. Med., 227, 253, 10.1620/tjem.227.253 Brunt, 1999, Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions, Am. J. Gastroenterol., 94, 2467, 10.1111/j.1572-0241.1999.01377.x Friedman, 2008, Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver, Physiol. Rev., 88, 125, 10.1152/physrev.00013.2007 Lee, 2011, Mechanisms of hepatic fibrogenesis, Best Pract. Res. Clin. Gastroenterol., 25, 195, 10.1016/j.bpg.2011.02.005 Hazra, 2004, Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells, J. Biol. Chem., 279, 11392, 10.1074/jbc.M310284200 Marra, 2000, Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells, Gastroenterology, 119, 466, 10.1053/gast.2000.9365 Galli, 2002, Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro, Gastroenterology, 122, 1924, 10.1053/gast.2002.33666 Kostadinova, 2012, GW501516-activated PPARbeta/delta promotes liver fibrosis via p38–JNK MAPK-induced hepatic stellate cell proliferation, Cell Biosci., 2, 34, 10.1186/2045-3701-2-34 Peters, 2011, Dissecting the role of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in colon, breast, and lung carcinogenesis, Cancer Metastasis Rev., 30, 619, 10.1007/s10555-011-9320-1