Small Molecule Screening in Zebrafish
Tóm tắt
Từ khóa
Tài liệu tham khảo
Neuhauss, S. C., Solnica-Krezel, L., Schier, A. F., Zwartkruis, F., Stemple, D. L., et al. (1996). Mutations affecting craniofacial development in zebrafish. Development, 123, 357–367.
Stainier, D. Y. R., Fouquet, B., Chen, J. N., Warren, K. S., Weinstein, B. M., et al. (1996). Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development, 123, 285–292.
Burns, C. G., Milan, D. J., Grande, E. J., Rottbauer, W., MacRae, C. A., et al. (2005). High-throughput assay for small molecules that modulate zebrafish embryonic heart rate. Nature Chemical Biology, 1, 263–264.
Kokel, D., Bryan, J., Laggner, C., White, R., Cheung, C. Y. J., et al. (2010). Rapid behavior-based identification of neuroactive small molecules in the zebrafish. Nature Chemical Biology, 6, 231–237.
Xu, X., Meiler, S. E., Zhong, T. P., Mohideen, M., Crossley, D. A., et al. (2002). Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin. Nature Genetics, 30, 205.
Stoletov, K., Fang, L., Choi, S. H., Hartvigsen, K., Hansen, L. F., et al. (2009). Vascular lipid accumulation, lipoprotein oxidation, and macrophage lipid uptake in hypercholesterolemic zebrafish. Circulation Research, 104, 952–960.
Kopp, R., Schwerte, T., & Pelster, B. (2005). Cardiac performance in the zebrafish breakdance mutant. The Journal of Experimental Biology, 208, 2123–2134.
Peterson, R. T., Shaw, S. Y., Peterson, T. A., Milan, D. J., Zhong, T. P., et al. (2004). Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation. Nature Biotechnology, 22, 595–599.
Heuser, A., Plovie, E. R., Ellinor, P. T., Grossmann, K. S., Shin, J. T., et al. (2006) Mutant desmocollin-2 causes arrhythmogenic right ventricular cardiomyopathy. 79: 1081–1088.
Peterson, R. T., Link, B. A., Dowling, J. E., & Schreiber, S. L. (2000). Small molecule developmental screens reveal the logic and timing of vertebrate development. Proceedings of the National Academy of Sciences of the United States of America, 97, 12965–12969.
Kitambi, S. S., McCulloch, K. J., Peterson, R. T., & Malicki, J. J. (2009). Small molecule screen for compounds that affect vascular development in the zebrafish retina. Mechanisms of Development, 126, 464–477.
Alvarez, Y., Astudillo, O., Jensen, L., Reynolds, A. L., Waghorne, N., et al. (2009). Selective inhibition of retinal angiogenesis by targeting PI3 kinase. PLoS ONE, 4, e7867.
North, T. E., Goessling, W., Walkley, C. R., Lengerke, C., Kopani, K. R., et al. (2007). Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature, 447, 1007–1011.
Giacomotto, J., & Segalat, L. (2010). High-throughput screening and small animal models, where are we? British Journal of Pharmacology, 160, 204–216.
Reim, I., & Frasch, M. (2010). Genetic and genomic dissection of cardiogenesis in the Drosophila model. Pediatric Cardiology, 31, 325–334.
Armstrong, E. J., & Bischoff, J. (2004). Heart valve development: endothelial cell signaling and differentiation. Circulation Research, 95, 459–470.
Milan, D. J., Peterson, T. A., Ruskin, J. N., Peterson, R. T., & MacRae, C. A. (2003). Drugs that induce repolarization abnormalities cause bradycardia in zebrafish. Circulation, 107, 1355–1358.
Murphey, R. D., Stern, H. M., Straub, C. T., & Zon, L. I. (2006). A chemical genetic screen for cell cycle inhibitors in zebrafish embryos. Chemical Biology & Drug Design, 68, 213–219.
Torregroza, I., Evans, T., & Das, B. C. (2009). A forward chemical screen using zebrafish embryos with novel 2-substituted 2H-chromene derivatives. Chemical Biology & Drug Design, 73, 339–345.
Yu, P. B., Hong, C. C., Sachidanandan, C., Babitt, J. L., Deng, D. Y., et al. (2008). Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nature Chemical Biology, 4, 33–41.
Cuny, G. D., Yu, P. B., Laha, J. K., Xing, X., Liu, J. F., et al. (2008). Structure–activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors. Bioorganic & Medicinal Chemistry Letters, 18, 4388–4392.
Yu, P. B., Deng, D. Y., Lai, C. S., Hong, C. C., Cuny, G. D., et al. (2008). BMP type I receptor inhibition reduces heterotopic ossification. Nature Medicine, 14, 1363–1369.
Molina, G. A., Watkins, S. C., & Tsang, M. (2007). Generation of FGF reporter transgenic zebrafish and their utility in chemical screens. BMC Developmental Biology, 7, 62–14.
Molina, G., Vogt, A., Bakan, A., Dai, W., de Oliveira, P. Q., et al. (2009). Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages. Nature Chemical Biology, 5, 680–687.
Ren, B., Deng, Y., Mukhopadhyay, A., Lanahan, A. A., Zhuang, Z. W., et al. (2010). ERK1/2-Akt1 crosstalk regulates arteriogenesis in mice and zebrafish. The Journal of Clinical Investigation, 120, 1217–1228.
Owens, K. N., Santos, F., Roberts, B., Linbo, T., Coffin, A. B., et al. (2008). Identification of genetic and chemical modulators of zebrafish mechanosensory hair cell death. PLoS Genetics, 4, 1–14.
Cao, Y., Semanchik, N., Lee, S. H., Somlo, S., Barbano, P. E., et al. (2009). Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models. Proceedings of the National Academy of Sciences, 106, 21819–21824.
Yeh, J. R. J., Munson, K. M., Elagib, K. E., Goldfarb, A. N., Sweetser, D. A., et al. (2009). Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation. Nature Chemical Biology, 5, 236–243.
Mathew, L. K., Sengupta, S., Kawakami, A., Andreasen, E. A., Lohr, C. V., et al. (2007). Unraveling tissue regeneration pathways using chemical genetics. The Journal of Biological Chemistry, 282, 35202–35210.
Sachidanandan, C., Yeh, J. R. J., Peterson, Q. P., & Peterson, R. T. (2008). Identification of a novel retinoid by small molecule screening with zebrafish embryos. PLoS ONE, 3, e1947.
Peterson, R. T., Mably, J. D., Chen, J.-N., & Fishman, M. C. (2001). Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul. Current Biology, 11, 1481–1491.
Keiser, M., Roth, B., Armbruster, B., Ernsberger, P., Irwin, J., et al. (2007). Relating protein pharmacology by ligand chemistry. Nature Biotechnology, 25, 197–206.
Teng, X., Keys, H., Yuan, J., Degterev, A., & Cuny, G. D. (2008). Structure-activity relationship and liver microsome stability studies of pyrrole necroptosis inhibitors. Bioorganic & Medicinal Chemistry Letters, 18, 3219–3223.
Hao, J., Ho, J. N., Lewis, J. A., Karim, K. A., Daniels, R. N., et al. (2009). In vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitors. ACS Chemical Biology, 5, 245–253.
Jung, D.-W., Williams, D., Khersonsky, S. M., Kang, T.-W., Heidary, N., et al. (2005). Identification of the F1F0 mitochondrial ATPase as a target for modulating skin pigmentation by screening a tagged triazine library in zebrafish. Molecular Biosystems, 1, 85–92.
Ni-Komatsu, L., & Orlow, S. J. (2007). Identification of novel pigmentation modulators by chemical genetic screening. The Journal of Investigative Dermatology, 127, 1585–1592.
Rihel, J., Prober, D. A., Arvanites, A., Lam, K., Zimmerman, S., et al. (2010). Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation. Science, 327, 348–351.