Anders Andersen, David J. Warren, Paal Brunsvig, Steinar Aamdal, Gunnar B. Kristensen, Harald Olsen
Abstract Background The taxanes paclitaxel and docetaxel have traditionally been
used in high doses every third week in the treatment of cancer. Lately there has
been a trend towards giving weekly low doses to improve the therapeutic index.
This article describes the development of high performance liquid
chromatographic (HPLC) methods suitable for monitoring taxane levels in
patients, focusing on... hiện toàn bộ