Psychopharmacology
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Sucrose intake by rats affected by both intraperitoneal oxytocin administration and time of day
Psychopharmacology - Tập 239 - Trang 429-442 - 2021
Daily limited access to palatable food or drink at a fixed time is commonly used in rodent models of bingeing. Under these conditions, entrainment may modulate intake patterns. Oxytocin is involved in circadian patterns of intake and, when administered peripherally, reduces sucrose intake. However, oxytocin’s effects on intake under limited-access conditions and its potential interaction with entr......
Differential effects of excitotoxic lesions of the amygdala on cocaine-induced conditioned locomotion and conditioned place preference
Psychopharmacology - Tập 113 - Trang 123-130 - 1993
The reinforcing properties of cocaine can readily become associated with salient environmental stimuli that acquire secondary reinforcing properties. This type of classical conditioning is of considerable clinical relevance, as intense drug craving can be evoked by the presentation of stimuli previously associated with the effects of cocaine. Given the large body of evidence that implicates the am......
Motivational effects of drugs: Methods which illustrate some general problems in psychopharmacology
Psychopharmacology - Tập 1 - Trang 169-199 - 1960
Neuropeptide systems and new treatments for nicotine addiction
Psychopharmacology - Tập 234 - Trang 1419-1437 - 2016
The mildly euphoric and cognitive enhancing effects of nicotine play a role in the initiation of smoking, while dysphoria and anxiety associated with smoking cessation contribute to relapse. After the acute withdrawal phase, smoking cues, a few cigarettes (i.e., lapse), and stressors can cause relapse. Human and animal studies have shown that neuropeptides play a critical role in nicotine addictio......
Dopamine D1 receptors mediate methamphetamine-induced dopaminergic damage: involvement of autophagy regulation via the AMPK/FOXO3A pathway
Psychopharmacology - - 2022
Delta-9-tetrahydrocannabinol enhances food reinforcement in a mouse operant conflict test
Psychopharmacology - Tập 205 - Trang 475-487 - 2009
Cannabinoid compounds are known to regulate feeding behavior by modulating the hedonic and/or the incentive properties of food. The aim of this work was to determine the involvement of the cannabinoid system in food reinforcement associated with a conflict situation generated by stress. Mice were trained on a fixed ratio 1 schedule of reinforcement to obtain standard, chocolate-flavored or fat-enr......
Effects of ritanserin and chlordiazepoxide on sleep-wakefulness alterations in rats following chronic cocaine treatment
Psychopharmacology - Tập 108 - Trang 263-270 - 1992
The effects of ritanserin, a 5-hydroxytryptamine-2 (5-HT2) receptor antagonist, and chlordiazepoxide, a benzodiazepine agonist, on sleep-wakefulness disturbances in rats after acute administration of cocaine and after discontinuation of chronic cocaine treatment were examined. Intraperitoneal (IP) injection of chlordiazepoxide (10 mg/kg) but not ritanserin (0.63 mg/kg) prevented the increase of wa......
Effects of tianeptine on the performance of a reaching movement in the cat
Psychopharmacology - Tập 104 - Trang 328-336 - 1991
Unlike other antidepressant drugs, tianeptine, when administered to cats at doses ranging from 1.2 to 5 mg/kg, produces an increase in arousal associated with longer sequences of immobile attentiveness. The present study analyses tianeptine-induced effects on visuomotor performance. Cats were trained to perform a pointing movement towards a randomly moving spot of light. Following tianeptine treat......
Cognitive impact of social stress and coping strategy throughout development
Psychopharmacology - Tập 232 - Trang 185-195 - 2014
Stress experience during adolescence has been linked to the development of psychiatric disorders in adulthood, many of which are associated with impairments in prefrontal cortex function. The current study was designed to determine the immediate and enduring effects of repeated social stress on a prefrontal cortex-dependent cognitive task. Early adolescent (P28), mid-adolescent (P42), and adult (P......
Different effects of isolation-rearing and neonatal MK-801 treatment on attentional modulations of prepulse inhibition of startle in rats
Psychopharmacology - Tập 233 Số 17 - Trang 3089-3102 - 2016
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