The Behaviour of Ions in Narrow Water-Filled PoresBioscience Reports - Tập 18 - Trang 313-327 - 1998
D. T. Edmonds
Today, the equilibrium behavior of ions in solution may be predicted with some confidence, essentially because rapid ionic diffusion over small distances ensures homogeneity throughout the solution. Equilibrium concepts such as ionic strength and pH apply. However, when attempting to understand the behavior of ions passing rapidly through narrow pores such as ion channels, no such equilibrium stat...... hiện toàn bộ
MicroRNA 486-3P as a stability marker in acute coronary syndromeBioscience Reports - Tập 36 Số 3 - 2016
Tianling Wei, Lasse Folkersen, Ewa Ehrenborg, Anders Gabrielsen
Easily accessible biomarkers are needed to diagnose cardiovascular disease precisely—particularly, to distinguish between disease subtypes that are encountered in clinical practice. Per the hypothesis that plasma miRNA is valuable for this purpose, we performed complete transcriptional profiling of an miRNA discovery-set in 14 samples: three patients with ST-elevated acute myocardial infar...... hiện toàn bộ
Acetoacetyl-CoA ligase activity in the isolated rat hepatocyte: Effects of 25-hydroxycholesterol and high density lipoproteinBioscience Reports - Tập 7 - Trang 217-224 - 1987
Gail A. Wong, James D. Bergstrom, John Edmond
The activity of acetoacetyl-CoA (AcAc-CoA) ligase (E.C.6.2.1.16) in hepatocytes from rats was shown to be the same as the activity in homogenates of their livers. In hepatocytes treated with 25-hydroxycholesterol, AcAc-CoA ligase, 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase and rates of sterol synthesis were substantially decreased. Hepatocytes treated with high density lipoprotein (HDL) e...... hiện toàn bộ
Studies of nucleotides of growth-plate cartilage: evidence linking changes in cellular metabolism with cartilage calcificationBioscience Reports - Tập 3 - Trang 345-351 - 1983
Irving M. Shapiro, Ellis E. Golub, Mary May, Joseph L. Rabinowitz
The objective of this study was to examine the nucleotides of chick growth-plate cartilage and to measure the concentration of adenine nucleotides in the pre-mineralizing and mineralizing zones. Nucleotides were isolated from the two regions using a rapid-freezing technique and the concentration of individual components was ascertained by HPLC. The actual values of ATP, ADP, and other nucleotides ...... hiện toàn bộ
Lateral diffusion of PDGF β-receptors in human fibroblastsBioscience Reports - Tập 11 Số 1 - Trang 43-52 - 1991
Pia Ljungquist-Höddelius, Margareta Lirvall, Åke Wasteson, Karl‐Eric Magnusson
When platelet-derived growth factor (PDGF) binds to its receptors a number of biochemical reactions are elicited in the cell. Several models have been presented for the effects of ligand-induced receptor conformation and aggregation on signal transduction but little is known about the direct effects on receptor diffusion. This study concerns the lateral mobility of PDGF receptors in fibrob...... hiện toàn bộ
Effects of mitogenic agents upon glucocorticoid action in human tonsillar T-lymphocytesBioscience Reports - Tập 10 Số 1 - Trang 69-72 - 1990
Soner Altiok, Engin Bermek
The treatment of human tonsillar T-lymphocytes with 4-phorbol 12-myristate 13-acetate (PMA), resulted in about two fold increase in glucocorticoid receptor (GR) number, without any significant change in the receptor affinity. This increase disappeared in the presence of cycloheximide.Alone, PMA and calcium inophore A23187 did not affect, but together stimulated, like phyto...... hiện toàn bộ
Short-term inhibition of the energy metabolism affects motility but not surface properties of sperm cellsBioscience Reports - Tập 16 - Trang 35-40 - 1996
M. L. Pascual, J. A. Cebrian-Perez, M. J. Lopez-Perez, T. Muiño-Blanco
Centrifugal countercurrent distribution (CCCD) in aqueous two-phase systems has been proven to be a useful method to study subtle surface properties of spermatozoa. The present work shows that a short-term inhibition of the energy metabolism of sperm cells effected by incubating bovine sperm cells with KCN or ouabain, did not account for changes in the cell surface properties, as assessed either b...... hiện toàn bộ