Omega-3 and omega-6 polyunsaturated fatty acids: Dietary sources, metabolism, and significance — A review

Life Sciences - Tập 203 - Trang 255-267 - 2018
Ramesh Kumar Saini1, Young-Soo Keum1
1Department of Crop Science, Konkuk University, Seoul, 143-701, Republic of Korea

Tài liệu tham khảo

Bazinet, 2014, Polyunsaturated fatty acids and their metabolites in brain function and disease, Nat. Rev. Neurosci., 15, 771, 10.1038/nrn3820

Dennis, 2015, Eicosanoid storm in infection and inflammation, Nat. Rev. Immunol., 15, 511, 10.1038/nri3859

Fredman, 2017, Boosting inflammation resolution in atherosclerosis: the next frontier for therapy, Am. J. Pathol., 187, 1211, 10.1016/j.ajpath.2017.01.018

Serhan, 2005, Resolution of inflammation: the beginning programs the end, Nat. Immunol., 6, 1191, 10.1038/ni1276

Del Gobbo, 2016, ω−3 polyunsaturated fatty acid biomarkers and coronary heart disease: pooling project of 19 cohort studies, JAMA Intern. Med., 176, 1155, 10.1001/jamainternmed.2016.2925

Kang, 2012, The role of the tissue omega-6/omega-3 fatty acid ratio in regulating tumor angiogenesis, Cancer Metastasis Rev., 32, 201, 10.1007/s10555-012-9401-9

Moghadasian, 2008, Advances in dietary enrichment with N−3 fatty acids, Crit. Rev. Food Sci. Nutr., 48, 402, 10.1080/10408390701424303

Parmentier, 2007, Polar lipids: n−3 PUFA carriers for membranes and brain: nutritional interest and emerging processes, Ol. Corps Gras Lipides, 14, 224, 10.1051/ocl.2007.0127

Subbaiah, 2016, Enhanced incorporation of dietary DHA into lymph phospholipids by altering its molecular carrier, Biochim. Biophys. Acta Mol. Cell Biol. Lipids, 1861 (, 723, 10.1016/j.bbalip.2016.05.002

Yoshinaga, 2015, Differential effects of triacylglycerol positional isomers containing n−3 series highly unsaturated fatty acids on lipid metabolism in C57BL/6J mice, J. Nutr. Biochem., 26, 57, 10.1016/j.jnutbio.2014.09.004

Sugasini, 2017, Dietary docosahexaenoic acid (DHA) as lysophosphatidylcholine, but not as free acid, enriches brain DHA and improves memory in adult mice, Sci. Rep., 7, 10.1038/s41598-017-11766-0

Barceló-Coblijn, 2009, Alpha-linolenic acid and its conversion to longer chain n−3 fatty acids: benefits for human health and a role in maintaining tissue n−3 fatty acid levels, Prog. Lipid Res., 48, 355, 10.1016/j.plipres.2009.07.002

Ruiz-Lopez, 2014, Modifying the lipid content and composition of plant seeds: engineering the production of LC-PUFA, Appl. Microbiol. Biotechnol., 99, 143, 10.1007/s00253-014-6217-2

Abedi, 2014, Long-chain polyunsaturated fatty acid sources and evaluation of their nutritional and functional properties, Food Sci. Nutr., 2, 443, 10.1002/fsn3.121

Schmitz, 2008, The opposing effects of n−3 and n−6 fatty acids, Prog. Lipid Res., 47, 147, 10.1016/j.plipres.2007.12.004

Simopoulos, 2006, Evolutionary aspects of diet, the omega-6/omega-3 ratio and genetic variation: nutritional implications for chronic diseases, Biomed Pharmacother, 60, 502, 10.1016/j.biopha.2006.07.080

Ailhaud, 2004, Fatty acid composition of fats is an early determinant of childhood obesity: a short review and an opinion, Obes. Rev., 5, 21, 10.1111/j.1467-789X.2004.00121.x

Blasbalg, 2011, Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century, Am. J. Clin. Nutr., 93, 950, 10.3945/ajcn.110.006643

Micha, 2014, Global, regional, and national consumption levels of dietary fats and oils in 1990 and 2010: a systematic analysis including 266 country-specific nutrition surveys, BMJ, 348, 10.1136/bmj.g2272

Stark, 2016, Global survey of the omega-3 fatty acids, docosahexaenoic acid and eicosapentaenoic acid in the blood stream of healthy adults, Prog. Lipid Res., 63, 132, 10.1016/j.plipres.2016.05.001

Sioen, 2017, Systematic review on N−3 and N−6 polyunsaturated fatty acid intake in European countries in light of the current recommendations - focus on specific population groups, Ann. Nutr. Metab., 70, 39, 10.1159/000456723

Gebauer, 2006, n−3 fatty acid dietary recommendations and food sources to achieve essentiality and cardiovascular benefits, Am. J. Clin. Nutr., 83, 1526S, 10.1093/ajcn/83.6.1526S

von Schacky, 2007, Cardiovascular benefits of omega-3 fatty acids, Cardiovasc. Res., 73, 310, 10.1016/j.cardiores.2006.08.019

Gellert, 2017, Low long chain omega-3 fatty acid status in middle-aged women, Prostaglandins Leukot. Essent. Fat. Acids, 117, 54, 10.1016/j.plefa.2017.01.009

Giltay, 2004, Docosahexaenoic acid concentrations are higher in women than in men because of estrogenic effects, Am. J. Clin. Nutr., 80, 1167, 10.1093/ajcn/80.5.1167

Harauma, 2017, The essentiality of arachidonic acid in addition to docosahexaenoic acid for brain growth and function, Prostaglandins Leukot. Essent. Fat. Acids, 116, 9, 10.1016/j.plefa.2016.11.002

Zhou, 2006, Vitamin A deficiency enhances docosahexaenoic and Osbond acids in liver of rats fed an α-linoleic acid-adequate diet, Lipids, 41, 213, 10.1007/s11745-006-5090-x

Ghasemifard, 2014, Omega-3 long chain fatty acid “bioavailability”: a review of evidence and methodological considerations, Prog. Lipid Res., 56, 92, 10.1016/j.plipres.2014.09.001

Ulven, 2011, Metabolic effects of krill oil are essentially similar to those of fish oil but at lower dose of EPA and DHA, in healthy volunteers, Lipids, 46, 37, 10.1007/s11745-010-3490-4

Ganesh, 2016, A review: supplementation of foods with essential fatty acids—can it turn a breeze without further ado?, Crit. Rev. Food Sci. Nutr., 56, 1417, 10.1080/10408398.2013.765383

Garg, 2006, Means of delivering recommended levels of long chain n−3 polyunsaturated fatty acids in human diets, J. Food Sci., 71, R66, 10.1111/j.1750-3841.2006.00033.x

Kanakri, 2017, A reduced cost strategy for enriching chicken meat with omega-3 long chain polyunsaturated fatty acids using dietary flaxseed oil, Br. Poult. Sci., 10.1080/00071668.2017.1293798

Benbrook, 2013, Organic production enhances milk nutritional quality by shifting fatty acid composition: a United States–wide, 18-month study, PLoS One, 8, 10.1371/journal.pone.0082429

Sprague, 2016, Impact of sustainable feeds on omega-3 long-chain fatty acid levels in farmed Atlantic salmon, 2006–2015, Sci. Rep., 6, 10.1038/srep21892

Betancor, 2015, A nutritionally-enhanced oil from transgenic Camelina sativa effectively replaces fish oil as a source of eicosapentaenoic acid for fish, Sci. Rep., 5, 10.1038/srep08104

Harris, 2008, Stearidonic acid-enriched soybean oil increased the omega-3 index, an emerging cardiovascular risk marker, Lipids, 43, 805, 10.1007/s11745-008-3215-0

Bakry, 2016, Microencapsulation of oils: a comprehensive review of benefits, techniques, and applications, Compr. Rev. Food Sci. Food Saf., 15, 143, 10.1111/1541-4337.12179

Ruiz, 2017, Encapsulation of vegetable oils as source of omega-3 fatty acids for enriched functional foods, Crit. Rev. Food Sci. Nutr., 57, 1423, 10.1080/10408398.2014.1002906

Stark, 2016, Past and present insights on alpha-linolenic acid and the omega-3 fatty acid family, Crit. Rev. Food Sci. Nutr., 56, 2261, 10.1080/10408398.2013.828678

Kitajka, 2002, The role of n−3 polyunsaturated fatty acids in brain: modulation of rat brain gene expression by dietary n−3 fatty acids, Proc. Natl. Acad. Sci. U. S. A., 99, 2619, 10.1073/pnas.042698699

Song, 2016, The role of omega-3 polyunsaturated fatty acids eicosapentaenoic and docosahexaenoic acids in the treatment of major depression and Alzheimer's disease: acting separately or synergistically?, Prog. Lipid Res., 62, 41, 10.1016/j.plipres.2015.12.003

Deacon, 2017, Omega 3 polyunsaturated fatty acids and the treatment of depression, Crit. Rev. Food Sci. Nutr., 57, 212, 10.1080/10408398.2013.876959

Johnson, 2017, Omega 3/6 fatty acids for reading in children: a randomized, double-blind, placebo-controlled trial in 9-year-old mainstream schoolchildren in Sweden, J. Child Psychol. Psychiatry, 58, 83, 10.1111/jcpp.12614

Colussi, 2017, Impact of omega-3 polyunsaturated fatty acids on vascular function and blood pressure: relevance for cardiovascular outcomes, Nutr. Metab. Cardiovasc. Dis., 27, 191, 10.1016/j.numecd.2016.07.011

Tortosa-Caparrós, 2017, Anti-inflammatory effects of omega 3 and omega 6 polyunsaturated fatty acids in cardiovascular disease and metabolic syndrome, Crit. Rev. Food Sci. Nutr., 57, 3421, 10.1080/10408398.2015.1126549

Hu, 2002, Fish and omega-3 fatty acid intake and risk of coronary heart disease in women, JAMA, 287, 1815, 10.1001/jama.287.14.1815

Ramprasath, 2012, Decreased plasma cholesterol concentrations after PUFA-rich diets are not due to reduced cholesterol absorption/synthesis, Lipids, 47, 1063, 10.1007/s11745-012-3708-8

Sugiyama, 2008, Eicosapentaenoic acid lowers plasma and liver cholesterol levels in the presence of peroxisome proliferators-activated receptor alpha, Life Sci., 83, 19, 10.1016/j.lfs.2008.04.011

Vaidya, 2015, Arachidonic acid has a dominant effect to regulate lipogenic genes in 3T3-L1 adipocytes compared to omega-3 fatty acids, Food Nutr. Res., 59, 10.3402/fnr.v59.25866

Simopoulos, 2010, Genetic variants in the metabolism of omega-6 and omega-3 fatty acids: their role in the determination of nutritional requirements and chronic disease risk, Exp. Biol. Med., 235, 785, 10.1258/ebm.2010.009298

Kimura, 2007, Meat, fish and fat intake in relation to subsite-specific risk of colorectal cancer: the Fukuoka Colorectal Cancer Study, Cancer Sci., 98, 590, 10.1111/j.1349-7006.2007.00425.x

Zheng, 2013, Intake of fish and marine n−3 polyunsaturated fatty acids and risk of breast cancer: meta-analysis of data from 21 independent prospective cohort studies, BMJ, 346, f3706, 10.1136/bmj.f3706

Williams, 2011, A high ratio of dietary n−6/n−3 polyunsaturated fatty acids is associated with increased risk of prostate cancer, Nutr. Res., 31, 1, 10.1016/j.nutres.2011.01.002

Hooper, 2006, Risks and benefits of omega 3 fats for mortality, cardiovascular disease, and cancer: systematic review, BMJ, 332, 752, 10.1136/bmj.38755.366331.2F

El-Sayed, 2017, Effect of the types of dietary fats and non-dietary oils on bone metabolism, Crit. Rev. Food Sci. Nutr., 57, 653, 10.1080/10408398.2014.914889

Griel, 2007, An increase in dietary n−3 fatty acids decreases a marker of bone resorption in humans, Nutr. J., 6, 10.1186/1475-2891-6-2

Goupil, 2015, Angiotensin II type I and prostaglandin F2α receptors cooperatively modulate signaling in vascular smooth muscle cells, J. Biol. Chem., 290, 3137, 10.1074/jbc.M114.631119

Morimoto, 2014, Prostaglandin E2–EP3 signaling induces inflammatory swelling by mast cell activation, J. Immunol., 192, 1130, 10.4049/jimmunol.1300290

Harmon, 2010, Pharmacological correction of a defect in PPAR-γ signaling ameliorates disease severity in Cftr-deficient mice, Nat. Med., 16, 313, 10.1038/nm.2101

Taylor-Clark, 2008, Prostaglandin-induced activation of nociceptive neurons via direct interaction with transient receptor potential A1 (TRPA1), Mol. Pharmacol., 73, 274, 10.1124/mol.107.040832

Tull, 2009, Omega-3 fatty acids and inflammation: novel interactions reveal a new step in neutrophil recruitment, PLoS Biol., 7, 10.1371/journal.pbio.1000177

Taketomi, 2013, Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis, Nat. Immunol., 14, 554, 10.1038/ni.2586

Moos, 2008, Cysteinyl leukotriene 2 receptor-mediated vascular permeability via transendothelial vesicle transport, FASEB J., 22, 4352, 10.1096/fj.08-113274

Bachi, 2009, Leukotriene B4 creates a favorable microenvironment for murine melanoma growth, Mol. Cancer Res., 7, 1417, 10.1158/1541-7786.MCR-09-0038

Lämmermann, 2013, Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo, Nature, 498, 371, 10.1038/nature12175

O'Sullivan, 2007, Aromatic lipoxin A4 and lipoxin B4 analogues display potent biological activities, J. Med. Chem., 50, 5894, 10.1021/jm060270d

Ohnishi, 2013, Eicosapentaenoic acid (EPA) reduces cardiovascular events: relationship with the EPA/arachidonic acid ratio, J. Atheroscler. Thromb., 20, 861, 10.5551/jat.18002

Hegde, 2011, Δ12-prostaglandin J3, an omega-3 fatty acid–derived metabolite, selectively ablates leukemia stem cells in mice, Blood, 118, 6909, 10.1182/blood-2010-11-317750

Arita, 2005, Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis, Proc. Natl. Acad. Sci. U. S. A., 102, 7671, 10.1073/pnas.0409271102

Haworth, 2008, Resolvin E1 regulates interleukin 23, interferon-γ and lipoxin A4 to promote the resolution of allergic airway inflammation, Nat. Immunol., 9, 873, 10.1038/ni.1627

Tjonahen, 2006, Resolvin E2: identification and anti-inflammatory actions: pivotal role of human 5-lipoxygenase in resolvin E series biosynthesis, Chem. Biol., 13, 1193, 10.1016/j.chembiol.2006.09.011

Oh, 2012, Resolvin E2 formation and impact in inflammation resolution, J. Immunol., 188, 4527, 10.4049/jimmunol.1103652

Serhan, 2012, Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain, FASEB J., 26, 1755, 10.1096/fj.11-201442

Hellmann, 2011, Resolvin D1 decreases adipose tissue macrophage accumulation and improves insulin sensitivity in obese-diabetic mice, FASEB J., 25, 2399, 10.1096/fj.10-178657

Chiang, 2015, Identification of resolvin D2 receptor mediating resolution of infections and organ protection, J. Exp. Med., 212, 1203, 10.1084/jem.20150225

Winkler, 2016, Resolvin D4 stereoassignment and its novel actions in host protection and bacterial clearance, Sci. Rep., 6, 10.1038/srep18972

White, 2014, Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis, Nat. Med., 20, 664, 10.1038/nm.3549

Schwab, 2007, Resolvin E1 and protectin D1 activate inflammation-resolution programmes, Nature, 447, 869, 10.1038/nature05877