Journal of Biochemical and Molecular Toxicology
SCIE-ISI SCOPUS (SonsInc.)
1095-6670
1099-0461
Mỹ
Cơ quản chủ quản: John Wiley & Sons Inc. , WILEY
Lĩnh vực:
BiochemistryMedicine (miscellaneous)Molecular BiologyMolecular MedicineToxicologyHealth, Toxicology and Mutagenesis
Các bài báo tiêu biểu
Diabetes, oxidative stress, and antioxidants: A reviewAbstract Increasing evidence in both experimental and clinical studies suggests that oxidative stress plays a major role in the pathogenesis of both types of diabetes mellitus. Free radicals are formed disproportionately in diabetes by glucose oxidation, nonenzymatic glycation of proteins, and the subsequent oxidative degradation of glycated proteins. Abnormally hig... ... hiện toàn bộ
Tập 17 Số 1 - Trang 24-38 - 2003
Protective effect of caffeic acid phenethyl ester (CAPE) on lipid peroxidation and antioxidant enzymes in diabetic rat liverAbstract The aim of this study was to examine the effect of caffeic acid phenethyl ester (CAPE) on lipid peroxidation (LPO) and the activities of antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH‐Px) in the liver of streptozotocin (STZ)‐induced diabetic rats. Twenty‐seven rats were randomly divided into three gro... ... hiện toàn bộ
Tập 18 Số 4 - Trang 234-238 - 2004
The antidiabetic and anticholinergic effects of chrysin on cyclophosphamide‐induced multiple organ toxicity in rats: Pharmacological evaluation of some metabolic enzyme activitiesAbstract Chrysin (CH) or 5,7‐dihydroxyflavone is a flavonoid present in various plants, bee propolis, and honey. Cyclophosphamide (CYP) is a chemotherapeutic drug, which is extensively used in the treatment of multiple human malignancies. In our study, we aimed to investigate the effects of CYP and CH on some metabolic enzymes including carbonic anhydrase, aldose re... ... hiện toàn bộ
Tập 33 Số 6 - 2019
Effects of diallyl sulfide and zinc on testicular steroidogenesis in cadmium‐treated male ratsAbstract Cadmium (Cd) is one of the environmental pollutants that affect various tissues and organs including testis. Harmful effect of cadmium on testis is known to be germ cell degeneration and impairment of testicular steroidogenesis. In the present study, the effect of diallyl sulfide (DAS), a sulfur‐containing volatile compound present in garlic, and zinc (Zn) ... ... hiện toàn bộ
Tập 22 Số 5 - Trang 345-353 - 2008
Protective effects of thymol on altered plasma lipid peroxidation and nonenzymic antioxidants in isoproterenol‐induced myocardial infarcted ratsAbstract This study evaluates the protective effects of thymol on altered plasma lipid peroxidation products and nonenzymic antioxidants in isoproterenol (ISO)‐induced myocardial infarcted rats. Male albino Wistar rats were pre and cotreated with thymol (7.5 mg/kg body weight) daily for 7 days. ISO (100 mg/kg body weight) was subcutaneously injected into rats on 6th... ... hiện toàn bộ
Tập 26 Số 9 - Trang 368-373 - 2012
RETRACTED: Preventive effect of naringin on cardiac mitochondrial enzymes during isoproterenol‐induced myocardial infarction in rats: A transmission electron microscopic studyAbstract Dietary flavonoids intake has been reported inversely related to the incidence of cardiovascular diseases (CVD). The present study is undertaken to evaluate the preventive role of naringin on mitochondrial enzymes in isoproterenol (ISO)‐induced myocardial infarction in male albino Wistar rats. Rats subcutaneously injected with ISO (85 mg/kg) at an interval ... ... hiện toàn bộ
Tập 21 Số 6 - Trang 354-361 - 2007
Cisplatin‐Induced Testicular Toxicity in Rats: The Protective Effect of Arjunolic AcidABSTRACT In the present study, the effect of arjunolic acid on testicular damage induced by intraperitoneal injection of rats with 7 mg/kg cisplatin was studied. Cisplatin induced a significant reduction in testicular weights, plasma testosterone, and testicular reduced glutathione levels in addition to a significant elevation of testicular malondialdehyde levels an... ... hiện toàn bộ
Tập 28 Số 11 - Trang 515-521 - 2014
Dietary Antioxidant, Quercetin, Protects Sertoli‐Germ Cell Coculture from Atrazine‐Induced Oxidative DamageABSTRACT Quercetin (QT ), a dietary‐derived flavonoid, is ubiquitous in fruits and vegetables and plays an important role in human health by virtue of its antioxidant function. The present study was designed to examine the effects of QT on oxida... ... hiện toàn bộ
Tập 26 Số 11 - Trang 477-485 - 2012
The effects of mesenchymal stem cell mitochondrial transplantation on doxorubicin‐mediated nephrotoxicity in ratsAbstract The effect of dysfunctional mitochondria in several cell pathologies has been reported in renal diseases, including diabetic nephropathy and acute kidney injury. Previous studies have reported that mitochondrial transplantation provided surprising results in myocardial and liver ischemia, as well as in Parkinson's disease. We aimed to investigate the benefi... ... hiện toàn bộ
Tập 35 Số 1 - 2021
A Comparison between the Nephrotoxic Profile of Gentamicin and Gentamicin Nanoparticles in MiceABSTRACT Aminoglycoside antibiotics are widely used against Gram‐negative infections. On the other hand, nephrotoxicity is a deleterious side effect associated with aminoglycoside therapy. Gentamicin is the most nephrotoxic aminoglycoside. Because of serious health complications ensue the nephrotoxicity induced by aminoglycosides, finding new therapeutic strategies ... ... hiện toàn bộ
Tập 29 Số 2 - Trang 57-62 - 2015