SAGE Publications
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Hydroxyapatite Binding Domains in Salivary Proteins
SAGE Publications - Tập 4 Số 3 - Trang 371-378 - 1993
Salivary α-Amylase: Role in Dental Plaque and Caries Formation
SAGE Publications - Tập 4 Số 3 - Trang 301-307 - 1993
Salivary α-amylase, one of the most plentiful components in human saliva, has at
least three distinct biological functions. The enzymatic activity of a-amylase
undoubtedly plays a role in carbohydrate digestion. Amylase in solution binds
with high affinity to a selected group of oral streptococci, a function that may
contribute to bacterial clearance and nutrition. The fact that a-amylase is also
...
Saliva-Bacterium Interactions in Oral Microbial Ecology
SAGE Publications - Tập 5 Số 3 - Trang 203-248 - 1994
Saliva is thought to have a significant impact on the colonization of
microorganisms in the oral cavity. Salivary components may participate in this
process by one of four general mechanisms: binding to microorganisms to
facilitate their clearance from the oral cavity, serving as receptors in oral
pellicles for microbial adhesion to host surfaces, inhibiting microbial growth
or mediating microbial...
Structural Characteristics of Human Salivary Statherin: A Model for Boundary Lubrication at the Enamel Surface
SAGE Publications - Tập 4 Số 3 - Trang 363-370 - 1993
A three-dimensional structural model for salivary statherin in aqueous phase has
been developed using structure prediction, circular dichroism, molecular
modeling, and mechanics. The relevant structural features of statherin are
N-terminal helix segment connected to a long poly-L-proline type II segment,
which is followed by a short extended structure. Using this model, the
hydroxyapatite binding ...
Oral Sequelae of Head and Neck Radiotherapy
SAGE Publications - Tập 14 Số 3 - Trang 199-212 - 2003
In addition to anti-tumor effects, ionizing radiation causes damage in normal
tissues located in the radiation portals. Oral complications of radiotherapy in
the head and neck region are the result of the deleterious effects of radiation
on, e.g., salivary glands, oral mucosa, bone, dentition, masticatory
musculature, and temporomandibular joints. The clinical consequences of
radiotherapy include ...
Acute and Chronic Craniofacial Pain: Brainstem Mechanisms of Nociceptive Transmission and Neuroplasticity, and Their Clinical Correlates
SAGE Publications - Tập 11 Số 1 - Trang 57-91 - 2000
This paper reviews the recent advances in knowledge of brainstem mechanisms
related to craniofacial pain. It also draws attention to their clinical
implications, and concludes with a brief overview and suggestions for future
research directions. It first describes the general organizational features of
the trigeminal brainstem sensory nuclear complex (VBSNC), including its input
and output propert...
Involvement of T-Lymphocytes in Periodontal Disease and in Direct and Indirect Induction of Bone Resorption
SAGE Publications - Tập 12 Số 2 - Trang 125-135 - 2001
Periodontal disease is a peripheral infection involving species of Gram-negative
organisms. T-lymphocytes can be found in the dense inflammatory infiltrate in
this disease. CD4+ and CD8+ T-cells are present in periodontal lesions, as are
memory/activated T-lymphocytes. In addition, Th1- and Th2-type T-lymphocytes and
their associated cytokines with a subtle polarization to Th 1 may be present.
Th1...
Update On Oral Lichen Planus: Etiopathogenesis and Management
SAGE Publications - Tập 9 Số 1 - Trang 86-122 - 1998
Lichen planus (LP) is a relatively common disorder of the stratified squamous
epithelia, which is, in many ways, an enigma. This paper is the consensus
outcome of a workshop held in Switzerland in 1995, involving a selection of
clinicians and scientists with an interest in the condition and its management.
The oral (OLP) eruptions usually have a distinct clinical morphology and
characteristic dist...
Interaction of Plant Polyphenols with Salivary Proteins
SAGE Publications - Tập 13 Số 2 - Trang 184-196 - 2002
Tannins are polyphenols that occur widespread in plant-based food. They are
considered to be part of the plant defense system against environmental
stressors. Tannins have a number of effects on animals, including growth-rate
depression and inhibition of digestive enzymes. Tannins also have an effect on
humans: They are, for example, the cause of byssinosis, a condition that is due
to exposure to ...
Dental Fluorosis : Chemistry and Biology
SAGE Publications - Tập 13 Số 2 - Trang 155-170 - 2002
This review aims at discussing the pathogenesis of enamel fluorosis in relation
to a putative linkage among ameloblastic activities, secreted enamel matrix
proteins and multiple proteases, growing enamel crystals, and fluid composition,
including calcium and fluoride ions. Fluoride is the most important
caries-preventive agent in dentistry. In the last two decades, increasing
fluoride exposure in ...
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