Springer Science and Business Media LLC
1471-2148
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Evolution, substrate specificity and subfamily classification of glycoside hydrolase family 5 (GH5)Abstract
Background
The large Glycoside Hydrolase family 5 (GH5) groups together a wide range of enzymes acting on β-linked oligo- and polysaccharides, and glycoconjugates from a large spectrum of organisms. The long and complex evolution of this family of enzymes and its broad sequence diversity... ...
Tập 12 Số 1 - 2012
Insights on the evolution of trehalose biosynthesisAbstract
Background
The compatible solute trehalose is a non-reducing disaccharide, which accumulates upon heat, cold or osmotic stress. It was commonly accepted that trehalose is only present in extremophiles or cryptobiotic organisms. However, in recent years it has been shown that although hig... ...
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The origin of multicellularity in cyanobacteria
Tập 11 - Trang 1-21 - 2011
Cyanobacteria are one of the oldest and morphologically most diverse prokaryotic phyla on our planet. The early development of an oxygen-containing atmosphere approximately 2.45 - 2.22 billion years ago is attributed to the photosynthetic activity of cyanobacteria. Furthermore, they are one of the few prokaryotic phyla where multicellularity has evolved. Understanding when and how multicellularity......
A phylogeny and molecular barcodes for Caenorhabditis, with numerous new species from rotting fruits
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Molecular evolution of the reactive oxygen-generating NADPH oxidase (Nox/Duox) family of enzymesAbstract Background NADPH-oxidases (Nox) and the related Dual oxidases (Duox) play varied biological and pathological roles via regulated generation of reactive oxygen species (ROS). Members of the Nox/Duox family have been identified in a wide variety of organisms, including mammals, nematodes, fruit fly, green plants, fungi, and s...
Tập 7 Số 1 - 2007
Codon usage bias and the evolution of influenza A viruses. Codon Usage Biases of Influenza VirusAbstract
Background
The influenza A virus is an important infectious cause of morbidity and mortality in humans and was responsible for 3 pandemics in the 20th century. As the replication of the influenza virus is based on its host's machinery, codon usage of its viral genes ... ...
Tập 10 Số 1 - 2010
Is autoinducer-2 a universal signal for interspecies communication: a comparative genomic and phylogenetic analysis of the synthesis and signal transduction pathwaysAbstract
Background
Quorum sensing is a process of bacterial cell-to-cell communication involving the production and detection of extracellular signaling molecules called autoinducers. Recently, it has been proposed that autoinducer-2 (AI-2), a furanosyl borate diester derived from t... ...
Tập 4 Số 1