Dietary Palatinose and Oleic Acid Ameliorate Disorders of Glucose and Lipid Metabolism in Zucker Fatty Rats , ,3

Chicco, 2003, Muscle lipid metabolism and insulin secretion are altered in insulin-resistant rats fed a high sucrose diet, J Nutr, 133, 127, 10.1093/jn/133.1.127

Pagliassotti, 2002, Elevated basal PI 3-kinase activity and reduced insulin signaling in sucrose-induced hepatic insulin resistance, Am J Physiol Endocrinol Metab, 282, E170, 10.1152/ajpendo.2002.282.1.E170

Wylie-Rosett, 2004, Carbohydrates and increases in obesity: does the type of carbohydrate make a difference?, Obes Res, 12, 124S, 10.1038/oby.2004.277

Daly, 2003, Sugars, insulin sensitivity, and the postprandial state, Am J Clin Nutr, 78, 865S, 10.1093/ajcn/78.4.865S

Bessesen, 2001, The role of carbohydrates in insulin resistance, J Nutr, 131, 2782S, 10.1093/jn/131.10.2782S

Kawai, 1985, Changes in blood glucose and insulin after an oral palatinose administration in normal subjects, Endocrinol Jpn, 32, 933, 10.1507/endocrj1954.32.933

Kawai, 1989, Usefulness of palatinose as a caloric sweetener for diabetic patients, Horm Metab Res, 21, 338, 10.1055/s-2007-1009230

Calder, 2005, Polyunsaturated fatty acids and inflammation, Biochem Soc Trans, 33, 423, 10.1042/BST0330423

Moreno, 2003, The degree of unsaturation of dietary fatty acids and the development of atherosclerosis (review), J Nutr Biochem, 14, 182, 10.1016/S0955-2863(02)00294-2

Reaven, 1993, Effects of oleate-rich and linoleate-rich diets on the susceptibility of low density lipoprotein to oxidative modification in mildly hypercholesterolemic subjects, J Clin Invest, 91, 668, 10.1172/JCI116247

Busch, 2002, Expression profiling of palmitate- and oleate-regulated genes provides novel insights into the effects of chronic lipid exposure on pancreatic beta-cell function, Diabetes, 51, 977, 10.2337/diabetes.51.4.977

Maedler, 2003, Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function, Diabetes, 52, 726, 10.2337/diabetes.52.3.726

Hu, 2002, Optimal diets for prevention of coronary heart disease, JAMA, 288, 2569, 10.1001/jama.288.20.2569

Arai, 2004, Effect of a novel palatinose-based liquid balanced formula (MHN-01) on glucose and lipid metabolism in male Sprague-Dawley rats after short- and long-term ingestion, Metabolism, 53, 977, 10.1016/j.metabol.2004.03.004

Arai, 2007, Effects of a palatinose-based liquid diet (Inslow) on glycemic control and the second-meal effect in healthy men, Metabolism, 56, 115, 10.1016/j.metabol.2006.09.005

Zucker, 1972, Insulin and obesity in the Zucker genetically obese rat “fatty”, Endocrinology, 90, 1320, 10.1210/endo-90-5-1320

Cleary, 1980, Development of obesity in Zucker obese (fafa) rat in absence of hyperphagia, Am J Physiol, 238, E284

Johnson, 1973, Effect of early nutrition on adipose cellularity and pancreatic insulin release in the Zucker rat, J Nutr, 103, 738, 10.1093/jn/103.5.738

Folch, 1957, A simple method for the isolation and purification of total lipides from animal tissues, J Biol Chem, 226, 497, 10.1016/S0021-9258(18)64849-5

Horton, 2002, Sterol regulatory element-binding proteins: transcriptional activators of lipid synthesis, Biochem Soc Trans, 30, 1091, 10.1042/bst0301091

Joseph, 2003, LXRs: new therapeutic targets in atherosclerosis?, Curr Opin Pharmacol, 3, 192, 10.1016/S1471-4892(03)00009-2

Dahlqvist, 1963, Human intestinal disaccharidases and hereditary disaccharide intolerance. The hydrolysis of sucrose, isomaltose, palatinose (isomaltulose), and a 1,6-alpha-oligosaccharide (isomalto-oligosaccharide) preparation, J Clin Invest, 42, 556, 10.1172/JCI104744

MacDonald, 1983, The bioavailability of isomaltulose in man and rat, Nutr Rep Int, 28, 1083

Reaven, 1983, Effect of age and diet on insulin secretion and insulin action in the rat, Diabetes, 32, 175, 10.2337/diab.32.2.175

Del Zotto, 2002, Mechanisms involved in the beta-cell mass increase induced by chronic sucrose feeding to normal rats, J Endocrinol, 174, 225, 10.1677/joe.0.1740225

Pan, 1993, Dietary lipid profile is a determinant of tissue phospholipid fatty acid composition and rate of weight gain in rats, J Nutr, 123, 512, 10.1093/jn/123.3.512

Soriguer, 2000, Varying incorporation of fatty acids into phospholipids from muscle, adipose and pancreatic exocrine tissues and thymocytes in adult rats fed with diets rich in different fatty acids, Eur J Epidemiol, 16, 585, 10.1023/A:1007684808188

Kramer, 1997, Structure, function and regulation of Ca2+-sensitive cytosolic phospholipase A2 (cPLA2), FEBS Lett, 410, 49, 10.1016/S0014-5793(97)00322-0

Rao, 1993, Effect of high fat corn oil, olive oil and fish oil on phospholipid fatty acid composition in male F344 rats, Lipids, 28, 441, 10.1007/BF02535943

Chen, 2005, Activation of 12-lipoxygenase in proinflammatory cytokine-mediated beta cell toxicity, Diabetologia, 48, 486, 10.1007/s00125-005-1673-y

Prasad, 2003, Evidence that increased 12-lipoxygenase expression impairs pancreatic beta cell function and viability, Biochem Biophys Res Commun, 308, 427, 10.1016/S0006-291X(03)01418-9

Kersten, 1999, Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting, J Clin Invest, 103, 1489, 10.1172/JCI6223

Leone, 1999, A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARα-null mouse as a model of fatty acid oxidation disorders, Proc Natl Acad Sci USA, 96, 7473, 10.1073/pnas.96.13.7473

Dentin, 2005, Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation, J Clin Invest, 115, 2843, 10.1172/JCI25256

Xu, 2002, Dietary polyunsaturated fats regulate rat liver sterol regulatory element binding proteins-1 and -2 in three distinct stages and by different mechanisms, J Nutr, 132, 3333, 10.1093/jn/132.11.3333

Arkan, 2005, IKK-beta links inflammation to obesity-induced insulin resistance, Nat Med, 11, 191, 10.1038/nm1185

Cai, 2005, Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB, Nat Med, 11, 183, 10.1038/nm1166

Khovidhunkit, 2004, Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host, J Lipid Res, 45, 1169, 10.1194/jlr.R300019-JLR200

Feingold, 1995, Discordant regulation of proteins of cholesterol metabolism during the acute phase response, J Lipid Res, 36, 1474, 10.1016/S0022-2275(20)39734-0

Grunfeld, 1988, Mechanisms by which tumor necrosis factor stimulates hepatic fatty acid synthesis in vivo, J Lipid Res, 29, 1327, 10.1016/S0022-2275(20)38435-2

Feingold, 1989, Effect of tumor necrosis factor (TNF) on lipid metabolism in the diabetic rat. Evidence that inhibition of adipose tissue lipoprotein lipase activity is not required for TNF-induced hyperlipidemia, J Clin Invest, 83, 1116, 10.1172/JCI113991

Grunfeld, 1989, Effect of tumor necrosis factor administration in vivo on lipoprotein lipase activity in various tissues of the rat, J Lipid Res, 30, 579, 10.1016/S0022-2275(20)38349-8

Feingold, 1990, The effect of diet on tumor necrosis factor stimulation of hepatic lipogenesis, Metabolism, 39, 623, 10.1016/0026-0495(90)90030-G

Rivera, 2006, Feeding a corn oil/sucrose-enriched diet enhances steatohepatitis in sedentary rats, Am J Physiol Gastrointest Liver Physiol, 290, G386, 10.1152/ajpgi.00229.2005

Kanarek, 1987, Sucrose-induced obesity: effect of diet on obesity and brown adipose tissue, Am J Physiol, 253, R158

Soria, 2001, Duration of feeding on a sucrose-rich diet determines metabolic and morphological changes in rat adipocytes, J Appl Physiol, 91, 2109, 10.1152/jappl.2001.91.5.2109

Weisberg, 2003, Obesity is associated with macrophage accumulation in adipose tissue, J Clin Invest, 112, 1796, 10.1172/JCI200319246

Xu, 2003, Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance, J Clin Invest, 112, 1821, 10.1172/JCI200319451

Linton, 2004, Cyclooxygenase-2 and inflammation in atherosclerosis, Curr Opin Pharmacol, 4, 116, 10.1016/j.coph.2003.12.003

Moreno, 2001, Olive oil decreases both oxidative stress and the production of arachidonic acid metabolites by the prostaglandin G/H synthase pathway in rat macrophages, J Nutr, 131, 2145, 10.1093/jn/131.8.2145

Ghafoorunissa, 2005, Substituting dietary linoleic acid with alpha-linolenic acid improves insulin sensitivity in sucrose fed rats, Biochim Biophys Acta, 1733, 67, 10.1016/j.bbalip.2004.12.003