Soft tissue sarcoma across the age spectrum: A population‐based study from the surveillance epidemiology and end results database Tập 57 Số 6 - Trang 943-949 - 2011
Andrea Ferrari, Iyad Sultan, Tseng Tien Huang, Carlos Rodríguez‐Galindo, Ahmad Shehadeh, Cristina Meazza, Kirsten K. Ness, Michela Casanova, Sheri L. Spunt
AbstractBackgroundSoft tissue sarcomas (STS) are a heterogeneous group of
mesenchymal malignancies that occur throughout the lifespan. The impact of age
on disease features and outcome is unclear.MethodsWe analyzed the clinical
features and outcome of all STS cases registered between 1973 and 2006 in the
SEER database.ResultsThere were 48,012 cases that met the selection criteria.
Individuals less... hiện toàn bộ
Uncommon histiocytic disorders: The non‐Langerhans cell histiocytoses Tập 45 Số 3 - Trang 256-264 - 2005
Sheila Weitzman, Ronald Jaffe
AbstractBackgroundHistiocytic disorders are currently identified by their
component cells. The non‐Langerhans Cell Histiocytoses (non‐LCH) are a group of
disorders defined by the accumulation of histiocytes that do not meet the
phenotypic criteria for the diagnosis of Langerhans cells (LCs). The non‐LCH
consist of a long list of diverse disorders which have been difficult to
categorize. A conceptu... hiện toàn bộ
Successful treatment of a child with t(15;19)‐positive tumor Tập 49 Số 7 - Trang 1015-1017 - 2007
Fredrik Mertens, Thomas Wiebe, Catharina Adlercreutz, Nils Mandahl, Christopher A. French
AbstractA subset of poorly differentiated carcinomas is characterized by the
translocation t(15;19)(q13;p13), resulting in a BRD4/NUT fusion gene. Typically,
this tumor affects children or young adults, with a predilection for midline
head and neck or thoracic structures. The clinical course is invariably fatal,
in spite of intensive chemotherapy and radiotherapy. We here present the
successful tr... hiện toàn bộ
Effect of childhood cancer treatment on fertility markers in adult male long‐term survivors Tập 52 Số 1 - Trang 108-112 - 2009
Niels J. van Casteren, G Linden, F.G.A.J. Hakvoort-Cammel, Karel Hählen, Gert R. Dohle, Marry M. van den Heuvel‐Eibrink
AbstractBackgroundAlthough it is accepted that pediatric cancer treatment
harbors a risk of gonadal damage, large cohort studies using up‐to‐date
fertility markers are lacking.ProcedureThe aim of our study was to evaluate the
gonadal toxicity of childhood cancer treatment using fertility markers. We
included 248 adult male long‐term survivors of childhood cancer. Median age at
diagnosis: 5 years, ... hiện toàn bộ
Epidemiology of childhood acute myeloid leukemia Tập 60 Số 5 - Trang 728-733 - 2013
Susan E. Puumala, Julie A. Ross, Richard Aplenc, Logan G. Spector
AbstractAlthough leukemia is the most common childhood cancer diagnosis, the
subtype, acute myeloid leukemia (AML), is less common and fewer etiologic
studies exist. This review summarizes the major risk factors for AML. We
searched the literature using PubMed for articles on childhood AML and reviewed
180 articles. While few risk factors are definitive, we identified several with
consistent evide... hiện toàn bộ
Enalapril and hydroxyurea therapy for children with sickle nephropathy Tập 45 Số 7 - Trang 982-985 - 2005
Courtney D. Fitzhugh, Delbert R. Wigfall, Russell E. Ware
AbstractProteinuria in children with sickle cell anemia (SCA) is an early sign
of sickle nephropathy, and portends the development of nephrotic syndrome and
chronic renal failure. Enalapril has been shown to reduce proteinuria in adult
patients with SCA, but the potential benefits of hydroxyurea in this clinical
setting have not been reported. A single institution retrospective analysis was
perfor... hiện toàn bộ
Impact of telemedicine on pediatric neuro‐oncology in a developing country: The Jordanian‐Canadian experience Tập 48 Số 1 - Trang 39-43 - 2007
Ibrahim Qaddoumi, Asem Mansour, Awni Musharbash, James M. Drake, Maisa Swaidan, Tarık Tihan, Éric Bouffet
AbstractBackgroundTelemedicine is widely used in industrialized countries for
educational purposes. Twinning experiences using telemedicine between
institutions in industrialized and developing countries (DC) have been limited.
Pediatric neuro‐oncology is a complex multidisciplinary discipline that is
underserved in most of DC and provides a model to test the feasibility of such
tool for twinning ... hiện toàn bộ
Prevalence of Metastasis at Diagnosis of Osteosarcoma: An International Comparison Tập 63 Số 6 - Trang 1006-1011 - 2016
Tracy A. Marko, Brandon J. Diessner, Logan G. Spector
BackgroundOsteosarcoma (OS) is the most common primary malignant bone tumor in
many countries, with metastatic disease responsible for most patient deaths.
This study compares the prevalence of metastatic OS at diagnosis across
countries to inform the critical question of whether diagnostic delay or tumor
biology drives metastases development prior to diagnosis.ProcedureA literature
search of the ... hiện toàn bộ
Epidemiology of bone tumours in children and young adults Tập 53 Số 6 - Trang 941-952 - 2009
Rachel Eyre, Richard Feltbower, Emmanuel Mubwandarikwa, Tim Eden, Richard McNally
AbstractAlthough the epidemiology of malignant bone tumours in children and
young adults has been explored, no definitive causation of any specific tumour
has yet been identified. We performed a literature review (1970–2008) to find
all papers covering possible aetiological factors involved in the development of
bone tumours in children and young adults. Several associations have been
reported wit... hiện toàn bộ