Preventive and ameliorating effects of citrus d-limonene on dyslipidemia and hyperglycemia in mice with high-fat diet-induced obesity

European Journal of Pharmacology - Tập 715 Số 1-3 - Trang 46-55 - 2013
Jing Li1,2, Yu Zhang3, Shengjie Fan3, Ming Gu3, Yu Guan3, Xiong Lu4, Cheng Huang3, Zhiqin Zhou1,2
1College of Horticulture and Landscape Architecture, Southwest University, Chongqing 400716, China
2Key Laboratory of Horticulture Science for Southern Mountainous Regions, Ministry of Education, Chongqing 400715, China
3Drug Discovery Laboratory, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
4Scientific Experimental Center, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China

Tóm tắt

Từ khóa


Tài liệu tham khảo

Ahima, 2011, Digging deeper into obesity, J. Clin. Invest., 121, 2076, 10.1172/JCI58719

Bakkali, 2008, Biological effects of essential oils—a review, Food Chem. Toxicol., 46, 446, 10.1016/j.fct.2007.09.106

Barter, 2008, Is there a role for fibrates in the management of dyslipidemia in the metabolic syndrome?, Arteriosclerosis, Thrombosis, Vascular Biol., 28, 39, 10.1161/ATVBAHA.107.148817

Berger, 2005, PPARs: therapeutic targets for metabolic disease, Trends Pharmacol. Sci., 26, 244, 10.1016/j.tips.2005.03.003

Canbakan, 2008, Leptin in nonalcoholic fatty liver disease, Ann. Hepatol., 7, 249, 10.1016/S1665-2681(19)31856-3

Chun, 2010, Genetic link between obesity and MMP14-dependent adipogenic collagen turnover, Diabetes, 59, 2484, 10.2337/db10-0073

Chung, 2010, Anti-diabetic effects of lemon balm ( Melissa officinalis) essential oil on glucose- and lipid-regulating enzymes in type 2 diabetic mice, Br. J. Nutr., 104, 180, 10.1017/S0007114510001765

Clegg, 1980, Inhibition of hepatic cholesterol synthesis and S-3-hydroxy-3-methylglutaryl-CoA reductase by mono and bicyclic monoterpenes administered in vivo, Biochem. Pharmacol., 29, 2125, 10.1016/0006-2952(80)90183-5

Clegg, 1982, The mechanism of cyclic monoterpene inhibition of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase in vivo in the rat, J. Biol. Chem., 257, 2294, 10.1016/S0021-9258(18)34920-2

Eberlé, 2004, SREBF-1 gene polymorphisms are associated with obesity and type 2 diabetes in French obese and diabetic cohorts, Diabetes, 53, 2153, 10.2337/diabetes.53.8.2153

Fukumoto, 2008, Effect of flavour components in lemon essential oil on physical or psychological stress, Stress Health, 24, 3, 10.1002/smi.1158

Gabbi, 2009, Minireview: Liver X Receptor β: emerging roles in physiology and diseases, Mol. Endocrinol., 23, 129, 10.1210/me.2008-0398

Genest, 2003, Recommendations for the management of dyslipidemia and the prevention of cardiovascular disease: summary of the 2003 update, Can. Med. Assoc. J., 169, 921

Goldberg, 2005, A comparison of lipid and glycemic effects of pioglitazone and rosiglitazone in patients with type 2 diabetes and dyslipidemia, Diabetes Care, 28, 1547, 10.2337/diacare.28.7.1547

Goldwasser, 2010, Transcriptional regulation of human and rat hepatic lipid metabolism by the grapefruit flavonoid naringenin: role of PPARα, PPARγ and LXRα, PLoS ONE, 5, e12399, 10.1371/journal.pone.0012399

Gong, 2009, The Role of Tanshinone IIA in the treatment of obesity through peroxisome proliferator-activated receptor γ antagonism, Endocrinology, 150, 104, 10.1210/en.2008-0322

Jay, 2007, Peroxisome proliferator-activated receptor (PPAR) in metabolic syndrome and type 2 diabetes mellitus, Curr. Diabetes Rev., 3, 33, 10.2174/157339907779802067

Kawakami, 2004, Effects of phytoncides on blood pressure under restraint stress in SHRSP, Clin. Exp. Pharmacol. Physiol., 31, S27, 10.1111/j.1440-1681.2004.04102.x

Keen, 2004, Gene expression profiling of potential PPARγ target genes in mouse aorta, Physiol. Genomics, 18, 33, 10.1152/physiolgenomics.00027.2004

Kim, 2012, Citrus aurantium flavonoids inhibit adipogenesis through the Akt signaling pathway in 3T3-L1 cells, BMC Complementary Alternative Med., 12, 31, 10.1186/1472-6882-12-31

Kim, 2012, Potent PPARα activator derived from tomato juice, 13-oxo-9,11-octadecadienoic acid, decreases plasma and hepatic triglyceride in obese diabetic mice, PLoS ONE, 7, e31317, 10.1371/journal.pone.0031317

Kumar Sharma, 2011, Up-regulation of PPARγ, heat shock protein-27 and -72 by naringin attenuates insulin resistance, β-cell dysfunction, hepatic steatosis and kidney damage in a rat model of type 2 diabetes, Br. J. Nutr., 106, 1713, 10.1017/S000711451100225X

Miller, 2011, d-Limonene: a bioactive food component from citrus and evidence for a potential role in breast cancer prevention and treatment, Oncol. Rev., 5, 31, 10.1007/s12156-010-0066-8

Mulvihill, 2009, Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistance, Diabetes, 58, 2198, 10.2337/db09-0634

Pandima Devi, 2004, Protective effect of Premna tomentosa (L. Verbenaceae) extract on membrane-bound phosphatases and inorganic cations transport in acetaminophen-induced hepatotoxicity rats, J. Ethnopharmacol., 93, 371, 10.1016/j.jep.2004.04.010

Pruessner, 2003, Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change, Psychoneuroendocrinology, 28, 916, 10.1016/S0306-4530(02)00108-7

Rakhshandehroo, 2010, Peroxisome proliferator-activated receptor alpha target genes, PPAR Research 2010, 1, 10.1155/2010/612089

Repa, 2000, The role of orphan nuclear receptors in the regulation of cholesterol homeostasis, Annu. Rev. Cell Dev. Biol., 16, 459, 10.1146/annurev.cellbio.16.1.459

Seidell, 1995, The impact of obesity on health status: some implications for health care costs, Int. J. Obesity Relat. Metab. Disord.: J. Int. Assoc. Study Obesity, 19, S13

Shibata, 1991, Immunological and behavioral effects of fragrance in mice, Int. J. Neurosci., 57, 151, 10.3109/00207459109150355

Shu, G., 2010. Use of volatile oil from plants in preparing medicaments for preventing and treating diabetes. Google Patents.

Staels, 2007, PPAR agonists and the metabolic syndrome, Therapie, 62, 319, 10.2515/therapie:2007051

Sun, 2007, d-Limonene: safety and clinical applications, Alternative Med. Rev., 12, 259

Tiraby, 2003, Conversion from white to brown adipocytes: a strategy for the control of fat mass?, Trends Endocrinol. Metab., 14, 439, 10.1016/j.tem.2003.10.001

Tontonoz, 2003, Liver X Receptor signaling pathways in cardiovascular disease, Mol. Endocrinol., 17, 985, 10.1210/me.2003-0061

Ulven, 2004, Tissue-specific autoregulation of the LXRα gene facilitates induction of apoE in mouse adipose tissue, J. Lipid Res., 45, 2052, 10.1194/jlr.M400119-JLR200

Santiago, 2012, Dietary d-limonene alleviates insulin resistance and oxidative stress-induced liver injury in high-fat diet and L-NAME-treated rats, Eur. J. Nutr., 51, 57, 10.1007/s00394-011-0182-7

Vigushin, 1998, Phase I and pharmacokinetic study of d-limonene in patients with advanced cancer, Cancer Chemother. Pharmacol., 42, 111, 10.1007/s002800050793

Wang, 2011, Health and economic burden of the projected obesity trends in the USA and the UK, The Lancet, 378, 815, 10.1016/S0140-6736(11)60814-3

Yang, 2010, Chemical composition and antioxidant activity of essential oil of pine cones of Pinus armandii from the southwest region of China, J. Med. Plants Res., 4, 1668

Yoon, 2009, The role of PPARα in lipid metabolism and obesity: focusing on the effects of estrogen on PPARα actions, Pharmacol. Res., 60, 151, 10.1016/j.phrs.2009.02.004

Yun, 2010, Possible anti-obesity therapeutics from nature—a review, Phytochemistry, 71, 1625, 10.1016/j.phytochem.2010.07.011