Biomaterials Research

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In vitro photodynamic therapy of methylene blue-loaded acetyl resistant starch nanoparticles
Biomaterials Research - Tập 26 - Trang 1-12 - 2022
In-Kyu Park, Do-Bin Ju, Amal Babu, Jeong-Cheol Lee, Young Jin Pyung, Chong-Su Cho, Hyun-Joong Kim
Combination therapies comprising multiple methods, such as photodynamic therapy have been applied to be complements chemotherapy as they increase the therapeutic efficiency by enabling the intelligent drug delivery to target sites by exposing the photosensitizer to light and activating it in the tumor tissue. This study evaluated in vitro photodynamic therapy of methylene blue (MB)-loaded acetyl r...... hiện toàn bộ
Coacervate-mediated novel pancreatic cancer drug Aleuria Aurantia lectin delivery for augmented anticancer therapy
Biomaterials Research - Tập 26 - Trang 1-12 - 2022
Sungjun Kim, Yunyoung Choi, Kyobum Kim
Pancreatic cancer, one of the cancers with the highest mortality rate, has very limited clinical treatment. Cancer cells express abnormal glycans on the surface, and some lectins with a high affinity for the glycans induce apoptosis in cancer. In this study, the efficacy of Aleuria Aurantia lectin (AAL) for the treatment of pancreatic cancer was evaluated and the efficacy improvement through AAL d...... hiện toàn bộ
Correction: High-glutathione mesenchymal stem cells isolated using the FreSHtracer probe enhance cartilage regeneration in a rabbit chondral defect model
Biomaterials Research - Tập 27 - Trang 1-1 - 2023
Gun Hee Cho, Hyun Cheol Bae, Won Young Cho, Eui Man Jeong, Hee Jung Park, Ha Ru Yang, Sun Young Wang, You Jung Kim, Dong Myung Shin, Hyung Min Chung, In Gyu Kim, Hyuk-Soo Han
Correlation between two-dimensional micro-CT and histomorphometry for assessment of the implant osseointegration in rabbit tibia model
Biomaterials Research - - 2021
Hao Lyu, Jae Hyup Lee
Abstract Background Histology is considered as a gold standard for analyzing bone architecture. However, histomorphometry is a destructive method and only offers the bone information of a limited location. Micro-computed tomography (μCT) is a non-destructive technology and provides a slice at any...... hiện toàn bộ
MG-63 osteoblast-like cell proliferation on auxetic PLGA scaffold with mechanical stimulation for bone tissue regeneration
Biomaterials Research - Tập 20 - Trang 1-8 - 2016
Hong Jin Choi, Jun Jae Lee, Yeong Jun Park, Jung-Woog Shin, Hak-Joon Sung, Ji Won Shin, Yanru Wu, Jeong Koo Kim
Auxetic scaffolds (experimental) was fabricated by using poly(D, L-lactic-co-glycolic acid), 50:50, (PLGA) for effective bone cell proliferation with mechanical stimulation. Negative Poisson’s ratio in scaffold, 3-directional volumetric compression was applied during the scaffold fabrication at adequate temperature (60 °C). The pore size of scaffold ranged between 355 and 400 μm. The porous morpho...... hiện toàn bộ
Guided bone regeneration using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC)-cross-linked type-I collagen membrane with biphasic calcium phosphate at rabbit calvarial defects
Biomaterials Research - Tập 19 - Trang 1-10 - 2015
Jin-Young Park, Im-Hee Jung, You-Kyoung Kim, Hyun-Chang Lim, Jung-Seok Lee, Ui-Won Jung, Seong-Ho Choi
In-vitro and animal studies using EDC cross-linked membranes have shown great resistance to enzymatic digestion as well as low cytotoxicity, and indicated its potential expediency as a barrier membrane for guided bone regeneration (GBR). The purpose of this study was to evaluate the efficacy, biocompatibility and degradation kinetics of a novel 1-ethyl-3-(3-dimethylaminopropyl) ...... hiện toàn bộ
Recent advances in stem cell therapeutics and tissue engineering strategies
Biomaterials Research - Tập 22 - Trang 1-8 - 2018
Seong Gyu Kwon, Yang Woo Kwon, Tae Wook Lee, Gyu Tae Park, Jae Ho Kim
Tissue regeneration includes delivering specific types of cells or cell products to injured tissues or organs for restoration of tissue and organ function. Stem cell therapy has drawn considerable attention since transplantation of stem cells can overcome the limitations of autologous transplantation of patient’s tissues; however, it is not perfect for treating diseases. To overcome the hurdles as...... hiện toàn bộ
Confocal imaging of biomarkers at a single-cell resolution: quantifying 'living' in 3D-printable engineered living material based on Pluronic F-127 and yeast Saccharomyces cerevisiae
Biomaterials Research - Tập 26 - Trang 1-15 - 2022
Bojan Žunar, Taiga Ito, Christine Mosrin, Yoshiyuki Sugahara, Hélène Bénédetti, Régis Guégan, Béatrice Vallée
Engineered living materials (ELMs) combine living cells with non-living scaffolds to obtain life-like characteristics, such as biosensing, growth, and self-repair. Some ELMs can be 3D-printed and are called bioinks, and their scaffolds are mostly hydrogel-based. One such scaffold is polymer Pluronic F127, a liquid at 4 °C but a biocompatible hydrogel at room temperature. In such thermally-reversib...... hiện toàn bộ
Review of bone graft and bone substitutes with an emphasis on fracture surgeries
Biomaterials Research - Tập 23 - Trang 1-7 - 2019
Hoon-Sang Sohn, Jong-Keon Oh
Autogenous bone graft is the gold standard bone graft material. However, due to limitations of supply and morbidity associated with autograft harvest, various bone substitutes have been considered. This article aims to review the properties of the bone graft and various bone substitutes currently available in orthopedic surgery. Synthetic bone substitutes consist of hydroxyapatite, tricalcium phos...... hiện toàn bộ
Impact of simultaneous placement of implant and block bone graft substitute: an in vivo peri-implant defect model
Biomaterials Research - Tập 25 - Trang 1-10 - 2021
Minh Khai Le Thieu, Amin Homayouni, Lena Ringsby Hæren, Hanna Tiainen, Anders Verket, Jan Eirik Ellingsen, Hans Jacob Rønold, Johan Caspar Wohlfahrt, Antonio Gonzalez Cantalapiedra, Fernando Maria Guzon Muñoz, Maria Permuy Mendaña, Ståle Petter Lyngstadaas, Håvard Jostein Haugen
Insufficient bone volume around an implant is a common obstacle when dental implant treatment is considered. Limited vertical or horizontal bone dimensions may lead to exposed implant threads following placement or a gap between the bone and implant. This is often addressed by bone augmentation procedures prior to or at the time of implant placement. This study evaluated bone healing when a synthe...... hiện toàn bộ
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