Effects of parsley (Petroselinum crispum) on the liver of diabetic rats: a morphological and biochemical study

Phytotherapy Research - Tập 18 Số 12 - Trang 996-999 - 2004
Sema Bolkent1, Refiye Yanardağ2, Özlem Saçan2, Ömür Karabulut Bulan1
1Department of Biology, Faculty of Science, Istanbul University, 34459 Vezneciler, Istanbul, Turkey
2Department of Chemistry, Faculty of Engineering, Istanbul University, 34850 Avcılar-Istanbul, Turkey

Tóm tắt

AbstractParsley is used by diabetics in Turkey to reduce blood glucose. The present study aims to investigate both the morphological and biochemical effects of parsley on liver tissue. Rat hepatocytes were examined by light and electron microscopy. Degenerative changes were observed in the hepatocytes of diabetic rats. These degenerative changes were significantly reduced or absent in the hepatocytes of diabetic rats treated with parsley. Blood glucose levels, alanine transaminase and alkaline phosphatase were observed to be raised in diabetic rats. Diabetic rats treated with parsley demonstrated significantly lower levels of blood glucose, alanine transaminase and alkaline phosphatase. The present study suggests that parsley demonstrates a significant hepatoprotective effect in diabetic rats. Copyright © 2004 John Wiley & Sons, Ltd.

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