Transfusion

Công bố khoa học tiêu biểu

* Dữ liệu chỉ mang tính chất tham khảo

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Orthopedic Surgery Transfusion Hemoglobin European Overview (OSTHEO) study: blood management in elective knee and hip arthroplasty in Europe*
Transfusion - Tập 43 Số 4 - Trang 459-469 - 2003
Nadia Rosencher, H. E. M. Kerkkamp, George A. Macheras, L. Munuera, G Menichella, David M. Barton, Saskia Cremers, Ivo Abraham, For The OSTHEO Investigation
BACKGROUND: The purpose of this study was to assess current practices in blood management in elective orthopedic surgery in Europe. STUDY DESIGN AND METHODS: For this 225‐center prospective survey, data were collected on 3996 patients. Actual perioperative blood loss was compared to preoperative estimates. Differences in Hb le...... hiện toàn bộ
Improved outcomes and reduced costs associated with a health‐system–wide patient blood management program: a retrospective observational study in four major adult tertiary‐care hospitals
Transfusion - Tập 57 Số 6 - Trang 1347-1358 - 2017
Michael F. Leahy, Axel Hofmann, Simon Towler, Kevin M. Trentino, Sally Burrows, Stuart G. Swain, Jeffrey M. Hamdorf, Trudi Gallagher, Audrey Koay, Gary C. Geelhoed, Shannon Farmer
BACKGROUNDPatient blood management (PBM) programs are associated with improved patient outcomes, reduced transfusions and costs. In 2008, the Western Australia Department of Health initiated a comprehensive health‐system–wide PBM program. This study assesses program outcomes.STUDY DESIGN AND METHODS... hiện toàn bộ
Induction of lymphokine‐activated killer and natural killer cell activities from cryopreserved lymphocytes
Transfusion - Tập 28 Số 6 - Trang 531-535 - 1988
Hiroshi Kawai, Atsushi Komiyama, Miyuki Katoh, Akihiko Yabuhara, Yukiaki Miyagawa, T Akabane
Lymphokine‐activated killer (LAK) and natural killer (NK) cells were studied for their capacity to retain cytotoxicity after cryopreservation. LAK cells were generated by a 4‐day culture of lymphocytes with recombinant interleukin‐2 (rIL‐2). Cytotoxicity was measured by 51Cr‐release assay at effector:target ratios of 10:1 to 80:1. Cryopreserved LAK cells retained 58.8 ...... hiện toàn bộ
An update on red blood cell storage lesions, as gleaned through biochemistry and omics technologies
Transfusion - Tập 55 Số 1 - Trang 205-219 - 2015
Angelo D’Alessandro, Anastasios G. Kriebardis, Sara Rinalducci, Marianna H. Antonelou, Kirk C. Hansen, Issidora S. Papassideri, Lello Zolla
Red blood cell (RBC) aging in the blood bank is characterized by the accumulation of a significant number of biochemical and morphologic alterations. Recent mass spectrometry and electron microscopy studies have provided novel insights into the molecular changes underpinning the accumulation of storage lesions to... hiện toàn bộ
Storage lesion: role of red blood cell breakdown
Transfusion - Tập 51 Số 4 - Trang 844-851 - 2011
Daniel B. Kim‐Shapiro, Janet Lee, Mark T. Gladwin
As stored blood ages intraerythrocytic energy sources are depleted resulting in reduced structural integrity of the membrane. Thus, stored red blood cells (RBCs) become less deformable and more fragile as they age. This fragility leads to release of cell‐free hemoglobin (Hb) and formation of microparticles, submicron Hb‐containing vesicles. Upon transfusion, it is likely that additional he...... hiện toàn bộ
Neutrophils release extracellular DNA traps during storage of red blood cell units
Transfusion - Tập 53 Số 12 - Trang 3210-3216 - 2013
Tobias A. Fuchs, Javier J. Alvarez, Kimberly Martinod, A. Bhandari, Richard M. Kaufman, Denisa D. Wagner
BackgroundBlood transfusion is associated with an increased risk of organ damage, infection, and alloimmunity. Neutrophil extracellular traps (NETs) are extracellular chromatin fibers decorated with neutrophil granular proteins that have been linked to cytotoxicity, thrombosis, and autoimmunity...... hiện toàn bộ
Transfusion of 35‐day stored red blood cells does not result in increase of plasma non‐transferrin bound iron in human endotoxemia
Transfusion - Tập 57 Số 1 - Trang 53-59 - 2017
Anna L. Peters, Renoja K. Kunanayagam, Robin van Bruggen, Dirk de Korte, Nicole P. Juffermans, Alexander P. J. Vlaar
BACKGROUNDTransfusion of a single unit of stored red blood cells (RBCs) has been hypothesized to induce supra‐physiological levels of non‐transferrin bound iron (NTBI), which may enhance inflammation and act as a nutrient for bacteria. We investigated the relation between RBC storage time and iron levels in a clinically relevant “two‐hit” human transfusio...... hiện toàn bộ
White cell apoptosis in packed red cells
Transfusion - Tập 38 Số 11-12 - Trang 1082-1089 - 1998
Flavia Frabetti, D. Musiani, Marina Marini, Claudia Fanelli, Simona Coppola, Lina Ghibelli, Pier Luigi Tazzari, Andrea Bontadini, Cristina Tassi, Roberto Conte
BACKGROUND: After the removal of the buffy coat, packed red cell (RBC) transfusion units still contain white cells that may undergo apoptosis as a result of storage conditions (1‐6 degrees C). The aim of the present study was the evaluation of this phenomenon in view of the possible influence it may have on febrile nonhemolytic transfusion reactions. STUDY DESIGN AND METHODS: Three indepen...... hiện toàn bộ
A quality monitoring program for red blood cell components: in vitro quality indicators before and after implementation of semiautomated processing
Transfusion - Tập 54 Số 10 - Trang 2534-2543 - 2014
Jason P. Acker, Arild E. Hansen, Jayme D.R. Kurach, Tracey R. Turner, Ioana M Croteau, Craig Jenkins
BackgroundCanadian Blood Services has been conducting quality monitoring of red blood cell (RBC) components s...... hiện toàn bộ
The National Heart, Lung, and Blood Institute Recipient Epidemiology and Donor Evaluation Study (REDS‐III): a research program striving to improve blood donor and transfusion recipient outcomes
Transfusion - Tập 54 Số 3pt2 - Trang 942-955 - 2014
Steven Kleinman, Michael P. Busch, Edward L. Murphy, Hua Shan, Paul M. Ness, Simone A. Glynn
BackgroundThe Recipient Epidemiology and D...... hiện toàn bộ
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