Henrik Aspeborg, Pedro M. Coutinho, Yang Wang, Harry Brumer, Bernard Henrissat
Abstract Background The large Glycoside Hydrolase family 5 (GH5) groups together
a wide range of enzymes acting on β-linked oligo- and polysaccharides, and
glycoconjugates from a large spectrum of organisms. The long and complex
evolution of this family of enzymes and its broad sequence diversity limits
functional prediction. With the objective of improving the differentiation of
enzyme specificit... hiện toàn bộ
Nelson Avonce, Alfredo Mendoza-Vargas, Enrique Morett, Gabriel Iturriaga
Abstract Background The compatible solute trehalose is a non-reducing
disaccharide, which accumulates upon heat, cold or osmotic stress. It was
commonly accepted that trehalose is only present in extremophiles or
cryptobiotic organisms. However, in recent years it has been shown that although
higher plants do not accumulate trehalose at significant levels they have
actively transcribed genes encod... hiện toàn bộ
AbstractBackgroundNADPH-oxidases (Nox) and the related Dual oxidases (Duox) play
varied biological and pathological roles via regulated generation of reactive
oxygen species (ROS). Members of the Nox/Duox family have been identified in a
wide variety of organisms, including mammals, nematodes, fruit fly, green
plants, fungi, and slime molds; however, little is known about the molecular
evolutionar... hiện toàn bộ
Emily Hoi-Man Wong, David K. Smith, Raúl Rabadán, Malik Peiris, Leo L. M. Poon
Abstract Background The influenza A virus is an important infectious cause of
morbidity and mortality in humans and was responsible for 3 pandemics in the
20th century. As the replication of the influenza virus is based on its host's
machinery, codon usage of its viral genes might be subject to host selection
pressures, especially after interspecies transmission. A better understanding of
viral ev... hiện toàn bộ
Abstract Background Quorum sensing is a process of bacterial cell-to-cell
communication involving the production and detection of extracellular signaling
molecules called autoinducers. Recently, it has been proposed that autoinducer-2
(AI-2), a furanosyl borate diester derived from the recycling of
S-adenosyl-homocysteine (SAH) to homocysteine, serves as a universal signal for
interspecies communi... hiện toàn bộ
Robert K. Jansen, Charalambos Kaittanis, Christopher Saski, Seung Bum Lee, Jeffrey Tomkins, Andrew J. Alverson, Henry Daniell
AbstractBackgroundThe Vitaceae (grape) is an economically important family of
angiosperms whose phylogenetic placement is currently unresolved. Recent
phylogenetic analyses based on one to several genes have suggested several
alternative placements of this family, including sister to Caryophyllales,
asterids, Saxifragales, Dilleniaceae or to rest of rosids, though support for
these different resul... hiện toàn bộ