Activity‐based costs of blood transfusions in surgical patients at four hospitals Tập 50 Số 4 - Trang 753-765 - 2010
Aryeh Shander, Axel Hofmann, Sherri Ozawa, Oliver M. Theusinger, H. Gombotz, Donat R. Spahn
BACKGROUND: Blood utilization has long been suspected to consume more health care resources than previously reported. Incomplete accounting for blood costs has the potential to misdirect programmatic decision making by health care systems. Determining the cost of supplying patients with blood transfusions requires an in‐depth examination of the complex array of activ...... hiện toàn bộ ABO blood group determines plasma von Willebrand factor levels: a biologic function after all? Tập 46 Số 10 - Trang 1836-1844 - 2006
P. Vincent Jenkins, James S. O’Donnell
For many years, an association between ABO histo‐blood group and risk of thrombosis has been recognized. Blood group non‐O (A, B, and AB) individuals have consistently been found to demonstrate increased incidence of both arterial and venous thrombotic disease, compared to group O individuals. This increased risk is attributable to the fact that ABO blood group influences plasma levels of ...... hiện toàn bộ A Simple Hemagglutination System Requiring Small Amounts of Red Cells and Antibodies Tập 6 Số 1 - Trang 67-73 - 1966
Thomas Wegmann, Oliver Smithies
A method is described which permits dilute red cell suspensions (1/32%) to be used in plastic microtiter plates for detecting hemagglutinins at unusually high dilutions. The use of suitable additives to the hemagglutination mixture enables excellent settling patterns and a high sensitivity to be obtained. Direct agglutination, inhibition, enzyme promoted agglutination, and Coombs tests can...... hiện toàn bộ Improved outcomes and reduced costs associated with a health‐system–wide patient blood management program: a retrospective observational study in four major adult tertiary‐care hospitals Tập 57 Số 6 - Trang 1347-1358 - 2017
Michael F. Leahy, Axel Hofmann, Simon Towler, Kevin M. Trentino, Sally Burrows, Stuart G. Swain, Jeffrey M. Hamdorf, Trudi Gallagher, Audrey Koay, Gary C. Geelhoed, Shannon Farmer
BACKGROUNDPatient blood management (PBM) programs are associated with improved patient outcomes, reduced transfusions and costs. In 2008, the Western Australia Department of Health initiated a comprehensive health‐system–wide PBM program. This study assesses program outcomes.STUDY DESIGN AND METHODS... hiện toàn bộ Detection of three types of hepatitis C virus in blood donors: investigation of type‐specific differences in serologic reactivity and rate of alanine aminotransferase abnormalities Tập 33 Số 1 - Trang 7-13 - 1993
F. McOmish, Shiu‐Wan Chan, B. C. Dow, J. Gillon, W.D. Frame, Robert J. Crawford, P. L. Yap, E. A. C. Follett, Peter Simmonds
The serologic reactivity and epidemiology associated with different hepatitis C virus (HCV) variants were investigated in a cohort of 113 anti‐HCV‐positive donors. In Scotland, HCV type 1 accounted for one‐ half of all infections; 40 percent of subjects were infected with HCV type 3, and the remainder were infected with type 2. Reactivity with the NS‐4‐encoded antigens in the first‐generat...... hiện toàn bộ An update on red blood cell storage lesions, as gleaned through biochemistry and omics technologies Tập 55 Số 1 - Trang 205-219 - 2015
Angelo D’Alessandro, Anastasios G. Kriebardis, Sara Rinalducci, Marianna H. Antonelou, Kirk C. Hansen, Issidora S. Papassideri, Lello Zolla
Red blood cell (RBC) aging in the blood bank is characterized by the accumulation of a significant number of biochemical and morphologic alterations. Recent mass spectrometry and electron microscopy studies have provided novel insights into the molecular changes underpinning the accumulation of storage lesions to... hiện toàn bộ