Resolution of chronic hypoxemia in pediatric sickle cell patients after treatment with hydroxyureaPediatric Blood and Cancer - Tập 50 Số 6 - Trang 1258-1260 - 2008
Sharon Singh, Anastassios C. Koumbourlis, Banu Aygün
AbstractChronic hypoxemia is a common manifestation among patients with sickle
cell anemia (SCA) who develop chronic lung disease. We report the beneficial
effect of hydroxyurea on chronic hypoxemia in three pediatric patients with SCA
and recurrent episodes of acute chest syndrome (ACS). All three patients
improved rapidly after they were treated with hydroxyurea despite having
additional risk fa... hiện toàn bộ
Enalapril and hydroxyurea therapy for children with sickle nephropathyPediatric Blood and Cancer - Tập 45 Số 7 - Trang 982-985 - 2005
Courtney D. Fitzhugh, Delbert R. Wigfall, Russell E. Ware
AbstractProteinuria in children with sickle cell anemia (SCA) is an early sign
of sickle nephropathy, and portends the development of nephrotic syndrome and
chronic renal failure. Enalapril has been shown to reduce proteinuria in adult
patients with SCA, but the potential benefits of hydroxyurea in this clinical
setting have not been reported. A single institution retrospective analysis was
perfor... hiện toàn bộ
Epidemiology of childhood acute myeloid leukemiaPediatric Blood and Cancer - Tập 60 Số 5 - Trang 728-733 - 2013
Susan E. Puumala, Julie A. Ross, Richard Aplenc, Logan G. Spector
AbstractAlthough leukemia is the most common childhood cancer diagnosis, the
subtype, acute myeloid leukemia (AML), is less common and fewer etiologic
studies exist. This review summarizes the major risk factors for AML. We
searched the literature using PubMed for articles on childhood AML and reviewed
180 articles. While few risk factors are definitive, we identified several with
consistent evide... hiện toàn bộ
Prevalence of Metastasis at Diagnosis of Osteosarcoma: An International ComparisonPediatric Blood and Cancer - Tập 63 Số 6 - Trang 1006-1011 - 2016
Tracy A. Marko, Brandon J. Diessner, Logan G. Spector
BackgroundOsteosarcoma (OS) is the most common primary malignant bone tumor in
many countries, with metastatic disease responsible for most patient deaths.
This study compares the prevalence of metastatic OS at diagnosis across
countries to inform the critical question of whether diagnostic delay or tumor
biology drives metastases development prior to diagnosis.ProcedureA literature
search of the ... hiện toàn bộ
Self‐limiting sternal tumors of childhood (SELSTOC)Pediatric Blood and Cancer - Tập 55 Số 1 - Trang 81-84 - 2010
M.L. te Winkel, M Lequin, John R. de Bruyn, Cornelis P. van de Ven, Ronald R. de Krijger, Rob Pieters, Marry M. van den Heuvel‐Eibrink
AbstractBackgroundBecause a sternal mass is often alarming, it is important to
identify the clinical features of benign processes.ProcedureData on clinical
presentation, diagnostics, treatment and outcome of pediatric patients
presenting with a sternal tumor between 2001 and 2009 were collected from
medical records.ResultsAmong the 1,700 children who were referred to our
pediatric‐oncology center,... hiện toàn bộ