Journal of Cardiovascular Translational Research

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iPS Cell Modeling of Cardiometabolic Diseases
Journal of Cardiovascular Translational Research - Tập 6 - Trang 46-53 - 2012
Kenta Nakamura, Ken-ichi Hirano, Sean M. Wu
Cardiometabolic diseases encompass simple monogenic enzyme deficiencies with well-established pathogenesis and clinical outcomes to complex polygenic diseases such as the cardiometabolic syndrome. The limited availability of relevant human cell types such as cardiomyocytes has hampered our ability to adequately model and study pathways or drugs relevant to these diseases in the heart. The recent d...... hiện toàn bộ
Efficacy and Dosage Pattern of Sacubitril/Valsartan in Chinese Heart Failure with Reduced Ejection Fraction Patients
Journal of Cardiovascular Translational Research - Tập 15 - Trang 1192-1202 - 2022
Iokfai Cheang, Shi Shi, Xinyi Lu, Shengen Liao, Xu Zhu, Xi Su, Qi Lu, Jing Yuan, Dachun Xu, Min Zhang, Cuilian Dai, Jingfeng Wang, Fang Yuan, Yan Zhao, Jingmin Zhou, Xinli Li
This study aims to investigate the dosage pattern, efficacy, and safety of sacubitril/valsartan (Sac/Val) in Chinese heart failure with reduced ejection fraction (HFrEF) patients regarding real-world settings. Patients from 27 centers with a confirmed diagnosis of HFrEF and initiated Sac/Val treatment were enrolled. The primary objective was to evaluate the dosage pattern and change of heart failu...... hiện toàn bộ
Empagliflozin for Patients with Heart Failure and Type 2 Diabetes Mellitus: Clinical Evidence in Comparison with Other Sodium-Glucose Co-transporter-2 Inhibitors and Potential Mechanism
Journal of Cardiovascular Translational Research - Tập 16 - Trang 327-340 - 2022
Bo Liang, Rui Li, Peng Zhang, Ning Gu
Heart failure remains a leading cause of morbidity and mortality globally and has been recognized as a common complication of diabetes, especially type 2 diabetes mellitus. Heart failure occurs in diabetic patients even in the absence of hypertension, coronary heart disease, or valvular heart disease, and is, therefore, a major cardiovascular complication in this vulnerable population. Given the c...... hiện toàn bộ
Clinical Practice and Research in Cardio-Oncology: Finding the “Rosetta Stone” for Establishing Program Excellence in Cardio-oncology
Journal of Cardiovascular Translational Research - Tập 13 - Trang 495-505 - 2020
Srinath Adusumalli, Jose Alvarez-Cardona, Sameed M. Khatana, Joshua D. Mitchell, Anne H. Blaes, Stephen J. Casselli, Rupal O’Quinn, Daniel J. Lenihan
The burgeoning field of cardio-oncology (C-O) is now necessary for the delivery of excellent care for patients with cancer. Many factors have contributed to this increasing population of cancer survivors or those being treated with novel and targeted cancer therapies. There is a tremendous need to provide outstanding cardiovascular (CV) care for these patients; however, current medical literature ...... hiện toàn bộ
Diagnostic and Prognostic Value of Coronary Computed Tomography Angiography in Patients with Severe Calcification
Journal of Cardiovascular Translational Research - Tập 14 - Trang 131-139 - 2020
Belén Díaz-Antón, Jorge Solís, Roberto Díaz Morales, Beatriz López-Melgar, Patricia Barrio, Andrea Moreno, Leire Unzué, Antonio Alvarez-Vieitez, Juan Medina, Eulogio García, Francisco Javier Parra Jiménez, Leticia Fernández-Friera
Our aim was to analyze its diagnostic and prognostic value in patients with high coronary calcium score (CCS). A total of 113 patients with CCS > 400 were included. Significant coronary artery disease (CAD) was defined as stenosis ≥ 50%. Invasive coronary angiography and major cardiovascular events were recorded. The CCS and heart rate during the acquisition were significantly lower in the diagnos...... hiện toàn bộ
Myocarditis in the Athlete: Arrhythmogenic Substrates, Clinical Manifestations, Management, and Eligibility Decisions
Journal of Cardiovascular Translational Research - Tập 13 Số 3 - Trang 284-295 - 2020
Vio, Riccardo, Zorzi, Alessandro, Corrado, Domenico
Myocarditis is as an important cause of sudden cardiac death (SCD) among athletes. The incidence of SCD ascribed to myocarditis did not change after the introduction of pre-participation screening in Italy, due to the transient nature of the disease and problems in the differential diagnosis with the athlete’s heart. The arrhythmic burden and the underlying mechanisms differ between the acute and ...... hiện toàn bộ
Predictive Models for Pulmonary Artery Size in Fontan Patients
Journal of Cardiovascular Translational Research - Tập 14 - Trang 782-789 - 2020
Akash Gupta, Chris Gillett, Patrick Gerard, Michael M. H. Cheung, Jonathan P. Mynard, Ethan Kung
We developed models of pulmonary artery (PA) size in Fontan patients as a function of age and body surface area (BSA) using linear regression and breakpoint analyses based on data from 43 Fontan patients divided into two groups: the extracardiac conduit (ECC) group (n = 24) and the non-ECC group (n = 19). Model predictions were compared against those of a non-Fontan control group (n = 18) and publ...... hiện toàn bộ
Metabolic Reprogramming in Cardiovascular Diseases
Journal of Cardiovascular Translational Research - - Trang 1-3 - 2024
Juan Gao, Yujiao Zhu, Yihua Bei
Non-invasive Thoracic Impedance Changes in COVID-19 Pulmonary Infection
Journal of Cardiovascular Translational Research - - 2021
Sunil Kapur, Michael O. Sweeney, William H. Sauer, Calum A. MacRae
Intermittent Occlusion of the Superior Vena Cava Reduces Cardiac Filling Pressures in Preclinical Models of Heart Failure
Journal of Cardiovascular Translational Research - - 2020
Navin K. Kapur, Lara Reyelt, Paige Crowley, Lauren Richey, John McCarthy, Shiva Annamalai, Susan Newman, Lena Jorde, Sina Forotuanjazi, Allen Razavi, Tim Lenihan, Daniel Burkhoff, Richard H. Karas
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