Journal of Biomedical Materials Research - Part B Applied Biomaterials

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Controlled release of complexed DNA from polycaprolactone film: Comparison of lipoplex and polyplex release
Journal of Biomedical Materials Research - Part B Applied Biomaterials - Tập 89B Số 2 - Trang 439-447 - 2009
Yamini Ramgopal, Debasish Mondal, Subbu S. Venkatraman, W.T. Godbey, Gan Yik Yuen
AbstractThis report investigates the comparative in vitro controlled release and transfection efficiencies of pDNA‐lipofectamine complex (lipoplex) and pDNA‐poly(ethylene imine) complex (polyplex), from a biodegradable polycaprolactone (PCL) film. The effect of molecular weight of gelatin used as a porogen on in vitro release and transfection efficiency was also studied. A sustained release profil... hiện toàn bộ
Effectiveness of autologous preparation rich in growth factors for the treatment of chronic cutaneous ulcers
Journal of Biomedical Materials Research - Part B Applied Biomaterials - Tập 84B Số 2 - Trang 415-421 - 2008
Eduardo Anitua, José Javier Aguirre, Jaime Algorta, Eduardo Ayerdi, Ana I. Cabezas, Gorka Orive, Isabel Andı́a
AbstractAutologous Preparation Rich in Growth Factors (PRGF), a small volume of plasma enriched in platelets, is a novel therapeutic strategy for the acceleration of the wound healing of a wide range of tissues because of the continuous release of multiple growth factors, including PDGF‐AB, TGF‐β1, IGF‐I, HGF, VEGF‐A, and EGF. In this article, we have characterized the PRGF preparation and designe... hiện toàn bộ
Osteoinduction of porous titanium: A comparative study between acid‐alkali and chemical‐thermal treatments
Journal of Biomedical Materials Research - Part B Applied Biomaterials - Tập 95B Số 2 - Trang 387-396 - 2010
Chaoyong Zhao, Xiangdong Zhu, Kailu Liang, Jietao Ding, Zhou Xiang, Hongsong Fan, Xingdong Zhang
AbstractIn this study, a slurry foaming method was developed to fabricate porous titanium, and two different surface treatments were applied to investigate their effects on the osteoinduction of the implants. Three types of implants, that was porous titanium with no treatment, with chemical‐thermal treatment (CTPT), and with acid‐alkali treatment (AAPT), were implanted in the dorsal muscles of adu... hiện toàn bộ
Characterization of hydroxyapatite‐perovskite (CaTiO3) composites: Phase evaluation and cellular response
Journal of Biomedical Materials Research - Part B Applied Biomaterials - Tập 95B Số 2 - Trang 320-329 - 2010
Ashutosh Kumar Dubey, Garima Tripathi, Bikramjit Basu
AbstractIn this study, an attempt was made to develop an understanding of the densification behavior, phase stability, and biocompatibility property of HA‐CaTiO3 biocomposite. The composites with varying CaTiO3 (40–80 wt %) content were sintered at temperatures ranging from 1200°C to 1500°C for 3–5 hr to establish optimum processing parameters. The phase analysis using spectral techniques indicate... hiện toàn bộ
Improved hemodialysis with hemocompatible polyethersulfone hollow fiber membranes: In vitro performance
Journal of Biomedical Materials Research - Part B Applied Biomaterials - Tập 106 Số 3 - Trang 1286-1298 - 2018
Surendra Kumar Verma, Akshay Modi, Atul Kumar Singh, Rohit Teotia, Jayesh Bellare
AbstractWe show that addition of nanozeolite (NZ) and vitamin E D‐α‐Tocopherol polyethylene glycol succinate (TPGS or T) considerably improves the performance of polyethersulfone (PES or P) hollow fiber membrane (HFM) for hemodialysis. Nanocomposite HFMs were manufactured using PES as a polymer, TPGS as an additive and NZ as a filler to give a composite membrane called PT‐NZ. HFMs were spun by dry... hiện toàn bộ
Polydopamine/cysteine surface modified hemocompatible poly(vinylidene fluoride) hollow fiber membranes for hemodialysis
Journal of Biomedical Materials Research - Part B Applied Biomaterials - Tập 106 Số 8 - Trang 2869-2877 - 2018
Zihan An, Fengying Dai, Chenjie Wei, Yiping Zhao, Li Chen
AbstractMembrane surface design is significant for the development and application of synthetic polymer hemodialysis membranes. In this study, the influence of zwitterionic cysteine on poly(vinylidene fluoride) (PVDF) hollow fiber membrane was investigated. The polydopamine layer was formed through dopamine self‐polymerization on PVDF membrane surface, and then cysteine was covalent grafted onto t... hiện toàn bộ
Comparison of in vitro with in vivo characteristics of wear particles from metal–metal hip implants
Journal of Biomedical Materials Research - Part B Applied Biomaterials - Tập 70B Số 2 - Trang 167-178 - 2004
Isabelle Catelas, John B. Medley, Pat Campbell, Olga L. Huk, J Bobyn
AbstractThe purpose of the present study was to compare wear particles isolated from metal–metal (MM) hip implants worn in an orbital bearing simulator with particles from similar MM total hip replacement (THR) implants worn in vivo. Comparison of these particles is important because it will help to assess the overall suitability of this type of hip simulator for reproducing in vivo wear and for p... hiện toàn bộ
Metal‐on‐metal bearing wear with different swing phase loads
Journal of Biomedical Materials Research - Part B Applied Biomaterials - Tập 70B Số 2 - Trang 233-239 - 2004
Sophie Williams, Todd Stewart, Eileen Ingham, M H Stone, John Fisher
AbstractThere is currently much discussion about the most clinically relevant testing methods for evaluating total hip replacements. This study examined the effect of different swing phase loads, including microseparation, on the wear, friction, and wear particles of metal‐on‐metal (MOM) hip replacements. MOM hip replacements were tested for 5 million cycles with the use of a hip simulator; prosth... hiện toàn bộ
Long‐term wear of ceramic matrix composite materials for hip prostheses under severe swing phase microseparation
Journal of Biomedical Materials Research - Part B Applied Biomaterials - Tập 66B Số 2 - Trang 567-573 - 2003
Todd Stewart, Joanne L. Tipper, Gerard Insley, Robert Streicher, Eileen Ingham, John Fisher
AbstractThe purpose of this study was to evaluate the long‐term wear performance of alumina matrix composite (AMC) heads against alumina matrix composite inserts and alumina matrix composite heads against alumina (Al) inserts with the use of a hip‐joint simulator incorporating severe swing phase joint microseparation. The wear of AMC on Al produced an average wear rate of 0.61 mm3/million cycles o... hiện toàn bộ
Stripe wear rates in alumina THR—Comparison of microseparation simulator study with retrieved implants
Journal of Biomedical Materials Research - Part B Applied Biomaterials - Tập 69B Số 2 - Trang 149-157 - 2004
M. Manaka, Ian C. Clarke, Kengo Yamamoto, Takaaki Shishido, Allen Gustafson, Atsuhiro Imakiire
AbstractAlumina‐on‐alumina hip implants with microseparation were run in a hip simulator for comparison of the nonseparation simulator mode and retrievals. The 28‐, 32‐, and 36‐mm Biolox‐forte implants were run to 5 million cycles with the use of 50% newborn calf serum. Howmedica Osteonics Trident cups with titanium backing were used in all sets. In standard (STD) and microseparation (MSX) mode, t... hiện toàn bộ
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