The Mystery of Rap1 Suppression of Oncogenic Ras
Tài liệu tham khảo
Takahashi, 2017, Phosphorylation of Rap1 by cAMP-dependent protein kinase (PKA) creates a binding site for KSR to sustain ERK activation by cAMP, J. Biol. Chem., 292, 1449, 10.1074/jbc.M116.768986
Li, 2016, Protein kinase A-independent Ras protein activation cooperates with Rap1 protein to mediate activation of the extracellular signal-regulated kinases (ERK) by cAMP, J. Biol. Chem., 291, 21584, 10.1074/jbc.M116.730978
Xu, 2018, Small GTPase Rap1A/B is required for lymphatic development and adrenomedullin-induced stabilization of lymphatic endothelial junctions, Arterioscler. Thromb. Vasc. Biol., 38, 2410, 10.1161/ATVBAHA.118.311645
Raaijmakers, 2009, Specificity in Ras and Rap signaling, J. Biol. Chem., 284, 10995, 10.1074/jbc.R800061200
Itoh, 2007, Rap1 integrates tissue polarity, lumen formation, and tumorigenic potential in human breast epithelial cells, Cancer Res., 67, 4759, 10.1158/0008-5472.CAN-06-4246
Goto, 2010, Rap1 stabilizes β-catenin and enhances β-catenin-dependent transcription and invasion in squamous cell carcinoma of the head and neck, Clin. Cancer Res., 16, 65, 10.1158/1078-0432.CCR-09-1122
Okada, 1999, The strength of interaction at the Raf cysteine-rich domain is a critical determinant of response of Raf to Ras family small GTPases, Mol. Cell. Biol., 19, 6057, 10.1128/MCB.19.9.6057
Stout, 2014, Analyzing Ras-associated cell proliferation signaling, Methods Mol. Biol., 1170, 393, 10.1007/978-1-4939-0888-2_21
Zhang, 2019, The mechanism of PI3Kα activation at the atomic level, Chem. Sci., 10, 3671, 10.1039/C8SC04498H
Xu, 2013, Dominant role of oncogene dosage and absence of tumor suppressor activity in Nras-driven hematopoietic transformation, Cancer Discov., 3, 993, 10.1158/2159-8290.CD-13-0096
Zhou, 2014, Signal integration by lipid-mediated spatial cross talk between Ras nanoclusters, Mol. Cell. Biol., 34, 862, 10.1128/MCB.01227-13
Fischer, 2007, B- and C-RAF display essential differences in their binding to Ras: the isotype-specific N terminus of B-RAF facilitates Ras binding, J. Biol. Chem., 282, 26503, 10.1074/jbc.M607458200
Williams, 2000, Elucidation of binding determinants and functional consequences of Ras/Raf-cysteine-rich domain interactions, J. Biol. Chem., 275, 22172, 10.1074/jbc.M000397200
Lee, 2019, High-throughput single-particle tracking reveals nested membrane domains that dictate KRasG12D diffusion and trafficking, eLife, 8, 10.7554/eLife.46393
Wang, 2013, Mutant N-RAS protects colorectal cancer cells from stress-induced apoptosis and contributes to cancer development and progression, Cancer Discov., 3, 294, 10.1158/2159-8290.CD-12-0198
Cerami, 2012, The cBio Cancer Genomics Portal: an open platform for exploring multidimensional cancer genomics data, Cancer Discov., 2, 401, 10.1158/2159-8290.CD-12-0095