Jiwoon Jeong, Jung Hun Kim, Jung Hee Shim, Nathaniel S. Hwang, Chan Yeong Heo
Abstract Background Bone regeneration involves various complex biological
processes. Many experiments have been performed using biomaterials in vivo and
in vitro to promote and understand bone regeneration. Among the many
biomaterials, calcium phosphates which exist in the natural bone have been
conducted a number of studies because of its bone regenerative property. It can
be directly contributed... hiện toàn bộ
Abstract Background The electrochemical biosensor is one of the typical sensing
devices based on transducing the biochemical events to electrical signals. In
this type of sensor, an electrode is a key component that is employed as a solid
support for immobilization of biomolecules and electron movement. Thanks to
numerous nanomaterials that possess the large surface area, synergic effects are
enab... hiện toàn bộ
Abstract Background Polymeric drug delivery systems have been achieved great
development in the last two decades. Polymeric drug delivery has defined as a
formulation or a device that enables the introduction of a therapeutic substance
into the body. Biodegradable and bio-reducible polymers make the magic possible
choice for lot of new drug delivery systems. The future prospects of the
research fo... hiện toàn bộ
Zeeshan Sheikh, Nader Hamdan, Yuichi Ikeda, Marc D. Grynpas, Bernhard Ganß, Michael Glogauer
Abstract Periodontal disease is categorized by the destruction of periodontal
tissues. Over the years, there have been several clinical techniques and
material options that been investigated for periodontal defect
repair/regeneration. The development of improved biomaterials for periodontal
tissue engineering has significantly improved the available treatment options
and their clinical results. Bo... hiện toàn bộ
Abstract Recently, electrical stimulation as a physical stimulus draws lots of
attention. It shows great potential in disease treatment, wound healing, and
mechanism study because of significant experimental performance. Electrical
stimulation can activate many intracellular signaling pathways, and influence
intracellular microenvironment, as a result, affect cell migration, cell
proliferation, an... hiện toàn bộ
Abstract Background Cancer is one of the deadliest threats to human health.
Abnormal physiochemical conditions and dysregulated biosynthetic intermediates
in the tumor microenvironment (TME) play a significant role in modulating cancer
cells to evade or defend conventional anti-cancer therapy such as surgery,
chemotherapy and radiotherapy. One of the most important challenges in the
development of... hiện toàn bộ
K. C. Gupta, Adnan Haider, Yuri Choi, Inn‐Kyu Kang
Abstract Nanofibrous scaffolds are artificial extracellular matrices which
provide natural environment for tissue formation. In comparison to other forms
of scaffolds, the nanofibrous scaffolds promote cell adhesion, proliferation and
differentiation more efficiently due to having high surface to volume ratio.
Although scaffolds for tissue engineering have been fabricated by various
techniques but... hiện toàn bộ
Abstract Background Total hip arthroplasty (THA) is probably one of the most
successful surgical interventions performed in medicine. Through the revolution
of hip arthroplasty by principles of low friction arthroplasty was introduced by
Sir John Charnley in 1960s. Thereafter, new bearing materials, fixation methods,
and new designs has been improved. The main concern regarding failure of THA has
... hiện toàn bộ
Julián Quintero Quiroz, Natalia María Tascón Acevedo, Jenniffer Zapata-Giraldo, Luz Elena Botero, Diana Zárate-Triviño, Jorge Saldarriaga, Vera Z. Pérez
Abstract Background Chemical reduction has become an accessible and useful
alternative to obtain silver nanoparticles (AgNPs). However, its toxicity
capacity depends on multiple variables that generate differences in the ability
to inhibit the growth of microorganisms. Thus, optimazing parameters for the
synthesis of AgNPs can increase its antimicrobial capacity by improving its
physical-chemical ... hiện toàn bộ
Mona Sari, Puspa Hening, Chotimah, Ika Dewi Ana, Yusril Yusuf
Abstract Background The application of bioceramic hydroxyapatite (HA) derived
from materials high in calcium to tissue engineering has been of concern, namely
scaffold. Scaffold pores allow for cell mobility metabolic processes, and
delivery of oxygen and nutrients by blood vessel. Thus, pore architecture
affects cell seeding efficiency, cell viability, migration, morphology, cell
proliferation, c... hiện toàn bộ