Journal of Biochemical and Molecular Toxicology
SCIE-ISI SCOPUS (1998-2025)
1095-6670
1099-0461
Mỹ
Cơ quản chủ quản: John Wiley & Sons Inc. , WILEY
Lĩnh vực:
BiochemistryMedicine (miscellaneous)Molecular BiologyMolecular MedicineToxicologyHealth, Toxicology and Mutagenesis
Phân tích ảnh hưởng
Các bài báo tiêu biểu
Diabetes, oxidative stress, and antioxidants: A review
Tập 17 Số 1 - Trang 24-38 - 2003
AbstractIncreasing evidence in both experimental and clinical studies suggests
that oxidative stress plays a major role in the pathogenesis of both types of
diabetes mellitus. Free radicals are formed disproportionately in diabetes by
glucose oxidation, nonenzymatic glycation of proteins, and the subsequent
oxidative degradation of glycated proteins. Abnormally high levels of free
radicals and the...
Protective effect of caffeic acid phenethyl ester (CAPE) on lipid peroxidation and antioxidant enzymes in diabetic rat liver
Tập 18 Số 4 - Trang 234-238 - 2004
AbstractThe aim of this study was to examine the effect of caffeic acid
phenethyl ester (CAPE) on lipid peroxidation (LPO) and the activities of
antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), and
glutathione peroxidase (GSH‐Px) in the liver of streptozotocin (STZ)‐induced
diabetic rats. Twenty‐seven rats were randomly divided into three groups: group
I, control non‐diabeti...
The antidiabetic and anticholinergic effects of chrysin on cyclophosphamide‐induced multiple organ toxicity in rats: Pharmacological evaluation of some metabolic enzyme activities
Tập 33 Số 6 - 2019
AbstractChrysin (CH) or 5,7‐dihydroxyflavone is a flavonoid present in various
plants, bee propolis, and honey. Cyclophosphamide (CYP) is a chemotherapeutic
drug, which is extensively used in the treatment of multiple human malignancies.
In our study, we aimed to investigate the effects of CYP and CH on some
metabolic enzymes including carbonic anhydrase, aldose reductase, paraoxonase‐1,
α‐glycosi...
Effects of diallyl sulfide and zinc on testicular steroidogenesis in cadmium‐treated male rats
Tập 22 Số 5 - Trang 345-353 - 2008
AbstractCadmium (Cd) is one of the environmental pollutants that affect various
tissues and organs including testis. Harmful effect of cadmium on testis is
known to be germ cell degeneration and impairment of testicular steroidogenesis.
In the present study, the effect of diallyl sulfide (DAS), a sulfur‐containing
volatile compound present in garlic, and zinc (Zn) was investigated on
cadmium‐induc...
Protective effects of thymol on altered plasma lipid peroxidation and nonenzymic antioxidants in isoproterenol‐induced myocardial infarcted rats
Tập 26 Số 9 - Trang 368-373 - 2012
AbstractThis study evaluates the protective effects of thymol on altered plasma
lipid peroxidation products and nonenzymic antioxidants in isoproterenol
(ISO)‐induced myocardial infarcted rats. Male albino Wistar rats were pre and
cotreated with thymol (7.5 mg/kg body weight) daily for 7 days. ISO (100 mg/kg
body weight) was subcutaneously injected into rats on 6th and 7th day to induce
myocardial...
RETRACTED: Preventive effect of naringin on cardiac mitochondrial enzymes during isoproterenol‐induced myocardial infarction in rats: A transmission electron microscopic study
Tập 21 Số 6 - Trang 354-361 - 2007
AbstractDietary flavonoids intake has been reported inversely related to the
incidence of cardiovascular diseases (CVD). The present study is undertaken to
evaluate the preventive role of naringin on mitochondrial enzymes in
isoproterenol (ISO)‐induced myocardial infarction in male albino Wistar rats.
Rats subcutaneously injected with ISO (85 mg/kg) at an interval of 24 h for 2
days, resulting in ...
Cisplatin‐Induced Testicular Toxicity in Rats: The Protective Effect of Arjunolic Acid
Tập 28 Số 11 - Trang 515-521 - 2014
ABSTRACTIn the present study, the effect of arjunolic acid on testicular damage
induced by intraperitoneal injection of rats with 7 mg/kg cisplatin was studied.
Cisplatin induced a significant reduction in testicular weights, plasma
testosterone, and testicular reduced glutathione levels in addition to a
significant elevation of testicular malondialdehyde levels and testicular gene
expressions of ...
Dietary Antioxidant, Quercetin, Protects Sertoli‐Germ Cell Coculture from Atrazine‐Induced Oxidative Damage
Tập 26 Số 11 - Trang 477-485 - 2012
ABSTRACTQuercetin (QT), a dietary‐derived flavonoid, is ubiquitous in fruits and
vegetables and plays an important role in human health by virtue of its
antioxidant function. The present study was designed to examine the effects of
QT on oxidative damage that was induced by the herbicide, atrazine (ATZ), in
mixed cultures of Sertoli‐germ cells. Results showed that treatment with QT
increased cell ...
The effects of mesenchymal stem cell mitochondrial transplantation on doxorubicin‐mediated nephrotoxicity in rats
Tập 35 Số 1 - 2021
AbstractThe effect of dysfunctional mitochondria in several cell pathologies has
been reported in renal diseases, including diabetic nephropathy and acute kidney
injury. Previous studies have reported that mitochondrial transplantation
provided surprising results in myocardial and liver ischemia, as well as in
Parkinson's disease. We aimed to investigate the beneficial effects of isolated
mitochon...
A Comparison between the Nephrotoxic Profile of Gentamicin and Gentamicin Nanoparticles in Mice
Tập 29 Số 2 - Trang 57-62 - 2015
ABSTRACTAminoglycoside antibiotics are widely used against Gram‐negative
infections. On the other hand, nephrotoxicity is a deleterious side effect
associated with aminoglycoside therapy. Gentamicin is the most nephrotoxic
aminoglycoside. Because of serious health complications ensue the nephrotoxicity
induced by aminoglycosides, finding new therapeutic strategies against this
problem has a great ...