AbstractIn the field of cardio-oncology, it is well recognised that despite the
benefits of chemotherapy in treating and possibly curing cancer, it can cause
catastrophic damage to bystander tissues resulting in a range of potentially of
life-threatening cardiovascular toxicities, and leading to a number of damaging
side effects including heart failure and myocardial infarction. Cardiotoxicity
is ... hiện toàn bộ
Richard W. Troughton, Jay Ritzema, Neal Eigler, Iain Melton, Henry Krum, Philip B. Adamson, Saibal Kar, Prediman K. Shah, James S. Whiting, J. Thomas Heywood, Spencer Rosero, Jagmeet P. Singh, Leslie A. Saxon, Ray V. Matthews, Ian Crozier, William T. Abraham
The potency of specific transcription factors as cell fate determinants was
first demonstrated by the discovery of MyoD, a master gene for skeletal muscle
transdifferentiation. More recently, the induction of pluripotency in somatic
cells using a combination of stem cell-specific transcription factors has been
reported. That elegant study altered the approach to regenerative medicine and
inspired ... hiện toàn bộ