Hippocampus

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Memory‐related changes in L‐citrulline and agmatine in the rat brain
Hippocampus - Tập 19 Số 7 - Trang 597-602 - 2009
Ping Liu, Jing Yu, Nicola D. Collie, Sree Chary, Hu Zhang
AbstractL‐citrulline, L‐ornithine, and agmatine are the metabolites of L‐arginine by nitric oxide synthase (NOS), arginase, and arginine decarboxylase (ADC), respectively. In contrast to the NOS and arginase pathways, the role of the ADC‐agmatine pathway in learning and memory has only been paid attention lat...... hiện toàn bộ
Tyrosine phosphorylation of the GluR2 subunit is required for long‐term depression of synaptic efficacy in young animals in vivo
Hippocampus - Tập 17 Số 8 - Trang 600-605 - 2007
Christopher J. Fox, Kyle Russell, Andrea K. Titterness, Yu Tian Wang, Brian R. Christie
AbstractThe study of the intracellular mechanics that underlay changes in synaptic efficacy is a rapidly evolving field of research. It is currently believed that NMDA receptors play a significant role in the induction of synaptic plasticity, whereas AMPA receptors play a significant role in its expression. For AMPA receptors, it has been shown that tyrosine phosph...... hiện toàn bộ
Maturation of the hippocampal formation and amygdala in Macaca mulatta: A volumetric magnetic resonance imaging study
Hippocampus - Tập 20 Số 8 - Trang 922-935 - 2010
Christa Payne, Christopher J. Machado, Nancy G. Bliwise, Jocelyne Bachevalier
AbstractMalformations of the hippocampal formation and amygdala have been implicated in several neurodevelopmental disorders; yet relatively little is known about their normal structural development. The purpose of this study was to characterize the early developmental trajectories of the hippocampus and amygdala in the rhesus macaques (Macaca mulatta<...... hiện toàn bộ
Hippocampal neurogenesis: Opposing effects of stress and antidepressant treatment
Hippocampus - Tập 16 Số 3 - Trang 239-249 - 2006
Jennifer Warner‐Schmidt, Ronald S. Duman
AbstractThe hippocampus is one of several limbic brain structures implicated in the pathophysiology and treatment of mood disorders. Preclinical and clinical studies demonstrate that stress and depression lead to reductions of the total volume of this structure and atrophy and loss of neurons in the adult hippocampus. One of the cellular mechanisms that could accou...... hiện toàn bộ
Recollection and familiarity: Examining controversial assumptions and new directions
Hippocampus - Tập 20 Số 11 - Trang 1178-1194 - 2010
Andrew P. Yonelinas, Mariam Aly, Wei‐Chun Wang, Joshua D. Koen
AbstractIt is well accepted that recognition memory reflects the contribution of two separable memory retrieval processes, namely recollection and familiarity. However, fundamental questions remain regarding the functional nature and neural substrates of these processes. In this article, we describe a simple quantitative model of recognition memory (i.e., the dual‐...... hiện toàn bộ
Dynamic mapping of normal human hippocampal development
Hippocampus - Tập 16 Số 8 - Trang 664-672 - 2006
Nitin Gogtay, Tom Nugent, David Herman, Anna E. Ordóñez, Deanna Greenstein, Kiralee M. Hayashi, Liv Clasen, Arthur W. Toga, Jay N. Giedd, Judith L. Rapoport, Paul M. Thompson
AbstractThe hippocampus, which plays an important role in memory functions and emotional responses, has distinct subregions subserving different functions. Because the volume and shape of the hippocampus are altered in many neuropsychiatric disorders, it is important to understand the trajectory of normal hippocampal development. We present the first dynamic maps t...... hiện toàn bộ
Evidence for a specific role of the anterior hippocampal region in successful associative encoding
Hippocampus - Tập 17 Số 11 - Trang 1071-1080 - 2007
Elizabeth F. Chua, Daniel L. Schacter, Erin Rand‐Giovannetti, Reisa A. Sperling
AbstractIt has been well established that the hippocampal formation plays a critical role in the formation of memories. However, functional specialization within the hippocampus remains controversial. Using functional magnetic resonance imaging (fMRI) during a face‐name associative encoding task, followed by a postscan recognition test for face memory and face‐name...... hiện toàn bộ
Regional analysis of hippocampal activation during memory encoding and retrieval: fMRI study
Hippocampus - Tập 13 Số 1 - Trang 164-174 - 2003
Michael D. Greicius, Ben Krasnow, Jesse M Boyett-Anderson, Stéphan Eliez, Alan F. Schatzberg, Allan L. Reiss, Vinod Menon
AbstractInvestigators have recently begun to examine the differential role of subregions of the hippocampus in episodic memory. Two distinct models have gained prominence in the field. One model, outlined by Moser and Moser (Hippocampus 1998;8:608–619), based mainly on animal studies, has proposed that episodic memory is subserved by the posterior two‐thirds of the...... hiện toàn bộ
Distinct hippocampal regions make unique contributions to relational memory
Hippocampus - Tập 19 Số 2 - Trang 111-117 - 2009
Kelly S. Giovanello, David M. Schnyer, Mieke Verfaellie
AbstractNeuroscientific research has shown that the hippocampus is important for binding or linking together the various components of a learning event into an integrated memory. In a prior study, we demonstrated that the anterior hippocampus is involved in memory for the relations among informational elements to a greater extent that it is involved in memory for i...... hiện toàn bộ
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