Biomedical Chromatography
SCOPUS (1986-2023)SCIE-ISI
1099-0801
0269-3879
Anh Quốc
Cơ quản chủ quản: WILEY , John Wiley and Sons Ltd
Lĩnh vực:
Clinical BiochemistryAnalytical ChemistryBiochemistryDrug DiscoveryMolecular BiologyPharmacologyMedicine (miscellaneous)
Các bài báo tiêu biểu
Rapid screening and identification of α‐glucosidase inhibitors from mulberry leaves using enzyme‐immobilized magnetic beads coupled with HPLC/MS and NMRABSTRACT α ‐Glucosidase plays important roles in the digestion and absorption of carbohydrates in the small intestine. The inhibition of α ‐glucosidase is regarded as a potential way to treat diabetes. We established an approach to screening α ‐glucosidase inhibitors from medicinal plants ...
Tập 27 Số 2 - Trang 148-155 - 2013
Systematic LC‐MS/MS bioanalytical method development that incorporates plasma phospholipids risk avoidance, usage of incurred sample and well thought‐out chromatographyAbstract This treatise summarizes the underlying principle and the road map for systematic LC‐MS/MS bioanalytical method development. The three themes that have recently emerged as central to building quality during method development—phospholipids, incurred sample and sound chromatographic considerations—are the main focus of this article. In order to reduce the bi... ... hiện toàn bộ
Tập 24 Số 1 - Trang 2-19 - 2010
Derivatization reagents in liquid chromatography/electrospray ionization tandem mass spectrometryAbstract Liquid chromatography/electrospray ionization tandem mass spectrometry (LC/ESI‐MS/MS) is one of the most prominent analytical techniques owing to its inherent selectivity and sensitivity. In LC/ESI‐MS/MS, chemical derivatization is often used to enhance the detection sensitivity. Derivatization improves the chromatographic separation, and enhances the mass ... ... hiện toàn bộ
Tập 25 Số 1-2 - Trang 1-10 - 2011
Salting‐out assisted liquid/liquid extraction with acetonitrile: a new high throughput sample preparation technique for good laboratory practice bioanalysis using liquid chromatography–mass spectrometryAbstract Acetonitrile, an organic solvent miscible with aqueous phase, has seen thousands of publications in the literature as an efficient deproteinization reagent. The use of acetonitrile for liquid–liquid extraction (LLE), however, has seen very limited application due to its miscibility with aqueous phase. The interest in LLE with acetonitrile has been pursued a... ... hiện toàn bộ
Tập 23 Số 4 - Trang 419-425 - 2009
Enantioseparation of some clinically used drugs by HPLC using cellulose Tris (3,5‐dichlorophenylcarbamate) chiral stationary phaseAbstract The chiral resolution of some clinically used drugs namely metoprolol, teratolol, tolamolol, nebivolol (β‐adrenergic blockers), econazole, miconazole (anti‐fungal agents), cromakalim (anti‐hypertensive agent) and etodolac (anti‐inflammatory agent) was achieved on cellulose tris (3,5‐dichlorophenylcarbamate) chiral stationary phase. The mobile phase used was... ... hiện toàn bộ
Tập 17 Số 2-3 - Trang 113-117 - 2003
Simplifying sample preparation using fabric phase sorptive extraction technique for the determination of benzodiazepines in blood serum by high‐performance liquid chromatographyAbstract Fabric phase sorptive extraction (FPSE), a recently introduced novel sample preparation technology, has been evaluated for the extraction of benzodiazepines from human blood serum. FPSE utilizes a flexible fabric surface as the substrate platform for creating sol‐gel hybrid organic‐inorganic sorbent coatings. FPSE media can be introduced directly into the s... ... hiện toàn bộ
Tập 30 Số 6 - Trang 829-836 - 2016
Enantiomeric separation of 2‐arylpropionic acid nonsteroidal anti‐inflammatory drugs by HPLC with hydroxypropyl‐β‐cyclodextrin as chiral mobile phase additiveAbstract The enantio‐separations of eight 2‐arylpropionic acid nonsteroidal anti‐inflammatory drugs (2‐APA NSAIDs) were established using reversed‐phase high‐performance liquid chromatography with hydroxypropyl‐β ‐cyclodextrin (HP‐β ‐CD) as chiral mobile phase additive for studying the stereoselective skin permeati... ... hiện toàn bộ
Tập 24 Số 8 - Trang 799-807 - 2010
Structural characterization by chromatographic profiling of the oligosaccharides of human immunodeficiency virus (HIV) recombinant envelope glycoprotein gp120 produced in chinese hamster ovary cellsAbstract This report together with the paper by T. Mizuochi, M. W. Spellman, M. Larkin, J. Solomon, L. J. Basa and T. Feizi (1988) Biochem. J. 254, 599–603 describes the structural elucidation of the N ‐linked oligosaccharides of the HIV envelope glycoprotein, gp120 (cloned from the HTLV‐III B isolate and expresse... ... hiện toàn bộ
Tập 2 Số 6 - Trang 260-270 - 1987
Applicability of bioanalysis of multiple analytes in drug discovery and development: review of select case studies including assay development considerations
Tập 20 Số 5 - Trang 383-414 - 2006
Định lượng đồng thời atorvastatin và các chất chuyển hóa hoạt động trong huyết tương người bằng phương pháp sắc ký lỏng-khối phổ kế phối hợp sử dụng rosuvastatin làm chuẩn nội Dịch bởi AI Tóm tắt Phương pháp sắc ký lỏng-khối phổ kép (LC-MS/MS) đơn giản, nhạy cảm, chọn lọc và nhanh chóng đã được phát triển và xác thực để định lượng atorvastatin và các chất chuyển hóa hoạt động ortho -hydroxyatorvastatin và para -hydroxyatorvastatin trong huyết tương người sử dụng rosuvastatin làm chuẩn nội (IS). Sau ... ... hiện toàn bộ
Tập 20 Số 9 - Trang 924-936 - 2006
#Phương pháp sắc ký lỏng-khối phổ phối hợp #định lượng atorvastatin #chất chuyển hóa <jats:italic>ortho</jats:italic>-hydroxyatorvastatin #<jats:italic>para</jats:italic>-hydroxyatorvastatin #chuẩn nội rosuvastatin #huyết tương người.