Design and synthesis of dipeptide mimetics of the brain-derived neurotrophic factor Tập 38 - Trang 243-252 - 2012
T. A. Gudasheva, A. V. Tarasyuk, S. V. Pomogaibo, I. O. Logvinov, P. Yu. Povarnina, T. A. Antipova, S. B. Seredenin
Low-molecular-weight mimetics of loops 1 and 4 of the brain-derived neurotrophic
factor (BDNF) have been designed and synthesized. The compounds represent
monomeric and dimeric amides of N-acyldipeptides. Their dipeptide fragments
coincide in sequence with the central regions of beta-turns of the corresponding
neurotrophin loops, and acyl groups are the bioesosteres of preceding amino acid
residue... hiện toàn bộ
Synthesis and antimicrobial and toxic properties of novel 1,3-bis(alkyl)-6-methyluracil derivatives containing 1,2,3- and 1,2,4-triazolium fragments - 2017
Alexandra D. Voloshina, В. Э. Семенов, А. С. Стробыкина, Natalia Kulik, E. S. Krylova, В. В. Зобов, В. С. Резник
The synthesis and hepatoprotective activity of esters of the lupane group triterpenoids Tập 26 Số 3 - Trang 192-200 - 2000
О. Б. Флехтер, Л. Т. Карачурина, Vladimir Poroikov, L. P. Nigmatullina, Л. А. Балтина, Ф. С. Зарудий, В. А. Давыдова, Л. В. Спирихин, И. П. Байкова, Ф. З. Галин, Г. А. Толстиков
STAT1: A many-sided transcription factor Tập 36 - Trang 11-23 - 2010
I. A. Kostanyan, A. V. Vonarshenko, V. M. Lipkin
The cell homeostasis is regulated by numerous signaling proteins. Their common
task is to process extracellular signals by triggering cascades of intracellular
reactions leading to modulation of down-stream gene activities. One of the
important signaling pathways is represented by the STAT family, comprising seven
participants. Various STATs operate as the powerful transcription factors
delivering... hiện toàn bộ