Bioscience Reports

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The Behaviour of Ions in Narrow Water-Filled Pores
Bioscience Reports - Tập 18 - Trang 313-327 - 1998
D. T. Edmonds
Today, the equilibrium behavior of ions in solution may be predicted with some confidence, essentially because rapid ionic diffusion over small distances ensures homogeneity throughout the solution. Equilibrium concepts such as ionic strength and pH apply. However, when attempting to understand the behavior of ions passing rapidly through narrow pores such as ion channels, no such equilibrium stat...... hiện toàn bộ
MicroRNA 486-3P as a stability marker in acute coronary syndrome
Bioscience Reports - Tập 36 Số 3 - 2016
Tianling Wei, Lasse Folkersen, Ewa Ehrenborg, Anders Gabrielsen
Easily accessible biomarkers are needed to diagnose cardiovascular disease precisely—particularly, to distinguish between disease subtypes that are encountered in clinical practice. Per the hypothesis that plasma miRNA is valuable for this purpose, we performed complete transcriptional profiling of an miRNA discovery-set in 14 samples: three patients with ST-elevated acute myocardial infar...... hiện toàn bộ
Acetoacetyl-CoA ligase activity in the isolated rat hepatocyte: Effects of 25-hydroxycholesterol and high density lipoprotein
Bioscience Reports - Tập 7 - Trang 217-224 - 1987
Gail A. Wong, James D. Bergstrom, John Edmond
The activity of acetoacetyl-CoA (AcAc-CoA) ligase (E.C.6.2.1.16) in hepatocytes from rats was shown to be the same as the activity in homogenates of their livers. In hepatocytes treated with 25-hydroxycholesterol, AcAc-CoA ligase, 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase and rates of sterol synthesis were substantially decreased. Hepatocytes treated with high density lipoprotein (HDL) e...... hiện toàn bộ
Effects of mitogenic agents upon glucocorticoid action in human tonsillar T-lymphocytes
Bioscience Reports - Tập 10 Số 1 - Trang 69-72 - 1990
Soner Altiok, Engin Bermek
The treatment of human tonsillar T-lymphocytes with 4-phorbol 12-myristate 13-acetate (PMA), resulted in about two fold increase in glucocorticoid receptor (GR) number, without any significant change in the receptor affinity. This increase disappeared in the presence of cycloheximide.Alone, PMA and calcium inophore A23187 did not affect, but together stimulated, like phyto...... hiện toàn bộ
Oligomeric forms of potato spindle tuber viroid (PSTV) and of its complementary RNA are present in nuclei isolated from viroid-infected potato cells
Bioscience Reports - Tập 3 Số 8 - Trang 767-774 - 1983
Ellen Spiesmacher, Hans‐Peter Mühlbach, Martina Schnölzer, Bernd Haas, Heinz L. Sänger
Different oligomeric forms of PSTV are detected in nuclei isolated from PSTV-infected potato cells by means of molecular hybridization, using as probes synthetic oligodeoxyribonucleotides with sequence specificity for (+)PSTV and for (−)PSTV. In addition to several species of longer-than-unit-length (−)PSTV molecules, two oligomeric forms os (+)PSTV are detected, which correspond in size t...... hiện toàn bộ
Isolation of riboflavin carrier proteins from pregnant human and umbilical cord serum: Similarities with chicken egg riboflavin carrier protein
Bioscience Reports - Tập 7 - Trang 563-571 - 1987
Sandhya S. Visweswariah, P. Radhakantha Adiga
A riboflavin carrier protein has been purified from human pregnancy and umbilical cord sera by affinity chromatography and fast protein liquid chromatography. This protein has a similar molecular weight to the chicken egg riboflavin carrier protein and shares other physicochemical properties, such as pI and riboflavin binding characteristics, with the avian counterpart. A high degree of immunologi...... hiện toàn bộ
Heparin inhibits specific glycosyltransferase activities in interleukin 2 activated murine T cells
Bioscience Reports - - 1988
Gerald A. Schwarting, Anna Gajewski
In order to better understand the role of cell surface glycolipids in T lymphocyte activation, heparin was used to simultaneously modulate the expression of glycolipids and the lytic capacity of lymphocytes activated by interleukin-2. Results presented here show that heparin added at the start of a 3 day culture inhibited the formation of lymphokine activated killer cells by up to 50%. Hep...... hiện toàn bộ
Novel application of quantitative immunoassays for screening seed globulins of cowpea varieties
Bioscience Reports - Tập 5 - Trang 673-681 - 1985
M. R. Mawal, S. A. Ranade, Y. R. Mawal, S. N. Ranadive, A. Bhattacharya, P. K. Ranjekar
Using antibodies raised in rabbits, radioimmunoassay (RIA) and enzyme-linked immunosorbent assay (ELISA) are standardized for cowpea (var. Pusa Barsati) seed globulins. The RIA, when used to screen three stages of seed development, reveals that maximum globulins are detected at 28 days after flowering. When three different varieties of cowpea are assayed for their globulin content by RIA and ELISA...... hiện toàn bộ
Amino acid sequence and structural repeats in schistosome paramyosin match those of myosin
Bioscience Reports - Tập 7 - Trang 11-16 - 1987
Carolyn Cohen, David E. Lanar, David A. D. Parry
The cDNA encoding about half of an antigenic non-surface schistosome parasite protein of M r 97 K has recently been cloned and sequenced (Lanar, Pearce, James and Sher (1986)Science 234:593–596). Analysis of this sequence, together with the properties of the native protein, reveals that this protein is paramyosin, the hitherto unsequenced core protein of myosin f...... hiện toàn bộ
Characterization of a membrane-specific tubulin isoform by peptide mapping
Bioscience Reports - Tập 6 - Trang 913-919 - 1986
Alan J. Hargreaves, Jesus Avila
A membrane-specific tubulin-like protein, found in preparations of synaptic plasma membranes and brain mitochondria, was analyzed by chemical and proteolytic peptide mapping to determine which part of the molecule was different from cytoplasmic tubulin. The membrane polypeptide was identical to alpha tubulin in the first two-thirds of the molecule containing the amino terminal, as found by peptide...... hiện toàn bộ
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