SAGE Publications
SCOPUS (1990-2004)
1045-4411
1544-1113
Cơ quản chủ quản: N/A
Các bài báo tiêu biểu
Matrix Metalloproteinases: A Review
Tập 4 Số 2 - Trang 197-250 - 1993
Matrix metalloproteinases (MMPs) are a family of nine or more highly homologous
Zn++endopeptidases that collectively cleave most if not all of the constituents
of the extracellular matrix. The present review discusses in detail the primary
structures and the overlapping yet distinct substrate specificities of MMPs as
well as the mode of activation of the unique MMP precursors. The regulation of
MM...
Oral Sequelae of Head and Neck Radiotherapy
Tập 14 Số 3 - Trang 199-212 - 2003
In addition to anti-tumor effects, ionizing radiation causes damage in normal
tissues located in the radiation portals. Oral complications of radiotherapy in
the head and neck region are the result of the deleterious effects of radiation
on, e.g., salivary glands, oral mucosa, bone, dentition, masticatory
musculature, and temporomandibular joints. The clinical consequences of
radiotherapy include ...
The Pathogenesis of Oral Lichen Planus
Tập 13 Số 4 - Trang 350-365 - 2002
Both antigen-specific and non-specific mechanisms may be involved in the
pathogenesis of oral lichen planus (OLP). Antigen-specific mechanisms in OLP
include antigen presentation by basal keratinocytes and antigen-specific
keratinocyte killing by CD8+ cytotoxic T-cells. Non-specific mechanisms include
mast cell degranulation and matrix metalloproteinase (MMP) activation in OLP
lesions. These mecha...
Acute and Chronic Craniofacial Pain: Brainstem Mechanisms of Nociceptive Transmission and Neuroplasticity, and Their Clinical Correlates
Tập 11 Số 1 - Trang 57-91 - 2000
This paper reviews the recent advances in knowledge of brainstem mechanisms
related to craniofacial pain. It also draws attention to their clinical
implications, and concludes with a brief overview and suggestions for future
research directions. It first describes the general organizational features of
the trigeminal brainstem sensory nuclear complex (VBSNC), including its input
and output propert...
Update On Oral Lichen Planus: Etiopathogenesis and Management
Tập 9 Số 1 - Trang 86-122 - 1998
Lichen planus (LP) is a relatively common disorder of the stratified squamous
epithelia, which is, in many ways, an enigma. This paper is the consensus
outcome of a workshop held in Switzerland in 1995, involving a selection of
clinicians and scientists with an interest in the condition and its management.
The oral (OLP) eruptions usually have a distinct clinical morphology and
characteristic dist...
Tetracyclines Inhibit Connective Tissue Breakdown: New Therapeutic Implications for an Old Family of Drugs
Tập 2 Số 3 - Trang 297-321 - 1991
Tetracyclines have long been considered useful adjuncts in peridontal therapy
based on their antimicrobial efficacy against putative periodontopathogens.
However, recently these drugs were found to inhibit mammalian collagenases and
several other matrix metalloproteinases (MMPs) by a mechanism independent of
their antimicrobial activity. Evidence is presented that this property may be
therapeutica...
Neurobiological Mechanisms Involved in Sleep Bruxism
Tập 14 Số 1 - Trang 30-46 - 2003
Sleep bruxism (SB) is reported by 8% of the adult population and is mainly
associated with rhythmic masticatory muscle activity (RMMA) characterized by
repetitive jaw muscle contractions (3 bursts or more at a frequency of 1 Hz).
The consequences of SB may include tooth destruction, jaw pain, headaches, or
the limitation of mandibular movement, as well as tooth-grinding sounds that
disrupt the sle...
Relation of Dental Composite Formulations To Their Degradation and the Release of Hydrolyzed Polymeric-Resin-Derived Products
Tập 12 Số 2 - Trang 136-151 - 2001
This article reviews the principal modes of dental composite material
degradation and relates them to the specific components of the composites
themselves. Particular emphasis is placed on the selection of the monomer
resins, the filler content, and the degree of monomer conversion after the
clinical materials are cured. Loss of mechanical function and leaching of
components from the composites ar...
Interaction of Plant Polyphenols with Salivary Proteins
Tập 13 Số 2 - Trang 184-196 - 2002
Tannins are polyphenols that occur widespread in plant-based food. They are
considered to be part of the plant defense system against environmental
stressors. Tannins have a number of effects on animals, including growth-rate
depression and inhibition of digestive enzymes. Tannins also have an effect on
humans: They are, for example, the cause of byssinosis, a condition that is due
to exposure to ...
Dental Fluorosis : Chemistry and Biology
Tập 13 Số 2 - Trang 155-170 - 2002
This review aims at discussing the pathogenesis of enamel fluorosis in relation
to a putative linkage among ameloblastic activities, secreted enamel matrix
proteins and multiple proteases, growing enamel crystals, and fluid composition,
including calcium and fluoride ions. Fluoride is the most important
caries-preventive agent in dentistry. In the last two decades, increasing
fluoride exposure in ...