Lipolytic effect of a polyphenolic citrus dry extract of red orange, grapefruit, orange (SINETROL) in human body fat adipocytes. Mechanism of action by inhibition of cAMP-phosphodiesterase (PDE)

Ballard, 2006, Naringin does not alter caffeine pharmacokinetics, energy expenditure, or cardiovascular haemodynamics in humans following caffeine consumption, Clin. Exp. Pharmacol. Physiol., 33, 310, 10.1111/j.1440-1681.2006.04367.x

Balkau, 2007, International day for the evaluation of abdominal obesity (IDEA) a study of waist circumference, cardiovascular disease, and diabetes mellitus in 168,000 primary care patients in 63 countries, Circulation, 116, 1942, 10.1161/CIRCULATIONAHA.106.676379

Beavo, 1971, Effects of phosphodiesterase inhibitors on cyclic AMP levels and on lipolysis, Ann. N Y Acad. Sci., 185, 129, 10.1111/j.1749-6632.1971.tb45243.x

Chen, 2004, Green tea and tea polyphenols in cancer prevention, Front Biosci., 9, 2618, 10.2741/1421

Dallas, 1994, Effect of SO2 on the extraction of individual anthocyanins and colored matter of tree Portuguese grape varieties during winemaking, Vitis, 33, 41

Dallas, 1994, Effects of pH, sulphur dioxide, alcohol content, temperature and storage time on colour composition of a young Portuguese red wine table, J. Sci. Food Agric., 65, 477, 10.1002/jsfa.2740650416

Dallas, 1995, Degradation of oligomeric procyanidins and anthocyanins in Tinta roriz red wine during maturation, Vitis, 34, 51

Dallas, 1996, Products formed in model wine solutions involving anthocyanins, procyanidin B2 and acetaldehyde, J. Agric. Food Chem., 44, 2402, 10.1021/jf940433j

Dallas, 1996, Interactions of oligomeric procyanidins in model wine solutions containing malvidin-3 glucoside and acetaldehyde, J. Sci. Food Agric., 70, 493, 10.1002/(SICI)1097-0010(199604)70:4<493::AID-JSFA528>3.0.CO;2-7

Frankel, 1993, Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine, Lancet, 341, 454, 10.1016/0140-6736(93)90206-V

Fujioka, 2006, The effects of grapefruit on weight and insulin resistance: relationship to the metabolic syndrome, J. Med. Food, 9, 49, 10.1089/jmf.2006.9.49

Girotti, 2005, Lipolytic activity of cirsimarin extracted from Microtea debilis, Planta Med., 71, 1170, 10.1055/s-2005-873146

Jiang, 1998, Isolation of lipolytic substances caffeine and 1,7-dimethylxanthine from the stem and rhizome of sinomenium actum, Planta Med., 64, 375, 10.1055/s-2006-957456

Kuppusamy, 1992, Effects of flavonoids on cyclic AMP phosphodiesterase and lipid mobilization in rat adipocytes, Biochem. Pharmacol., 44, 1307, 10.1016/0006-2952(92)90531-M

Laughton, 1991, Inhibition of mammalian 5-lipoxygenase and cyclo-oxygenase by flavonoids and phenolic dietary additives. Relationship to antioxidant activity and to iron ion-reducing ability, Biochem. Pharmacol., 42, 1673, 10.1016/0006-2952(91)90501-U

Mochizuki, 2004, Pycnogenol stimulates lipolysis in 3t3-L1 cells via stimulation of beta-receptor mediated activity, Phytother. Res., 18, 1029, 10.1002/ptr.1612

Mochizuki, 2004, Effects of green tea catechin-induced lipolysis on cytosol glycerol content in differentiated 3T3-L1 cells, Phytother. Res., 18, 945, 10.1002/ptr.1580

Orgogozo, 1997, Wine consumption and dementia in the elderly: a prospective community study in the Bordeaux area, Rev. Neurol., 153, 185

Renold, A.E., Cahill, G.F., 1965. Handbook of Physiology. Section 5. Adipose Tissue. American Physiological Society, Washington, DC.

Robidoux, 2006, Maximal beta3-adrenergic regulation of lipolysis involves Src and epidermal growth factor receptor-dependent ERK1/2 activation, J. Biol. Chem., 281, 37794, 10.1074/jbc.M605572200

Rodbell, 1964, Metabolism of isolated fat cells. I effect of hormones on glucose metabolism and lipolysis, J. Biol. Chem., 239, 375, 10.1016/S0021-9258(18)51687-2

Shixian, 2006, Green tea extract thermogenesis-induced weight loss by epigallocatechin gallate inhibition of catechol-O-methyltransferase, J. Med. Food, 9, 451, 10.1089/jmf.2006.9.451

Spector, 1975, Fatty acid binding to plasma albumin, J. Lipid Res., 16, 165, 10.1016/S0022-2275(20)36723-7

Steinberg, 1977, Hormone-sensitive lipase of adipose tissue, Fed. Pmc., 36, 1986

Tsuda, 2005, Gene expression profile of isolated rat adipocytes treated with anthocyanins, Biochim. Biophys. Acta, 1733, 137, 10.1016/j.bbalip.2004.12.014

Yoshikawa, 2002, Salacia reticulata and its polyphenolic constituents with lipase inhibitory and lipolytic activities have mild antiobesity effects in rats, J. Nutr., 132, 1819, 10.1093/jn/132.7.1819