Hippocampus
SCIE-ISI SCOPUS (1991-2025)
1098-1063
1050-9631
Mỹ
Cơ quản chủ quản: WILEY , Wiley-Liss Inc.
Lĩnh vực:
Cognitive Neuroscience
Các bài báo tiêu biểu
Phase relationship between hippocampal place units and the EEG theta rhythm
Tập 3 Số 3 - Trang 317-330 - 1993
AbstractMany complex spike cells in the hippocampus of the freely moving rat
have as their primary correlate the animal's location in an environment (place
cells). In contrast, the hippocampal electroer cephalograph theta pattern of
rhythmical waves (7–12 Hz) is better correlated with a class of movements that
change the rat's location in an environment. During movement through the place
field, th...
London taxi drivers and bus drivers: A structural MRI and neuropsychological analysis
Tập 16 Số 12 - Trang 1091-1101 - 2006
AbstractLicensed London taxi drivers show that humans have a remarkable capacity
to acquire and use knowledge of a large complex city to navigate within it. Gray
matter volume differences in the hippocampus relative to controls have been
reported to accompany this expertise. While these gray matter differences could
result from using and updating spatial representations, they might instead be
infl...
Hippocampal neurogenesis: Opposing effects of stress and antidepressant treatment
Tập 16 Số 3 - Trang 239-249 - 2006
AbstractThe hippocampus is one of several limbic brain structures implicated in
the pathophysiology and treatment of mood disorders. Preclinical and clinical
studies demonstrate that stress and depression lead to reductions of the total
volume of this structure and atrophy and loss of neurons in the adult
hippocampus. One of the cellular mechanisms that could account for alterations
of hippocampal...
Inverted‐U relationship between the level of peripheral corticosterone and the magnitude of hippocampal primed burst potentiation
Tập 2 Số 4 - Trang 421-430 - 1992
AbstractStudies have shown that peripheral levels of corticosterone correlate
with the magnitudes of two well‐described physiological models of memory,
long‐term potentiation (LTP) and primed burst (PB) potentiation. In the present
experiments, the authors investigated the effects of experimenter‐controlled
manipulations of the levels of corticosterone on the magnitude of hippocampal PB
potentiati...
Dual phase and rate coding in hippocampal place cells: Theoretical significance and relationship to entorhinal grid cells
Tập 15 Số 7 - Trang 853-866 - 2005
AbstractWe review the ideas and data behind the hypothesis that hippocampal
pyramidal cells encode information by their phase of firing relative to the
theta rhythm of the EEG. Particular focus is given to the further hypothesis
that variations in firing rate can encode information independently from that
encoded by firing phase. We discuss possible explanation of the phase‐precession
effect in te...
Recollection and familiarity: Examining controversial assumptions and new directions
Tập 20 Số 11 - Trang 1178-1194 - 2010
AbstractIt is well accepted that recognition memory reflects the contribution of
two separable memory retrieval processes, namely recollection and familiarity.
However, fundamental questions remain regarding the functional nature and neural
substrates of these processes. In this article, we describe a simple
quantitative model of recognition memory (i.e., the dual‐process signal
detection model) t...
Experience‐dependent modifications of hippocampal place cell firing
Tập 1 Số 2 - Trang 193-205 - 1991
AbstractUnderstanding the empirical rules that regulate alterations of
hippocampal firing fields will enhance our understanding of hippocampal
function. The current study sought to extend previous research in this area by
examining the effect of substituting a new stimulus for a familiar stimulus in a
familiar environment. Hippocampal place cells were recorded while rats chased
food pellets scatte...
The theta/gamma discrete phase code occuring during the hippocampal phase precession may be a more general brain coding scheme
Tập 15 Số 7 - Trang 913-922 - 2005
AbstractIn the hippocampus, oscillations in the theta and gamma frequency range
occur together and interact in several ways, indicating that they are part of a
common functional system. It is argued that these oscillations form a coding
scheme that is used in the hippocampus to organize the readout from long‐term
memory of the discrete sequence of upcoming places, as cued by current position.
This...
Topographically specific hippocampal projections target functionally distinct prefrontal areas in the rhesus monkey
Tập 5 Số 6 - Trang 511-533 - 1995
AbstractThe sources of ipsilateral projections from the hippocampal formation,
the presubiculum, area 29a‐c, and parasubiculum to medial, orbital, and lateral
prefrontal cortices were studied with retrograde tracers in 27 rhesus monkeys.
Labeled neurons within the hippocampal formation (CA1, CA1′, prosubiculum, and
subiculum) were found rostrally, although some were noted throughout the entire
ros...
Hippocampal volume and asymmetry in mild cognitive impairment and Alzheimer's disease: Meta‐analyses of MRI studies
Tập 19 Số 11 - Trang 1055-1064 - 2009
AbstractNumerous studies have reported a smaller hippocampal volume in
Alzheimer's disease (AD) patients than in aging controls. However, in mild
cognitive impairment (MCI), the results are inconsistent. Moreover, the
left‐right asymmetry of the hippocampus receives less research attention. In
this article, meta‐analyses are designed to determine the extent of hippocampal
atrophy in MCI and AD, an...