Surface texture evaluation of additively manufactured metallic cellular scaffolds for acetabular implants using X-ray computed tomographyBio-Design and Manufacturing - Tập 2 - Trang 55-64 - 2019
Shan Lou, Luca Pagani, Wenhan Zeng, Muhammad U. Ghori, Xiangqian Jiang, Paul J. Scott
The surface topography of acetabular implants plays a key role in providing cell attachment and proliferation. The measurement and characterisation of the surface texture of the cellular scaffold layer on the acetabular cup are very difficult due to the 3D nature of scaffold geometry. It is proposed to use X-ray computed tomography (XCT) to measure the surface texture of an electron beam melting-p...... hiện toàn bộ
A state-of-the-art review of the fabrication and characteristics of titanium and its alloys for biomedical applicationsBio-Design and Manufacturing - Tập 5 - Trang 371-395 - 2021
Masoud Sarraf, Erfan Rezvani Ghomi, Saeid Alipour, Seeram Ramakrishna, Nazatul Liana Sukiman
Commercially pure titanium and titanium alloys have been among the most commonly used materials for biomedical applications since the 1950s. Due to the excellent mechanical tribological properties, corrosion resistance, biocompatibility, and antibacterial properties of titanium, it is getting much attention as a biomaterial for implants. Furthermore, titanium promotes osseointegration without any ...... hiện toàn bộ
Recent advances in chemically defined and tunable hydrogel platforms for organoid cultureBio-Design and Manufacturing - Tập 4 - Trang 641-674 - 2021
Tarun Agarwal, Nehar Celikkin, Marco Costantini, Tapas K. Maiti, Pooyan Makvandi
Recent developments in organoid culture technologies have made it possible to closely recapitulate intrinsic characteristics of different tissues under in vitro conditions. These organoids act as a translational bridge between the traditional 2D/3D cultures and the in vivo models for studying the tissue development processes, disease modeling, and drug screening. Matrigel and tissue-specific extra...... hiện toàn bộ
Evaluation of L929 cell morphology on anthocyanin-containing gelatin-based hydrogel for early detection of infectionBio-Design and Manufacturing - Tập 2 - Trang 181-186 - 2019
Ghazal Shineh, Soheila S. Kordestani, Mohammadreza Tahriri, Lobat Tayebi
Wounds heal through a complex process including four phases. Any interruption or interference in healing process can prevent wound healing. Infection is one of the most common complications preventing wounds from healing. In this study, we investigated the fibroblast cell morphology and behavior of a gelatin-based hydrogel containing anthocyanin to determine whether it can be used for early detect...... hiện toàn bộ
Accelerated fracture healing by osteogenic Ti45Nb implants through the PI3K–Akt signaling pathwayBio-Design and Manufacturing - Tập 6 - Trang 718-734 - 2023
Jia Tan, Jiaxin Li, Zhaoyang Ran, Junxiang Wu, Dinghao Luo, Bojun Cao, Liang Deng, Xiaoping Li, Wenbo Jiang, Kai Xie, Lei Wang, Yongqiang Hao
The key to managing fracture is to achieve stable internal fixation, and currently, biologically and mechanically appropriate internal fixation devices are urgently needed. With excellent biocompatibility and corrosion resistance, titanium–niobium alloys have the potential to become a new generation of internal fixation materials for fractures. However, the role and mechanism of titanium–niobium a...... hiện toàn bộ
Bioinspired flexible piezoresistive sensor for high-sensitivity detection of broad pressure rangeBio-Design and Manufacturing - Tập 6 - Trang 243-254 - 2022
Meng Wang, Hao Zhang, Han Wu, Suqian Ma, Lei Ren, Yunhong Liang, Chunbao Liu, Zhiwu Han
The human skin has the ability to sense tactile touch and a great range of pressures. Therefore, in prosthetic or robotic systems, it is necessary to prepare pressure sensors with high sensitivity in a wide measurement range to provide human-like tactile sensation. Herein, we developed a flexible piezoresistive pressure sensor that is highly sensitive in a broad pressure range by using lotus leaf ...... hiện toàn bộ
3D bioprinted hyaluronic acid-based cell-laden scaffold for brain microenvironment simulationBio-Design and Manufacturing - - 2020
Liang Ma, Yuting Li, Yutong Wu, Mengfei Yu, Abdellah Aazmi, Lei Gao, Qian Xue, Yichen Luo, Hongzhao Zhou, Bin Zhang, Huayong Yang
Treatments for lesions in central nervous system (CNS) are always faced with challenges due to the anatomical and physiological particularity of the CNS despite the fact that several achievements have been made in early diagnosis and precision medicine to improve the survival and quality of life of patients with brain tumors in recent years. Understanding the complexity as well as role of the micr...... hiện toàn bộ
Bioprinting of novel 3D tumor array chip for drug screeningBio-Design and Manufacturing - Tập 3 - Trang 175-188 - 2020
Mingjun Xie, Qing Gao, Jianzhong Fu, Zichen Chen, Yong He
Biomedical field has been seeking a feasible standard drug screening system consisting of 3D tumor model array for drug researching due to providing sufficient samples and simulating actual in vivo tumor growth situation, which is still a challenge to rapidly and uniformly establish though. Here, we propose a novel drug screening system, namely 3D tumor array chip with “layer cake” structure, for ...... hiện toàn bộ