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ESCI-ISI SCOPUS (2016-2025)
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Cơ quản chủ quản: Springer Science and Business Media Deutschland GmbH , Springer Nature
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Radiology, Nuclear Medicine and ImagingAnalytical ChemistryPharmacologyPharmacology (medical)
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Các bài báo tiêu biểu
Targeting fibroblast activation protein (FAP): next generation PET radiotracers using squaramide coupled bifunctional DOTA and DATA5m chelators
Tập 5 Số 1 - 2020
Abstract Background Fibroblast activation protein (FAP) is a proline selective
serine protease that is overexpressed in tumor stroma and in lesions of many
other diseases that are characterized by tissue remodeling. In 2014, a most
potent FAP-inhibitor (referred to as UAMC1110) with low nanomolar FAP-affinity
and high selectivity toward related enzymes such as prolyl oligopeptidase (PREP)
and the ...
Cyclotron-based production of 68Ga, [68Ga]GaCl3, and [68Ga]Ga-PSMA-11 from a liquid target
- 2020
AbstractPurposeTo optimize the direct production of68Ga on a cyclotron, via
the68Zn(p,n)68Ga reaction using a liquid cyclotron target. We Investigated the
yield of cyclotron-produced68Ga, extraction of [68Ga]GaCl3and subsequent
[68Ga]Ga-PSMA-11 labeling using an automated synthesis
module.MethodsIrradiations of a 1.0 M solution of [68Zn]Zn(NO3)2in dilute
(0.2–0.3 M) HNO3were conducted using GE PET...
Radiolabeled nanomaterials for biomedical applications: radiopharmacy in the era of nanotechnology
Tập 7 Số 1
AbstractBackgroundRecent advances in nanotechnology have offered new hope for
cancer detection, prevention, and treatment. Nanomedicine, a term for the
application of nanotechnology in medical and health fields, uses nanoparticles
for several applications such as imaging, diagnostic, targeted cancer therapy,
drug and gene delivery, tissue engineering, and theranostics.ResultsHere, we
overview the ...
Development and implementation of ISAR, a new synthesis platform for radiopharmaceutical production
Tập 4 Số 1 - 2019
Abstract Background PET radiopharmaceutical development and the implementation
of a production method on a synthesis module is a complex and time-intensive
task since new synthesis methods must be adapted to the confines of the
synthesis platform in use. Commonly utilized single fluid bus architectures put
multiple constraints on synthesis planning and execution, while conventional
microfluidic so...
Automated, cassette-based isolation and formulation of high-purity [61Cu]CuCl2 from solid Ni targets
- 2020
Abstract Background A need for improved, cassette-based automation of 61Cu
separation from irradiated Ni targets was identified given the growing interest
in theranostics, and generally lengthy separation chemistries for 64Cu/64Ni,
upon which 61Cu chemistry is often based. Methods A method for separating 61Cu
from irradiated natNi targets was therefore developed, with provision for target
recyclin...
Advances in the automated synthesis of 6-[18F]Fluoro-L-DOPA
Tập 6 Số 1
AbstractThe neurotracer 6-[18F]FDOPA has been, for many years, a powerful tool
in PET imaging of neuropsychiatric diseases, movement disorders and brain
malignancies. More recently, it also demonstrated good results in the diagnosis
of other malignancies such as neuroendocrine tumours, pheochromocytoma or
pancreatic adenocarcinoma.The multiple clinical applications of this tracer
fostered a very s...