Translational Neurodegeneration
SCIE-ISI SCOPUS (2012-2025)
2047-9158
Cơ quản chủ quản: BMC , BioMed Central Ltd.
Lĩnh vực:
Neurology (clinical)Cognitive NeuroscienceCellular and Molecular Neuroscience
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The transition metal copper enhances amyloid β aggregation and neurotoxicity,
and in models of concomitant amyloid and tau pathology, copper also promotes tau
aggregation. Since it is not clear if the effects of environmental copper upon
tau pathology are dependent on the presence of pathological amyloid β, we tested
the effects of copper overload and complexing in disease models which lack
pathol...