Motivational effects of drugs: Methods which illustrate some general problems in psychopharmacology

Bailey, C. J., and N. E. Miller: The effect of sodium amytal on an approach-avoidance conflict in cats. J. exp. Psychol. 45, 205–208 (1952). Barry, H. III: Effects of strength of drive on learning and on extinction. J. exp. Psychol. 55, 473–481 (1958). Beach, F. A., and A. M. Holz-Tucker: Effects of different concentrations of androgen upon sexual behavior in castrated male rats. J. comp. physiol. Psychol. 42, 433–453 (1949). — and L. Jordan: Effects of sexual reinforcement upon the performance of male rats in a straight runway. J. comp. physiol. Psychol. 49, 105–110 (1956). Berlyne, D. E.: Novelty and curiosity as determiners of exploratory behavior. Brit. J. Psychol. 41, 68–80 (1950). Black, A. H.: The extinction of avoidance responses under curare. J. comp. physiol. Psychol. 51, 519–524 (1958). Blough, D. S.: New test for tranquilizers. Science 127, 586–587 (1958). Brown, J. S.: Gradients of approach and avoidance responses and their relation to level of motivation. J. comp. physiol. Psychol. 41, 450–465 (1948). —, H. I. Kalish and I. E. Farber: Conditioned fear as revealed by magnitude of startle response to an auditory stimulus. J. exp. Psychol. 41, 317–328 (1951). Campbell, B. A., and D. Kraeling: Response strength as a function of drive level and amount of drive reduction. J. exp. Psychol. 45, 97–101 (1953). Conger, J. J.: The effects of alcohol on conflict behavior in the albino rat. Quart. J. Stud. Alcohol 12, 1–29 (1951). Dinsmoor, J. A.: A new shock grid for rats. J. exp. Anal. Behav. 1, 182 (1958). Dollard, J., and N. E. Miller: Personality and psychotherapy. New York: McGraw-Hill 1950. Estes, W. K., and B. F. Skinner: Some quantitative properties of anxiety. J. exp. Psychol. 29, 390–400 (1941). Ferster, C. B., and B. F. Skinner: Schedules of reinforcement. New York: Appleton-Century-Crofts 1957. Gantt, W. H.: Experimental basis for neurotic behavior; origin and development of artificially produced disturbances of behavior in dogs. New York: Paul B. Hoeber 1944. Hearst, E., and M. Sidman: Escape from a concurrently positive and negative stimulus. Paper read at meetings of the Eastern Psychological Association, April, 1959. Hervey, C. R.: The effects of lesions in the hypothalamus in parabiotic rats. J. Physiol. (Lond.) 145, 336–352 (1957). Hess, E. H.: Effects of meprobamate on imprinting in waterfowl. Ann. N.Y. Acad. Sci. 67, 724–732 (1957). Hill, J. H., and E. Stellar: An electric drinkometer. Science 114, 43–44 (1951). Hull, C. L.: The rat's speed-of-locomotion gradient in the approach to food. J. comp. Psychol. 17, 393–422 (1934). Hunt, H. F.: Some effects of emotional reponses and abnormal behavior in animals. Conference on Drugs in Psychiatry, National Research Council 1956. Jenkins, T. N., L. H. Warner and C. J. Warden: Standard apparatus for the study of animal motivation. J. comp. Psychol. 6, 361–382 (1926). Lacey, J. I., and R. van Lehn: Differential emphasis in somatic response to stress. Psychosom. Med. 14, 71–81 (1952). Levine, S.: Noxious stimulation in infant and adult rats and consummatory behavior. J. comp. physiol. Psychol. 51, 230–233 (1958). —, and G. W. Lewis: The relative importance of experimenter contact in an effect produced by extra-stimulation in infancy. J. comp. physiol. Psychol. 52, 368–369 (1959). Lilly, J. C.: Development of a double-table-chair method of restraining monkeys for physiological and psychological research. J. Applied Physiol. 12, 134–136 (1958). Lindsley, D. B.: Emotion. In S. S. Stevens' Handbook of experimental psychology, p. 473–516. New York: Wiley 1951. Logan, F. A.: Incentive: How the conditions of reinforcement affect the performance of rats. New Haven: Yale University Press 1960. Mason, J. W. and J. V. Brady: Plasma 17-hydroxycorticosteroid changes related to reserpine effects on emotional behavior. Science 124, 983–984 (1955). Masserman, J. H., and K. S. Yum: An analysis of the influence of alcohol on experimental neurosis in cats. Psychosom. Med. 8, 36–52 (1946). Miller, N. E.: Outline on training and habituation of rats for laboratory work. In R. W. Gerard, Methods in medical research, vol. III, p. 216–218. New York: Year Book Publ. 1950. —: Learnable drives and rewards. In S. S. Stevens' Handbook of experimental psychology, p. 435–472. New York: Wiley 1951. —: Effects of drugs on motivation: the value of using a variety of measures. Ann. N.Y. Acad. Sci. 65, 318–333 (1956). —: A psychologist speaks. In H. D. Kruse, Integrating the approaches to mental disease, p. 43–45. New York: Paul B. Hoeber 1957a. —: Objective techniques for studying motivational effects of drugs on animals. In S. Garattini and V. Ghetti, Psychotropic drugs, p. 83–103. Amsterdam: Elsevier 1957b. —: Experiments on motivation: studies combining psychological, physiological, and pharmacological techniques. Science 126, 1271–1278 (1957c). —: Liberalization of basic S-R concepts: Extensions to conflict behavior, motivation, and social learning. In S. Koch, A study of a science, Study 1, vol. 2, p. 196–292. New York: McGraw-Hill 1959. —, C. J. Bailey and J. A. F. Stevenson: Decreased “hunger” but increased food intake resulting from hypothalamic lesions. Science 112, 256–259 (1950). — and D. Kraeling: Displacement: greater generalization of approach than avoidance in a generalized approach-avoidance conflict. J. exp. Psychol. 43, 217–221 (1952). —, and W. R. Miles: Effect of caffeine on the running speed of hungry, satiated, and frustrated rats. J. comp. Psychol. 20, 397–412 (1935). —: Alcohol and removal of reward. An analytical study of rodent maze behavior. J. comp. Psychol. 21, 179–204 (1936). —: and E. J. Murray: Displacement and conflict: learnable drive as a basis for the steeper gradient of avoidance than of approach. J. exp. Psychol. 43, 227 to 231 (1952). Murray, E. J., and N. E. Miller: Displacement: steeper gradient of generalization of avoidance than of approach with age of habit controlled. J. exp. Psychol. 43, 222–226 (1952). Myers, A. K.: Avoidance learning as a function of several training conditions and strain differences in rats. J. comp. physiol. Psychol. 52, 381–386 (1959). — and N. E. Miller: Failure to find a learned drive based on hunger; evidence for learning motivated by “exploration”. J. comp. physiol. Psychol. 47, 428–436 (1954). Norton, S.: Behavioral patterns as a technique for studying psychotropic drugs. In S. Garattini and V. Ghetti, Psychotropic drugs, p. 73–82. Amsterdam: Elsevier 1957. Nowlis, V., and H. H. Nowlis: The description and analysis of mood. Ann. N.Y. Acad. Sci. 65, 345–355 (1956). Pavlov, I. P.: Conditioned reflexes. G. V. Anrep. (Trans.) London: Oxford University Press 1927. Ruegamer, W. R., L. Bernstein and J. D. Benjamin: Growth, food utilization, and thyroid activity in the albino rat as a function of extra handling. Science 120, 184–185 (1954). Sawrey, W. L., J. J. Conger and E. S. Turrell: An experimental investigation of the role of psychological factors in the production of gastric ulcers in rats. J. comp. physiol. Psychol. 49, 457–461 (1956). Schwartz, M.: Instrumental and consummatory measures of sexual capacity in the male rat. J. comp. physiol. Psychol. 49, 328–333 (1956). Sheffield, F. D., J. J. Wulff and R. Backer: Reward value of copulation without sex drive reduction. J. comp. physiol. Psychol. 44, 3–8 (1951). Sidman, M.: Avoidance conditioning with brief shock and no exteroceptive warning signal. Science 118, 157–158 (1953). —: Behavioral pharmacology. Psychopharmacologia 1, 1–19 (1959). Skinner, B. F.: The behavior of organisms. New York: Appleton-Century-Crofts 1938. Solomon, R. L. and E. S. Brush: Experimentally defined conceptions of anxiety and aversion. In M. R. Jones, Nebraska Symposium on Motivation, p. 212–305. Lincoln: University Nebraska Press 1956. Thorndike, E. L.: Animal intelligence. New York: Macmillan 1911. Walker, A. (edit.): A laboratory for the study of man. Ten year report of the Human Relations Area Files, Inc., 421 Humphrey Street, New Haven, Conn. 1959. Weiss, B., and M. B. Danford: Reward value of heat at low temperatures during inanition and panothenic acid deprivation. School of Aviation Medicine USAF Randolph AFB, Texas, Report No 56-72, 1956. Wenger, M. A.: Studies of autonomic balance in Army Air Force personnel. Comp. psychol. Monogr. Vol. 19, No 4. Berkeley: University Calif. Press 1948. Wikler, A.: The relation of psychiatry to pharmacology. Baltimore, Md.: Williams & Wilkins 1958. Wittenborn, J. R.: Symptom patterns in a group of mental hospital patients. J. cons. Psychol. 15, 290–302 (1951). Young, P. T.: Motivation of animal behavior. In C. P. Stone, Comparative Psychology, 3rd edit., p. 62–109. New York: Prentice-Hall 1951. Zimbardo, P. G., and N. E. Miller: Facilitation of exploration by hunger in rats. J. comp. physiol. Psychol. 51, 43–46 (1958).