Effectiveness of autologous preparation rich in growth factors for the treatment of chronic cutaneous ulcers
Tóm tắt
Autologous Preparation Rich in Growth Factors (PRGF), a small volume of plasma enriched in platelets, is a novel therapeutic strategy for the acceleration of the wound healing of a wide range of tissues because of the continuous release of multiple growth factors, including PDGF‐AB, TGF‐β1, IGF‐I, HGF, VEGF‐A, and EGF. In this article, we have characterized the PRGF preparation and designed a randomized open‐label controlled pilot trial to evaluate the effectiveness of PRGF in the treatment of chronic cutaneous ulcers. Results showed that at 8 weeks, the mean percentage of surface healed in the PRGF group was 72.94% ± 22.25% whereas it was 21.48% ± 33.56% in the control group (
Từ khóa
Tài liệu tham khảo
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