1State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, 19 Zhongguancun Rd. Haidian, Beijing 100080, China.
Tóm tắt
Recently, we proposed a hypothetical model of coexistence of “Reactive oxygen cycle” with Q cycle and H+ cycle in mitochondrial respiratory chain to combine both processes of univalent electron leak for production of superoxide and of proton leak across inner mitochondrial membrane. This review presents a more detailed description of this model and summarizes the supporting experimental evidence obtained.
