Eicosapentaenoic acid regulates brown adipose tissue metabolism in high-fat-fed mice and in clonal brown adipocytes

The Journal of Nutritional Biochemistry - Tập 39 - Trang 101-109 - 2017
Mandana Pahlavani1,2, Fitia Razafimanjato1, Latha Ramalingam1,2, Nishan S. Kalupahana1,2,3, Hanna Moussa2,4, Shane Scoggin1, Naima Moustaid-Moussa1,2
1Department of Nutritional Sciences, Texas Tech University, Lubbock, TX
2Obesity Research Cluster, Texas Tech University, Lubbock, TX
3Department of Physiology, University of Peradeniya, Peradeniya, Sri Lanka
4Department of Mechanical Engineering, Texas Tech University, Lubbock, TX

Tài liệu tham khảo

Ogden, 2014, Prevalence of childhood and adult obesity in the United States, 2011–2012, JAMA, 311, 806, 10.1001/jama.2014.732 Kalupahana, 2011, (n-3) fatty acids alleviate adipose tissue inflammation and insulin resistance: mechanistic insights, Adv Nutr, 2, 304, 10.3945/an.111.000505 Cao, 2014, Adipocytokines in obesity and metabolic disease, J Endocrinol, 220, T47, 10.1530/JOE-13-0339 Sidossis, 2015, Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis, J Clin Invest, 125, 478, 10.1172/JCI78362 Harms, 2013, Brown and beige fat: development, function and therapeutic potential, Nat Med, 19, 1252, 10.1038/nm.3361 Pfeifer, 2015, Brown, beige, and white: the new color code of fat and its pharmacological implications, Annu Rev Pharmacol Toxicol, 55, 207, 10.1146/annurev-pharmtox-010814-124346 Kuhn, 2012, Brown, white, beige: the color of fat and new therapeutic perspectives for obesity, Ann Endocrinol (Paris), S2, 10.1016/S0003-4266(12)70009-4 Poher, 2015, Brown adipose tissue activity as a target for the treatment of obesity/insulin resistance, Front Physiol, 6, 10.3389/fphys.2015.00004 Stier, 2014, Mitochondrial uncoupling prevents cold-induced oxidative stress: a case study using UCP1 knockout mice, J Exp Biol, 217, 624, 10.1242/jeb.092700 Chechi, 2014, Brown adipose tissue as an anti-obesity tissue in humans, Obes Rev, 15, 92, 10.1111/obr.12116 Wortman, 2009, n3 and n6 polyunsaturated fatty acids differentially modulate prostaglandin E secretion but not markers of lipogenesis in adipocytes, Nutr Metab (Lond), 6, 5, 10.1186/1743-7075-6-5 Whelan, 2006, Innovative dietary sources of n-3 fatty acids, Annu Rev Nutr, 26, 75, 10.1146/annurev.nutr.25.050304.092605 Davis, 2003, Achieving optimal essential fatty acid status in vegetarians: current knowledge and practical implications, Am J Clin Nutr, 78, 640s, 10.1093/ajcn/78.3.640S Kalupahana, 2010, Eicosapentaenoic acid prevents and reverses insulin resistance in high-fat diet-induced obese mice via modulation of adipose tissue inflammation, J Nutr, 140, 1915, 10.3945/jn.110.125732 Murumalla, 2012, Fatty acids do not pay the toll: effect of SFA and PUFA on human adipose tissue and mature adipocytes inflammation, Lipids Health Dis, 11, 175, 10.1186/1476-511X-11-175 Takahashi, 2000, Dietary n-3 fatty acids affect mRNA level of brown adipose tissue uncoupling protein 1, and white adipose tissue leptin and glucose transporter 4 in the rat, Br J Nutr, 84, 175, 10.1017/S0007114500001409 Flachs, 2009, Cellular and molecular effects of n-3 polyunsaturated fatty acids on adipose tissue biology and metabolism, Clin Sci (Lond), 116, 1, 10.1042/CS20070456 Cao, 2004, p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene, Mol Cell Biol, 24, 3057, 10.1128/MCB.24.7.3057-3067.2004 Kumar, 2009, Liver X receptor is a regulator of orphan nuclear receptor NOR-1 gene transcription in adipocytes, Int J Obes (Lond), 33, 519, 10.1038/ijo.2009.32 Wikstrom, 2014, Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure, EMBO J, 33, 418 Aguilar, 2015, Prevalence of the metabolic syndrome in the United States, 2003–2012, JAMA, 313, 1973, 10.1001/jama.2015.4260 Johnson, 2015, Nutrition and metabolic correlates of obesity and inflammation: clinical considerations, J Nutr, 145, 1131s, 10.3945/jn.114.200758 Kalupahana, 2012, Immunity as a link between obesity and insulin resistance, Mol Aspects Med, 33, 26, 10.1016/j.mam.2011.10.011 Ogden, 2014, Prevalence of obesity in the United States, JAMA, 312, 189, 10.1001/jama.2014.6228 Lee, 2013, Obesity, inflammation and diet, Pediatr Gastroenterol Hepatol Nutr, 16, 143, 10.5223/pghn.2013.16.3.143 Bartelt, 2014, Adipose tissue browning and metabolic health, Nat Rev Endocrinol, 10, 24, 10.1038/nrendo.2013.204 Wu, 2013, Adaptive thermogenesis in adipocytes: is beige the new brown?, Genes Dev, 27, 234, 10.1101/gad.211649.112 Bargut, 2015, Mice fed fish oil diet and upregulation of brown adipose tissue thermogenic markers, Eur J Nutr, 1 de Castro, 2015, Dietary docosahexaenoic acid and eicosapentaenoic acid influence liver triacylglycerol and insulin resistance in rats fed a high-fructose diet, Mar Drugs, 13, 1864, 10.3390/md13041864 Gerling, 2014, Variable effects of 12 weeks of omega-3 supplementation on resting skeletal muscle metabolism, Appl Physiol Nutr Metab, 39, 1083, 10.1139/apnm-2014-0049 Zhao, 2014, Eicosapentaenoic acid promotes thermogenic and fatty acid storage capacity in mouse subcutaneous adipocytes, Biochem Biophys Res Commun, 450, 1446, 10.1016/j.bbrc.2014.07.010 Sneddon, 2009, Dietary supplementation with conjugated linoleic acid plus n-3 polyunsaturated fatty acid increases food intake and brown adipose tissue in rats, Nutrients, 1, 178, 10.3390/nu1020178 Lee, 2014, Functional thermogenic beige adipogenesis is inducible in human neck fat, Int J Obes (Lond), 38, 170, 10.1038/ijo.2013.82 Keipert, 2015, Genetic disruption of uncoupling protein 1 in mice renders brown adipose tissue a significant source of FGF21 secretion, Mol Metab, 4, 537, 10.1016/j.molmet.2015.04.006 Lee, 2014, Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans, Cell Metab, 19, 302, 10.1016/j.cmet.2013.12.017 Boschi, 2015, Models of lipid droplets growth and fission in adipocyte cells, Exp Cell Res, 336, 253, 10.1016/j.yexcr.2015.06.001 Wu, 2014, Cidea controls lipid droplet fusion and lipid storage in brown and white adipose tissue, Sci China Life Sci, 57, 107, 10.1007/s11427-013-4585-y Yang, 2012, Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB, PLoS One, 7, 10.1371/journal.pone.0033870 Adams, 2013, The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue, Mol Metab, 2, 31, 10.1016/j.molmet.2012.08.007 Li, 2013, SIRT1 and energy metabolism, Acta Biochim Biophys Sin (Shanghai), 45, 51, 10.1093/abbs/gms108 LeMieux, 2015, Eicosapentaenoic acid reduces adipocyte hypertrophy and inflammation in diet-induced obese mice in an adiposity-independent manner, J Nutr, 145, 411, 10.3945/jn.114.202952 de Oliveira, 2012, SIRT2 as a therapeutic target for age-related disorders, Front Pharmacol, 3, 10.3389/fphar.2012.00082 Timmons, 2007, Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages, Proc Natl Acad Sci, 104, 4401, 10.1073/pnas.0610615104 Waldén, 2012, vol. 302, E19 Busiello, 2015, Mitochondrial uncoupling proteins and energy metabolism, Front Physiol, 6, 36, 10.3389/fphys.2015.00036 Fromme, 2011, Uncoupling protein 1 expression and high-fat diets, Am J Physiol Regul Integr Comp Physiol, 300, R1, 10.1152/ajpregu.00411.2010 Rippe, 2003, Effect of long-term high-fat feeding on the expression of pancreatic lipases and adipose tissue uncoupling proteins in mice, Pancreas, 26, e36, 10.1097/00006676-200303000-00024 Busiello, 2015, Mitochondrial uncoupling proteins and energy metabolism, Front Physiol, 6, 10.3389/fphys.2015.00036 Valente, 2015, Molecular pathways linking non-shivering thermogenesis and obesity: focusing on brown adipose tissue development, Biol Rev, 90, 77, 10.1111/brv.12099 Lee, 2013, Effects of eicosapentaenoic acid and docosahexaenoic acid on uncoupling protein 3 gene expression in C(2)C(12) muscle cells, Nutrients, 5, 1660, 10.3390/nu5051660 Symonds, 2013, Brown adipose tissue growth and development, Scientifica, 2013, 10.1155/2013/305763 Yu, 2015, Lipid droplet remodeling and interaction with mitochondria in mouse brown adipose tissue during cold treatment, Biochim Biophys Acta Mol Cell Res, 1853, 918, 10.1016/j.bbamcr.2015.01.020 Park, 2015, Inactivation of EWS reduces PGC-1α protein stability and mitochondrial homeostasis, Proc Natl Acad Sci, 112, 6074, 10.1073/pnas.1504391112 Lee, 2014, Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans, Cell Metab, 19, 302, 10.1016/j.cmet.2013.12.017 Roca-Rivada, 2013, FNDC5/irisin is not only a myokine but also an adipokine, PLoS One, 8, 10.1371/journal.pone.0060563 Sidossis, 2015, Browning of subcutaneous white adipose tissue in humans after severe adrenergic stress, Cell Metab, 22, 219, 10.1016/j.cmet.2015.06.022 Cannon, 2004, Brown adipose tissue: function and physiological significance, Physiol Rev, 84, 277, 10.1152/physrev.00015.2003 Virtue, 2013, Assessment of brown adipose tissue function, Front Physiol, 4, 10.3389/fphys.2013.00128 van Marken Lichtenbelt, 2011, Implications of nonshivering thermogenesis for energy balance regulation in humans, Am J Physiol Regul Integr Comp Physiol, 301, R285, 10.1152/ajpregu.00652.2010 Siriwardhana, 2012, N-3 and n-6 polyunsaturated fatty acids differentially regulate adipose angiotensinogen and other inflammatory adipokines in part via NF-kappaB-dependent mechanisms, J Nutr Biochem, 23, 1661, 10.1016/j.jnutbio.2011.11.009