Apoptosis and apoptotic body: disease message and therapeutic target potentials
Tóm tắt
Từ khóa
Tài liệu tham khảo
Kerr, 2002, History of the events leading to the formulation of the apoptosis concept, Toxicology, 181–182, 471, 10.1016/S0300-483X(02)00457-2
King, 1998, Cell cycle regulation and apoptosis, Annu. Rev. Physiol., 60, 601, 10.1146/annurev.physiol.60.1.601
Levine, 1997, p53, the cellular gatekeeper for growth and division, Cell, 88, 323, 10.1016/S0092-8674(00)81871-1
Gozuacik, 2004, Autophagy as a cell death and tumor suppressor mechanism, Oncogene, 23, 2891, 10.1038/sj.onc.1207521
Kerr, 1972, Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics, Br. J. Cancer, 26, 239, 10.1038/bjc.1972.33
Majno, 1995, Apoptosis, oncosis, and necrosis. An overview of cell death, Am. J. Pathol., 146, 3
Wang, 1997, p53 tumor-suppressor gene: clues to molecular carcinogenesis, J. Cell. Physiol., 173, 247, 10.1002/(SICI)1097-4652(199711)173:2%3c247::AID-JCP30%3e3.0.CO;2-A
Miyashita, 1994, Identification of a p53-dependent negative response element in the bcl-2 gene, Cancer Res., 54, 3131
Russell, 1995, Activation-induced death of mature T cells in the regulation of immune responses, Curr. Opin. Immunol., 7, 382, 10.1016/0952-7915(95)80114-6
Shiver, 1992, Cytotoxicity with target DNA breakdown by rat basophilic leukemia cells expressing both cytolysin and granzyme A, Cell, 71, 315, 10.1016/0092-8674(92)90359-K
Trapani, 2002, Functional significance of the perforin/granzyme cell death pathway, Nat. Rev. Immunol., 2, 735, 10.1038/nri911
Pietenpol, 2002, Cell cycle checkpoint signaling: cell cycle arrest versus apoptosis, Toxicology, 181–182, 475, 10.1016/S0300-483X(02)00460-2
Orlova-Fink, 2017, Preferential susceptibility of Th9 and Th2 CD4+ T cells to X4-tropic HIV-1 infection, AIDS, 31, 2211, 10.1097/QAD.0000000000001630
Garcia-Arriaza, 2017, HIV/AIDS vaccine candidates based on replication-competent recombinant poxvirus NYVAC-C-KC expressing trimeric gp140 and gag-derived virus-like particles or lacking the viral molecule B19 that inhibits type I interferon activate relevant HIV-1-specific B and T cell immune functions in nonhuman primates, J. Virol., 91, 10.1128/JVI.02182-16
Pitti, 1996, Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family, J. Biol. Chem., 271, 12687, 10.1074/jbc.271.22.12687
Pan, 1997, The receptor for the cytotoxic ligand TRAIL, Science, 276, 111, 10.1126/science.276.5309.111
Walczak, 1997, TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL, EMBO J., 16, 5386, 10.1093/emboj/16.17.5386
Takeda, 2001, Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells, Nat. Med., 7, 94, 10.1038/83416
Zhang, 2005, Mechanisms of resistance to TRAIL-induced apoptosis in cancer, Cancer Gene Ther., 12, 228, 10.1038/sj.cgt.7700792
Yao, 2012, Induction of non-small cell lung carcinoma apoptosis using soluble RGD-TRAIL by targeting the integrin receptor of tumor cells, Mol. Med. Rep., 6, 1355, 10.3892/mmr.2012.1071
Yu, 2014, DR4 specific TRAIL variants are more efficacious than wild-type TRAIL in pancreatic cancer, Cancer Biol. Ther., 15, 1658, 10.4161/15384047.2014.972183
Qiu, 2013, Annexin V-TRAIL fusion protein is a more sensitive and potent apoptotic inducer for cancer therapy, Sci. Rep., 3, 3565, 10.1038/srep03565
Batandier, 2004, Opening of the mitochondrial permeability transition pore induces reactive oxygen species production at the level of the respiratory chain complex I, J. Biol. Chem., 279, 17197, 10.1074/jbc.M310329200
Du, 2000, Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition, Cell, 102, 33, 10.1016/S0092-8674(00)00008-8
de Almagro, 2012, The inhibitor of apoptosis (IAP) proteins are critical regulators of signaling pathways and targets for anti-cancer therapy, Exp. Oncol., 34, 200
Garrido, 2006, Mechanisms of cytochrome c release from mitochondria, Cell Death Differ., 13, 1423, 10.1038/sj.cdd.4401950
Susin, 1999, Molecular characterization of mitochondrial apoptosis-inducing factor, Nature, 397, 441, 10.1038/17135
Joza, 2001, Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death, Nature, 410, 549, 10.1038/35069004
Pinkaew, 2017, Fortilin binds IRE1alpha and prevents ER stress from signaling apoptotic cell death, Nat. Commun., 8, 18, 10.1038/s41467-017-00029-1
Ghosh, 2015, Cross-talk between endoplasmic reticulum (ER) stress and the MEK/ERK pathway potentiates apoptosis in human triple negative breast carcinoma cells: role of a dihydropyrimidone, nifetepimine, J. Biol. Chem., 290, 3936, 10.1074/jbc.M114.594028
Humke, 1998, ERICE, a novel FLICE-activatable caspase, J. Biol. Chem., 273, 15702, 10.1074/jbc.273.25.15702
Koenig, 2001, Evidence that caspase-13 is not a human but a bovine gene, Biochem. Biophys. Res. Commun., 285, 1150, 10.1006/bbrc.2001.5315
Presland, 2009, Function of filaggrin and caspase-14 in formation and maintenance of the epithelial barrier, Dermatol. Sin., 27, 1
Slee, 2001, Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis, J. Biol. Chem., 276, 7320, 10.1074/jbc.M008363200
Tait, 2010, Mitochondria and cell death: outer membrane permeabilization and beyond, Nat. Rev. Mol. Cell Biol., 11, 621, 10.1038/nrm2952
Cory, 2002, The Bcl2 family: regulators of the cellular life-or-death switch, Nat. Rev. Cancer, 2, 647, 10.1038/nrc883
Miyashita, 1994, Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo, Oncogene, 9, 1799
Miyashita, 1995, Tumor-suppressor P53 is a direct transcriptional activator of the human bax gene, Cell, 80, 293, 10.1016/0092-8674(95)90412-3
Michelsen, 2007, The Crohn’s disease associated T cell co-stimulator Tl1a is induced by FC gamma receptor signaling but not by TLR ligands or pro-inflammatory cytokines in human monocytes and dendritic cells, Gastroenterology, 132, A32
Kobayashi, 2005, Spontaneous neutrophil apoptosis and regulation of cell survival by granulocyte macrophage-colony stimulating factor, J. Leukoc. Biol., 78, 1408, 10.1189/jlb.0605289
Wang, 2003, Direct and indirect induction of apoptosis in human mesenchymal stem cells in response to titanium particles, J. Orthop. Res., 21, 697, 10.1016/S0736-0266(02)00241-3
Perniok, 1998, High levels of circulating early apoptic peripheral blood mononuclear cells in systemic lupus erythematosus, Lupus, 7, 113, 10.1191/096120398678919804
Allina, 2006, T cell targeting and phagocytosis of apoptotic biliary epithelial cells in primary biliary cirrhosis, J. Autoimmun., 27, 232, 10.1016/j.jaut.2006.11.004
Clancy, 2006, Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block, J. Clin. Invest., 116, 2413
Lleo, 2007, Autophagy: highlighting a novel player in the autoimmunity scenario, J. Autoimmun., 29, 61, 10.1016/j.jaut.2007.06.003
Ruiz-Arguelles, 2007, Apoptosis of melanocytes in vitiligo results from antibody penetration, J. Autoimmun., 29, 281, 10.1016/j.jaut.2007.07.012
Salunga, 2007, Oxidative stress-induced apoptosis of bile duct cells in primary biliary cirrhosis, J. Autoimmun., 29, 78, 10.1016/j.jaut.2007.04.002
Scott, 2001, Phagocytosis and clearance of apoptotic cells is mediated by MER, Nature, 411, 207, 10.1038/35075603
Schrijvers, 2005, Phagocytosis of apoptotic cells by macrophages is impaired in atherosclerosis, Arterioscler. Thromb. Vasc. Biol., 25, 1256, 10.1161/01.ATV.0000166517.18801.a7
Mochizuki, 1996, Histochemical detection of apoptosis in Parkinson’s disease, J. Neurol. Sci., 137, 120, 10.1016/0022-510X(95)00336-Z
Vonmuhlen, 1995, Autoantibodies in the diagnosis of systemic rheumatic diseases, Semin. Arthritis Rheum., 24, 323, 10.1016/S0049-0172(95)80004-2
Gaipl, 2005, Impaired clearance of dying cells in systemic lupus erythematosus, Autoimmun. Rev., 4, 189, 10.1016/j.autrev.2004.10.007
Rieux-Laucat, 2003, Autoimmune lymphoproliferative syndromes: genetic defects of apoptosis pathways, Cell Death Differ., 10, 124, 10.1038/sj.cdd.4401190
Macchi, 2015, Role of inflammation and apoptosis in multiple sclerosis: comparative analysis between the periphery and the central nervous system, J. Neuroimmunol., 287, 80, 10.1016/j.jneuroim.2015.08.016
Sneller, 1997, Clinical, immunologic, and genetic features of an autoimmune lymphoproliferative syndrome associated with abnormal lymphocyte apoptosis, Blood, 89, 1341, 10.1182/blood.V89.4.1341
Watanabe-Fukunaga, 1992, Lymphoproliferation disorder in mice explained by defects in fas antigen that mediates apoptosis, Reprinted from Nature, 356, 314, 10.1038/356314a0
Thompson, 1995, Apoptosis in the pathogenesis and treatment of disease, Science, 267, 1456, 10.1126/science.7878464
Fevrier, 2011, CD4(+) T cell depletion in human immunodeficiency virus (HIV) infection: role of apoptosis, Viruses, 3, 586, 10.3390/v3050586
Abbate, 2006, Acute myocardial infarction and heart failure: role of apoptosis, Int. J. Biochem. Cell B, 38, 1834, 10.1016/j.biocel.2006.04.010
Sohn, 2007, Apoptosis during negative selection of autoreactive thymocytes, Curr. Opin. Immunol., 19, 510, 10.1016/j.coi.2007.06.001
Adams, 2007, Bcl-2-regulated apoptosis: mechanism and therapeutic potential, Curr. Opin. Immunol., 19, 488, 10.1016/j.coi.2007.05.004
Gustafsson, 2007, Bcl-2 family members and apoptosis, taken to heart, Am. J. Physiol. Cell Physiol., 292, C45, 10.1152/ajpcell.00229.2006
Hetts, 1998, To die or not to die – an overview of apoptosis and its role in disease, J. Am. Med. Assoc., 279, 300, 10.1001/jama.279.4.300
Lavrik, 2005, Caspases: pharmacological manipulation of cell death, J. Clin. Invest., 115, 2665, 10.1172/JCI26252
Wakelee, 2010, Phase I and pharmacokinetic study of lexatumumab (HGS-ETR2) given every 2 weeks in patients with advanced solid tumors, Ann. Oncol., 21, 376, 10.1093/annonc/mdp292
Soria, 2010, Phase 1b study of dulanermin (recombinant human Apo2L/TRAIL) in combination with paclitaxel, carboplatin, and bevacizumab in patients with advanced non-squamous non-small-cell lung cancer, J. Clin. Oncol., 28, 1527, 10.1200/JCO.2009.25.4847
Younes, 2010, A phase 1b/2 trial of mapatumumab in patients with relapsed/refractory non-Hodgkin’s lymphoma, Br. J. Cancer, 103, 1783, 10.1038/sj.bjc.6605987
Micheau, 2003, Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes, Cell, 114, 181, 10.1016/S0092-8674(03)00521-X
Schulze-Osthoff, 1998, Apoptosis signaling by death receptors, Eur. J. Biochem., 254, 439, 10.1046/j.1432-1327.1998.2540439.x
Meng, 2017, Anti-tumor effects of a recombinant anti-prostate specific membrane antigen immunotoxin against prostate cancer cells, BMC Urol., 17, 14, 10.1186/s12894-017-0203-9
Zhou, 2013, A novel recombinant immunocasp-6 fusion gene specifically and efficiently suppresses HER2-overexpressing osteosarcoma, Oncol. Rep., 29, 276, 10.3892/or.2012.2122
Hockings, 2015, Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax, Cell Death Dis., 6, e1735, 10.1038/cddis.2015.105
Prabhu, 2017, Targeting of X-linked inhibitor of apoptosis protein and PI3-kinase/AKT signaling by embelin suppresses growth of leukemic cells, PLoS One, 12, e0180895, 10.1371/journal.pone.0180895
Carter, 2011, XIAP antisense oligonucleotide (AEG35156) achieves target knockdown and induces apoptosis preferentially in CD34+38− cells in a phase 1/2 study of patients with relapsed/refractory AML, Apoptosis, 16, 67, 10.1007/s10495-010-0545-1
Bai, 2014, Small-molecule SMAC mimetics as new cancer therapeutics, Pharmacol. Ther., 144, 82, 10.1016/j.pharmthera.2014.05.007
Park, 2008, Discovery of an orally bioavailable small molecule inhibitor of prosurvival B-cell lymphoma 2 proteins, J. Med. Chem., 51, 6902, 10.1021/jm800669s
Thomas, 2013, Targeting the Bcl-2 family for cancer therapy, Expert Opin. Ther. Targets, 17, 61, 10.1517/14728222.2013.733001
Zhang, 2017, Pazopanib, a novel multi-kinase inhibitor, shows potent antitumor activity in colon cancer through PUMA-mediated apoptosis, Oncotarget, 8, 3289, 10.18632/oncotarget.13753
Zhang, 2013, An update on antitumor activity of naturally occurring chalcones, Evid. Based Complement Alternat. Med., 2013, 815621
Marqus, 2017, Evaluation of the use of therapeutic peptides for cancer treatment, J. Biomed. Sci., 24, 21, 10.1186/s12929-017-0328-x
Ravichandran, 2011, Beginnings of a good apoptotic meal: the find-me and eat-me signaling pathways, Immunity, 35, 445, 10.1016/j.immuni.2011.09.004
Thery, 2002, Exosomes: composition, biogenesis and function, Nat. Rev. Immunol., 2, 569, 10.1038/nri855
Morel, 2011, Cellular mechanisms underlying the formation of circulating microparticles, Arterioscler. Thromb. Vas., 31, 15, 10.1161/ATVBAHA.109.200956
Atkin-Smith, 2015, A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure, Nat. Commun., 6, 10.1038/ncomms8439
Wickman, 2012, How apoptotic cells aid in the removal of their own cold dead bodies, Cell Death Differ., 19, 735, 10.1038/cdd.2012.25
Charras, 2005, Non-equilibration of hydrostatic pressure in blebbing cells, Nature, 435, 365, 10.1038/nature03550
Barros, 2003, Apoptotic and necrotic blebs in epithelial cells display similar neck diameters but different kinase dependency, Cell Death Differ., 10, 687, 10.1038/sj.cdd.4401236
Croft, 2005, Actin-myosin-based contraction is responsible for apoptotic nuclear disintegration, J. Cell Biol., 168, 245, 10.1083/jcb.200409049
Nunez, 2010, Apoptotic volume decrease as a geometric determinant for cell dismantling into apoptotic bodies, Cell Death Differ., 17, 1665, 10.1038/cdd.2010.96
Bortner, 2008, Cationic gradient reversal and cytoskeleton-independent volume regulatory pathways define an early stage of apoptosis, J. Biol. Chem., 283, 7219, 10.1074/jbc.M707809200
Orlando, 2006, Rho kinase regulates fragmentation and phagocytosis of apoptotic cells, Exp. Cell Res., 312, 5, 10.1016/j.yexcr.2005.09.012
Lane, 2005, Active relocation of chromatin and endoplasmic reticulum into blebs in late apoptotic cells, J. Cell Sci., 118, 4059, 10.1242/jcs.02529
Peter, 2008, Migration to apoptotic “find-me” signals is mediated via the phagocyte receptor G2A, J. Biol. Chem., 283, 5296, 10.1074/jbc.M706586200
D’mello, 2009, The urokinase plasminogen activator receptor promotes efferocytosis of apoptotic cells, J. Biol. Chem., 284, 17030, 10.1074/jbc.M109.010066
Gardai, 2006, Recognition ligands on apoptotic cells: a perspective, J. Leukoc. Biol., 79, 896, 10.1189/jlb.1005550
Kinchen, 2008, A pathway for phagosome maturation during engulfment of apoptotic cells, Nat. Cell Biol., 10, 556, 10.1038/ncb1718
Gerke, 2002, Annexins: from structure to function, Physiol. Rev., 82, 331, 10.1152/physrev.00030.2001
Yang, 2001, In vivo and in vitro measurement of apoptosis in breast cancer cells using Tc-99m-EC-annexin V, Cancer Biother. Radiopharm., 16, 73, 10.1089/108497801750096087
Rottey, 2007, Tc-99m-HYNIC Annexin-V imaging of tumors and its relationship to response to radiotherapy and/or chemotherapy, Q. J. Nucl. Med. Mol. Imaging, 51, 182
Kurihara, 2008, Imaging and dosimetry of Tc-99m EC annexin V: preliminary clinical study targeting apoptosis in breast tumors, Appl. Radiat. Isot., 66, 1175, 10.1016/j.apradiso.2008.01.012
Orlando, 2006, Rho kinase regulates phagocytosis, surface expression of GlcNAc, and Golgi fragmentation of apoptotic PC12 cells, Exp. Cell Res., 312, 3298, 10.1016/j.yexcr.2006.06.033
Witasp, 2007, Bridge over troubled water: milk fat globule epidermal growth factor 8 promotes human monocyte-derived macrophage clearance of non-blebbing phosphatidylserine-positive target cells, Cell Death Differ., 14, 1063, 10.1038/sj.cdd.4402096
Buzas, 2014, Emerging role of extracellular vesicles in inflammatory diseases, Nat. Rev. Rheumatol., 10, 356, 10.1038/nrrheum.2014.19
Moss, 2006, A novel role for microtubules in apoptotic chromatin dynamics and cellular fragmentation, J. Cell Sci., 119, 2362, 10.1242/jcs.02959
Holmgren, 1999, Horizontal transfer of DNA by the uptake of apoptotic bodies, Blood, 93, 3956, 10.1182/blood.V93.11.3956.411k05_3956_3963
Bergsmedh, 2001, Horizontal transfer of oncogenes by uptake of apoptotic bodies, Proc. Natl. Acad. Sci. U.S.A., 98, 6407, 10.1073/pnas.101129998
Zernecke, 2009, Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection, Sci. Signal., 2, ra81, 10.1126/scisignal.2000610
Halicka, 2000, Segregation of RNA and separate packaging of DNA and RNA in apoptotic bodies during apoptosis, Exp. Cell Res., 260, 248, 10.1006/excr.2000.5027
Turiak, 2011, Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice, J. Proteomics, 74, 2025, 10.1016/j.jprot.2011.05.023
Lleo, 2014, Shotgun proteomics: identification of unique protein profiles of apoptotic bodies from biliary epithelial cells, Hepatology, 60, 1314, 10.1002/hep.27230
Casciola-Rosen, 1994, Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes, J. Exp. Med., 179, 1317, 10.1084/jem.179.4.1317
Tran, 2002, Subcellular redistribution of la/SSB autoantigen during physiologic apoptosis in the fetal mouse heart and conduction system: a clue to the pathogenesis of congenital heart block, Arthritis Rheum., 46, 202, 10.1002/1529-0131(200201)46:1%3c202::AID-ART10062%3e3.0.CO;2-Y
Berda-Haddad, 2011, Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1alpha, Proc. Natl. Acad. Sci. U.S.A., 108, 20684, 10.1073/pnas.1116848108
Rubartelli, 1997, The selective engulfment of apoptotic bodies by dendritic cells is mediated by the alpha(v)beta3 integrin and requires intracellular and extracellular calcium, Eur. J. Immunol., 27, 1893, 10.1002/eji.1830270812
Albert, 1998, Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs, Nature, 392, 86, 10.1038/32183
Li, 2014, Anti-inflammatory response following uptake of apoptotic bodies by meningothelial cells, J. Neuroinflammation, 11, 35, 10.1186/1742-2094-11-35
Kogianni, 2008, Apoptotic bodies convey activity capable of initiating osteoclastogenesis and localized bone destruction, J. Bone Miner. Res., 23, 915, 10.1359/jbmr.080207
Schiller, 2008, Autoantigens are translocated into small apoptotic bodies during early stages of apoptosis, Cell Death Differ., 15, 183, 10.1038/sj.cdd.4402239
Jiang, 2009, Apoptotic body engulfment by hepatic stellate cells promotes their survival by the JAK/STAT and Akt/NF-kappa B-dependent pathways, J. Hepatol., 51, 139, 10.1016/j.jhep.2009.03.024
Marin-Gallen, 2010, Dendritic cells pulsed with antigen-specific apoptotic bodies prevent experimental type 1 diabetes, Clin. Exp. Immunol., 160, 207, 10.1111/j.1365-2249.2009.04082.x
Singh, 2012, Tubular cell HIV-entry through apoptosed CD4 T cells: a novel pathway, Virology, 434, 68, 10.1016/j.virol.2012.09.009
Kranich, 2010, Engulfment of cerebral apoptotic bodies controls the course of prion disease in a mouse strain-dependent manner, J. Exp. Med., 207, 2271, 10.1084/jem.20092401
Samos, 2006, Circulating nucleic acids in plasma/serum and tumor progression – are apoptotic bodies involved? An experimental study in a rat cancer model, Ann. N. Y. Acad. Sci., 1075, 165, 10.1196/annals.1368.022
Bergsmedh, 2001, Horizontal transfer of oncogenes by uptake of apoptotic bodies, Proc. Natl. Acad. Sci. U.S.A., 98, 6407, 10.1073/pnas.101129998
Wiley, 2006, Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection, Proc. Natl. Acad. Sci. U.S.A., 103, 738, 10.1073/pnas.0507995103
Izquierdo-Useros, 2010, HIV and mature dendritic cells: Trojan exosomes riding the Trojan horse?, PLoS Pathog., 6, 10.1371/journal.ppat.1000740
Poon, 2014, Unexpected link between an antibiotic, pannexin channels and apoptosis, Nature, 507, 329, 10.1038/nature13147