Journal of Biochemical and Molecular Toxicology
Công bố khoa học tiêu biểu
* Dữ liệu chỉ mang tính chất tham khảo
Sắp xếp:
Cisplatin‐Induced Testicular Toxicity in Rats: The Protective Effect of Arjunolic AcidABSTRACT In the present study, the effect of arjunolic acid on testicular damage induced by intraperitoneal injection of rats with 7 mg/kg cisplatin was studied. Cisplatin induced a significant reduction in testicular weights, plasma testosterone, and testicular reduced glutathione levels in addition to a significant elevation of testicular malondialdehyde levels an... ...
Journal of Biochemical and Molecular Toxicology - Tập 28 Số 11 - Trang 515-521 - 2014
RETRACTED: Protective effects of N‐acetyl cysteine on lipid peroxide metabolism on isoproterenol‐induced myocardial infarcted ratsAbstract The present study was designed to evaluate the preventive effects of N ‐acetyl cysteine on lipid peroxide metabolism in isoproterenol (ISO) induced myocardial infarcted rats. Male albino Wistar rats were pretreated with N ‐acetyl cysteine (5 and 10 mg/kg) daily for a period of 14 days. After the pretreatme... ...
Journal of Biochemical and Molecular Toxicology - Tập 25 Số 3 - Trang 151-157 - 2011
Protective effects of N‐acetyl cysteine on membrane‐bound adenosine triphosphatases and minerals in isoproterenol‐induced myocardial‐infarcted rats: An in vivo and in vitro studyAbstract The present study was aimed to evaluate the protective effects of N ‐acetyl cysteine (NAC) on changes in the activities/levels of adenosine triphosphatases and minerals in isoproterenol‐induced myocardial‐infarcted rats. Male albino Wistar rats were pretreated with NAC (10 mg/kg body weight) daily for a period of 14 days. After pre... ...
Journal of Biochemical and Molecular Toxicology - Tập 26 Số 7 - Trang 276-281 - 2012
RETRACTED: Preventive effect of naringin on cardiac mitochondrial enzymes during isoproterenol‐induced myocardial infarction in rats: A transmission electron microscopic studyAbstract Dietary flavonoids intake has been reported inversely related to the incidence of cardiovascular diseases (CVD). The present study is undertaken to evaluate the preventive role of naringin on mitochondrial enzymes in isoproterenol (ISO)‐induced myocardial infarction in male albino Wistar rats. Rats subcutaneously injected with ISO (85 mg/kg) at an interval ... ...
Journal of Biochemical and Molecular Toxicology - Tập 21 Số 6 - Trang 354-361 - 2007
Protective effects of thymol on altered plasma lipid peroxidation and nonenzymic antioxidants in isoproterenol‐induced myocardial infarcted ratsAbstract This study evaluates the protective effects of thymol on altered plasma lipid peroxidation products and nonenzymic antioxidants in isoproterenol (ISO)‐induced myocardial infarcted rats. Male albino Wistar rats were pre and cotreated with thymol (7.5 mg/kg body weight) daily for 7 days. ISO (100 mg/kg body weight) was subcutaneously injected into rats on 6th... ...
Journal of Biochemical and Molecular Toxicology - Tập 26 Số 9 - Trang 368-373 - 2012
Characterization of Cd‐induced molecular events prior to cellular damage in primary rat hepatocytes in culture: Activation of the stress activated signal protein JNK and transcription factor AP‐1Abstract The effect of Cadmium (Cd) on the expression of c‐Jun N ‐terminal kinase (JNK), c‐jun , and activator protein‐1 (AP‐1) has been investigated. We previously reported that Cd causes cell damage as indicated by increases in the cytotoxic parameters, lactate dehydrogenase and lipid peroxidation, and this damag... ...
Journal of Biochemical and Molecular Toxicology - Tập 18 Số 3 - Trang 133-142 - 2004
A Comparison between the Nephrotoxic Profile of Gentamicin and Gentamicin Nanoparticles in MiceABSTRACT Aminoglycoside antibiotics are widely used against Gram‐negative infections. On the other hand, nephrotoxicity is a deleterious side effect associated with aminoglycoside therapy. Gentamicin is the most nephrotoxic aminoglycoside. Because of serious health complications ensue the nephrotoxicity induced by aminoglycosides, finding new therapeutic strategies ... ...
Journal of Biochemical and Molecular Toxicology - Tập 29 Số 2 - Trang 57-62 - 2015
Genes of Innate Immunity and the Biological Response to Inhaled OzoneABSTRACT Ambient ozone has a significant impact on human health. We have made considerable progress in understanding the fundamental mechanisms that regulate the biological response to ozone. It is increasingly clear that genes of innate immunity play a central role in both infectious and noninfectious lung disease. The biological response to ambient ozone provides ... ...
Journal of Biochemical and Molecular Toxicology - Tập 27 Số 1 - Trang 3-16 - 2013
Proteomics analysis of liver samples from puffer fish Takifugu rubripes exposed to excessive fluoride: An insight into molecular response to fluorosisAbstract Comparative proteomics was performed to identify proteins in the liver of Takifugu rubripes in response to excessive fluoride exposure. Sixteen fish were randomly divided into a control group and an experimental group. The control group was raised in soft water alone (F− = 0.4 mg/L), and the experimental group... ...
Journal of Biochemical and Molecular Toxicology - Tập 24 Số 1 - Trang 21-28 - 2010
Molecular cloning and characterization of alpha‐class glutathione S‐transferase gene from the liver of silver carp, bighead carp, and other major chinese freshwater fishesAbstract Two full‐length cDNAs encoding glutathione S ‐transferase (GST) were cloned and sequenced from the hepatopancreas of planktivorous silver carp (Hypophthalmichthys molitrix ) and bighead carp (Aristichthys nobilis ). The silver carp and bighead carp GST cDNA were 920 and 978 bp in ... ...
Journal of Biochemical and Molecular Toxicology - Tập 20 Số 3 - Trang 114-126 - 2006
Tổng số: 32
- 1
- 2
- 3
- 4