Journal of Biomedical Materials Research - Part A
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Biocompatibility of poly(ether)urethane‐gold nanocomposites
Journal of Biomedical Materials Research - Part A - Tập 79A Số 4 - Trang 759-770 - 2006
AbstractWe have prepared the nanocomposites of a polyether‐type waterborne
polyurethane (PU) incorporated with different amounts (17.4–174 ppm) of gold
(Au) nanoparticles (∼5 nm). The nanocomposite containing a certain amount (43.5
ppm) of gold was previously demonstrated to possess the optimal thermal and
mechanical properties, as well as much reduced foreign body reactions in
subcutaneous rats. ...
The effects of PRGF on bone regeneration and on titanium implant osseointegration in goats: A histologic and histomorphometric study
Journal of Biomedical Materials Research - Part A - Tập 91A Số 1 - Trang 158-165 - 2009
AbstractThe effect of local application of scaffold‐like preparation rich in
growth factors (PRGF) on bone regeneration in artificial defects and the
potential effect of humidifying titanium dental implants with liquid PRGF on
their osseointegration were investigated. The PRGF formulations were obtained
from venous blood of three goats and applied either as a 3D fibrin scaffold
(scaffold‐like PRGF...
Conformation change of bovine serum albumin induced by bioactive titanium metals and its effects on cell behaviors
Journal of Biomedical Materials Research - Part A - Tập 102 Số 4 - Trang 1053-1062 - 2014
The conformation change of bovine serum albumin (BSA) induced by bioactive
titanium surfaces, including acid‐alkali‐treated titanium (AA‐Ti) and
alkali–heat‐treated titanium (AH‐Ti), was studied, and its effects on the
activity of MC3T3‐E1 cell were evaluated. Pure titanium metal (P‐Ti) was used as
control. The AA‐Ti could adsorb more BSA on its surface than AH‐Ti and P‐Ti. The
α‐helix part of the...
Increased osteoblast adhesion on titanium‐coated hydroxylapatite that forms CaTiO3
Journal of Biomedical Materials Research - Part A - Tập 67A Số 3 - Trang 975-980 - 2003
AbstractCaTiO3 is a strong candidate to form at the interface between
hydroxylapatite (HA) and titanium implants during many coating procedures.
However, few studies have compared the cytocompatibility properties of CaTiO3 to
HA pertinent for bone–cell function. For this reason, the objective of the
present in vitro study was to determine the ability of bone‐forming cells
(osteoblasts) to adhere o...
Osteoblasts behavior on chemically treated commercially pure titanium surfaces
Journal of Biomedical Materials Research - Part A - Tập 102 Số 6 - Trang 1816-1822 - 2014
AbstractSurface modifications of commercially pure titanium (Cp‐Ti), a material
widely used to produce dental implants, can induce specific responses on
osteoblastic cells after implantation. This work aims to investigate the
influence of chemically modified surfaces of Cp‐Ti by acid etching or acid
etching plus alkaline treatment on the gene expression of human osteoblastic
(Hob) cells. Roughness...
Antimicrobial effect of silver‐doped phosphate‐based glasses
Journal of Biomedical Materials Research - Part A - Tập 79A Số 3 - Trang 618-626 - 2006
AbstractIn this study a range of phosphate‐based glasses (PBG) doped with silver
have been investigated for their antimicrobial activities. In disk diffusion
assays, these compositions demonstrated microbistatic effects against a range of
organisms including Staphylococcus aureus, Escherichia coli, Bacillus cereus,
Pseudomonas aeruginosa, methicillin‐resistant Staphylococcus aureus, and Candida
al...
Photochemical cross‐linking of plastically compressed collagen gel produces an optimal scaffold for corneal tissue engineering
Journal of Biomedical Materials Research - Part A - Tập 99A Số 1 - Trang 1-8 - 2011
AbstractThe experiments were designed to use photochemically cross‐linked
plastically compressed collagen (PCPCC) gel to support corneal epithelial cells.
A plastically compressed collagen (PCC) scaffold was photo cross‐linked by UVA
in the presence of riboflavin to form a biomaterial with optimal mechanical
properties. The breaking force, rheology, surgical suture strength,
transparency, ultrastr...
Corneal epithelial adhesion strength to tethered‐protein/peptide modified hydrogel surfaces
Journal of Biomedical Materials Research - Part A - Tập 72A Số 1 - Trang 19-24 - 2005
AbstractIn this study, we investigated the suitability of microjet impingement
for use on hydrogel materials to determine the cellular adhesion strength of
corneal epithelial cells grown on novel hydrogels with extracellular matrix
proteins (laminin and/or fibronectin) or a peptide sequence (fibronectin
adhesion promoting peptide, FAP) tethered to their surface with poly(ethylene
glycol) chains. T...
Crosslinking of collagen with dendrimers
Journal of Biomedical Materials Research - Part A - Tập 75A Số 3 - Trang 510-518 - 2005
AbstractPolypropyleneimine octaamine dendrimers were studied as an alternative
means of generating highly crosslinked collagen. Crosslinking was effected by
using the water‐soluble carbodiimide 1‐ethyl‐3‐(3‐dimethyl aminopropyl)
carbodiimide hydrochloride (EDC). The multifunctional dendrimers were introduced
as novel crosslinkers after the activation of the carboxylic acid groups of
glutamic and a...
Platelet activation through interaction with hemodialysis membranes induces neutrophils to produce reactive oxygen species
Journal of Biomedical Materials Research - Part A - Tập 77A Số 2 - Trang 294-303 - 2006
AbstractThe intradialytic activation of leukocytes is one of the major causes of
hemodialysis‐associated complications. During hemodialysis, the formation of
microaggregates consisting of platelets and neutrophils has been observed to
accompany the production of reactive oxygen species (ROS) by leukocytes. In this
study, we investigated the interaction of platelets and neutrophils with
hemodialysi...
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