Bioscience Reports
SCOPUS (1981-2023)SCIE-ISI
1573-4935
0144-8463
Cơ quản chủ quản: Portland Press, Ltd.
Lĩnh vực:
Cell BiologyBiophysicsBiochemistryMolecular Biology
Các bài báo tiêu biểu
Human mesenchymal stem cells - current trends and future prospectiveStem cells are cells specialized cell, capable of renewing themselves through cell division and can differentiate into multi-lineage cells. These cells are categorized as embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs) and adult stem cells. Mesenchymal stem cells (MSCs) are adult stem cells which can be isolated from human and animal sources. Human MSCs (hMSCs) are the ... ... hiện toàn bộ
Tập 35 Số 2 - 2015
Apoptosis and apoptotic body: disease message and therapeutic target potentialsAbstract Apoptosis is widely known as programmed cell death eliciting no inflammatory responses. The intricacy of apoptosis has been a focus of an array of researches, accumulating a wealth of knowledge which led to not only a better understanding of the fundamental process, but also potent therapies of diseases. The classic intrinsic and extrinsic signaling pathway... ... hiện toàn bộ
Tập 39 Số 1 - 2019
Na+, K+-ATPase Isozyme Diversity; Comparative Biochemistry and Physiological Implications of Novel Functional InteractionsNa+, K+-ATPase is ubiquitously expressed in the plasma membrane ofall animal cells where it serves as the principal regulator of intracellularion homeostasis. Na+, K+-ATPase is responsible for generating andmaintaining transmembrane ionic gradients that are of vital importance forcellular function and subservient activities such as volume regulation, pHmaintenance, and generation of action... ... hiện toàn bộ
Tập 20 Số 2 - Trang 51-91 - 2000
Chemical and Biological Parameters as Tools to Evaluate and Improve Heavy Metal PhytoremediationIn this review, chemical and biological parameters are discussed thatstrongly influence the speciation of heavy metals, their availability tobiological systems and, consequently, the possibilities to usebioremediation as a cleanup tool for heavy metal polluted sites. In orderto assess heavy metal availability, a need exists for rapid, cost-effectivesystems that reliably predict this parame... ... hiện toàn bộ
Tập 20 Số 4 - Trang 239-258 - 2000
Generating, Partitioning, Targeting and Functioning of Superoxide in MitochondriaRecently, we proposed a hypothetical model of coexistence of “Reactive oxygen cycle” with Q cycle and H+ cycle in mitochondrial respiratory chain to combine both processes of univalent electron leak for production of superoxide and of proton leak across inner mitochondrial membrane. This review presents a more detailed description of this model and summarizes the supporting experimental ev... ... hiện toàn bộ
Tập 17 Số 3 - Trang 259-272 - 1997
FOXA1: a transcription factor with parallel functions in development and cancerWhen aberrant, factors critical for organ morphogenesis are also commonly involved in disease progression. FOXA1 (forkhead box A1), also known as HNF3α (hepatocyte nuclear factor 3α), is required for postnatal survival due to its essential role in controlling pancreatic and renal function. In addition to regulating a variety of tissues during embryogenesis and early life, rescue experiment... ... hiện toàn bộ
Tập 32 Số 2 - Trang 113-130 - 2012
Hepcidin: regulation of the master iron regulatorIron, an essential nutrient, is required for many diverse biological processes. The absence of a defined pathway to excrete excess iron makes it essential for the body to regulate the amount of iron absorbed; a deficiency could lead to iron deficiency and an excess to iron overload and associated disorders such as anaemia and haemochromatosis respectively. This regulation is mediated by th... ... hiện toàn bộ
Tập 35 Số 3 - 2015
Abdominal obesity and colorectal cancer risk: systematic review and meta-analysis of prospective studiesThe association between abdominal obesity (as measured by waist circumference (WC) and waist-to-hip ratio (WHR)) and colorectal cancer (CRC) has not been fully quantified, and the magnitude of CRC risk associated with abdominal obesity is still unclear. A meta-analysis of prospective studies was performed to elucidate the CRC risk associated with abdominal obesity. Pubmed and Embase were s... ... hiện toàn bộ
Tập 37 Số 6 - 2017
Gene editing and CRISPR in the clinic: current and future perspectivesAbstract Genome editing technologies, particularly those based on zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and CRISPR (clustered regularly interspaced short palindromic repeat DNA sequences)/Cas9 are rapidly progressing into clinical trials. Most clinical use of CRISPR to date has focused on ex vivo gene editing of cell... ... hiện toàn bộ
Tập 40 Số 4 - 2020
Protein Detection Methods in Proteomics ResearchIn proteomics research chemical as well as physical methods are used to detect proteins subsequently to their separation. Physical methods are mostly applied after chromatography. They are either based on spectroscopy like light absorption at certain wavelengths or mass determination of peptides and their fragments with mass spectrometry. Chemical methods are used after two-dimensional ele... ... hiện toàn bộ
Tập 25 Số 1-2 - Trang 19-32 - 2005