Biomaterials Research
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Guided bone regeneration using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC)-cross-linked type-I collagen membrane with biphasic calcium phosphate at rabbit calvarial defects
Biomaterials Research - Tập 19 - Trang 1-10 - 2015
In-vitro and animal studies using EDC cross-linked membranes have shown great
resistance to enzymatic digestion as well as low cytotoxicity, and indicated its
potential expediency as a barrier membrane for guided bone regeneration (GBR).
The purpose of this study was to evaluate the efficacy, biocompatibility and
degradation kinetics of a novel 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide
(EDC)-...
Recent advances in stem cell therapeutics and tissue engineering strategies
Biomaterials Research - Tập 22 - Trang 1-8 - 2018
Tissue regeneration includes delivering specific types of cells or cell products
to injured tissues or organs for restoration of tissue and organ function. Stem
cell therapy has drawn considerable attention since transplantation of stem
cells can overcome the limitations of autologous transplantation of patient’s
tissues; however, it is not perfect for treating diseases. To overcome the
hurdles as...
Confocal imaging of biomarkers at a single-cell resolution: quantifying 'living' in 3D-printable engineered living material based on Pluronic F-127 and yeast Saccharomyces cerevisiae
Biomaterials Research - Tập 26 - Trang 1-15 - 2022
Engineered living materials (ELMs) combine living cells with non-living
scaffolds to obtain life-like characteristics, such as biosensing, growth, and
self-repair. Some ELMs can be 3D-printed and are called bioinks, and their
scaffolds are mostly hydrogel-based. One such scaffold is polymer Pluronic F127,
a liquid at 4 °C but a biocompatible hydrogel at room temperature. In such
thermally-reversib...
Review of bone graft and bone substitutes with an emphasis on fracture surgeries
Biomaterials Research - Tập 23 - Trang 1-7 - 2019
Autogenous bone graft is the gold standard bone graft material. However, due to
limitations of supply and morbidity associated with autograft harvest, various
bone substitutes have been considered. This article aims to review the
properties of the bone graft and various bone substitutes currently available in
orthopedic surgery. Synthetic bone substitutes consist of hydroxyapatite,
tricalcium phos...
Impact of simultaneous placement of implant and block bone graft substitute: an in vivo peri-implant defect model
Biomaterials Research - Tập 25 - Trang 1-10 - 2021
Insufficient bone volume around an implant is a common obstacle when dental
implant treatment is considered. Limited vertical or horizontal bone dimensions
may lead to exposed implant threads following placement or a gap between the
bone and implant. This is often addressed by bone augmentation procedures prior
to or at the time of implant placement. This study evaluated bone healing when a
synthe...
In vitro photodynamic therapy of methylene blue-loaded acetyl resistant starch nanoparticles
Biomaterials Research - Tập 26 - Trang 1-12 - 2022
Combination therapies comprising multiple methods, such as photodynamic therapy
have been applied to be complements chemotherapy as they increase the
therapeutic efficiency by enabling the intelligent drug delivery to target sites
by exposing the photosensitizer to light and activating it in the tumor tissue.
This study evaluated in vitro photodynamic therapy of methylene blue (MB)-loaded
acetyl r...
GM-CSF augmented the photothermal immunotherapeutic outcome of self-driving gold nanoparticles against a mouse CT-26 colon tumor model
Biomaterials Research - Tập 27 - Trang 1-17 - 2023
Hypoxia is a frequent characteristic observed in solid tumors and is strongly
associated with tumor metastasis, angiogenesis, and drug resistance. While the
vasculature of hypoxic tumor tissues poses obstacles to the efficient
administration of conventional drugs, it may prove advantageous in sustaining
hyperthermia. Photothermal therapy (PTT) offers a promising treatment strategy
that utilizes th...
Effect of alginate concentration on chondrogenesis of co-cultured human adipose-derived stem cells and nasal chondrocytes: a biological study
Biomaterials Research - Tập 21 - Trang 1-11 - 2017
The three-dimensional (3D) system is one of the important factors to engineer a
biocompatible and functional scaffold for the applications of cell-based
therapies for cartilage repair. The 3D alginate hydrogels system has previously
been shown to potentially promote chondrogenesis. The chondrocytic
differentiation of co-cultured adipose-derived stem cells (ADSCs) and nasal
chondrocytes (NCs) withi...
Schwann cell durotaxis can be guided by physiologically relevant stiffness gradients
Biomaterials Research - Tập 22 Số 1 - 2018
Abstract Background Successful nerve regeneration depends upon directed
migration of morphologically specialized repair state Schwann cells across a
nerve defect. Although several groups have studied directed migration of Schwann
cells in response to chemical or topographic cues, the current understanding of
how the mechanical environment influences migration remains largely understudied
and incom...
Natural bone-mimicking nanopore-incorporated hydroxyapatite scaffolds for enhanced bone tissue regeneration
Biomaterials Research - - 2022
Abstract Background A considerable number of studies has been carried out to
develop alloplastic bone graft materials such as hydroxyapatite (HAP) that mimic
the hierarchical structure of natural bones with multiple levels of pores:
macro-, micro-, and nanopores. Although nanopores are known to play many
essential roles in natural bones, only a few studies have focused on HAPs
containing them; non...
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