Pharmaceutics

SCOPUS (2009-2023)SCIE-ISI

  1999-4923

 

  Thụy Sĩ

Cơ quản chủ quản:  MDPI , Multidisciplinary Digital Publishing Institute (MDPI)

Lĩnh vực:
Pharmaceutical Science

Các bài báo tiêu biểu

Liposomal Formulations in Clinical Use: An Updated Review
Tập 9 Số 2 - Trang 12
Upendra Bulbake, Sindhu Doppalapudi, Nagavendra Kommineni, Wahid Khan
Liposomes are the first nano drug delivery systems that have been successfully translated into real-time clinical applications. These closed bilayer phospholipid vesicles have witnessed many technical advances in recent years since their first development in 1965. Delivery of therapeutics by liposomes alters their biodistribution profile, which further enhances the therapeutic index of var...... hiện toàn bộ
An Overview of Chitosan Nanoparticles and Its Application in Non-Parenteral Drug Delivery
Tập 9 Số 4 - Trang 53
M. Mohammed, Jaweria Syeda, Kishor M. Wasan, Ellen K. Wasan
The focus of this review is to provide an overview of the chitosan based nanoparticles for various non-parenteral applications and also to put a spotlight on current research including sustained release and mucoadhesive chitosan dosage forms. Chitosan is a biodegradable, biocompatible polymer regarded as safe for human dietary use and approved for wound dressing applications. Chitosan has ...... hiện toàn bộ
Transdermal Drug Delivery: Innovative Pharmaceutical Developments Based on Disruption of the Barrier Properties of the Stratum Corneum
Tập 7 Số 4 - Trang 438-470
Ahlam Zaid Alkilani, Maelíosa McCrudden, Ryan F. Donnelly
The skin offers an accessible and convenient site for the administration of medications. To this end, the field of transdermal drug delivery, aimed at developing safe and efficacious means of delivering medications across the skin, has in the past and continues to garner much time and investment with the continuous advancement of new and innovative approaches. This review details the progr...... hiện toàn bộ
Skin Wound Healing Process and New Emerging Technologies for Skin Wound Care and Regeneration
Tập 12 Số 8 - Trang 735
Erika Maria Tottoli, Rossella Dorati, Ida Genta, Enrica Chiesa, Silvia Pisani, Bice Conti
Skin wound healing shows an extraordinary cellular function mechanism, unique in nature and involving the interaction of several cells, growth factors and cytokines. Physiological wound healing restores tissue integrity, but in many cases the process is limited to wound repair. Ongoing studies aim to obtain more effective wound therapies with the intention of reducing inpatient costs, prov...... hiện toàn bộ
Challenges and Recent Progress in Oral Drug Delivery Systems for Biopharmaceuticals
Tập 11 Số 3 - Trang 129
Bahman Homayun, Xueting Lin, Hyo‐Jick Choi
Routes of drug administration and the corresponding physicochemical characteristics of a given route play significant roles in therapeutic efficacy and short term/long term biological effects. Each delivery method has favorable aspects and limitations, each requiring a specific delivery vehicles design. Among various routes, oral delivery has been recognized as the most attractive method, ...... hiện toàn bộ
Protein-Based Nanoparticles as Drug Delivery Systems
Tập 12 Số 7 - Trang 604
Seyoung Hong, Dong Wook Choi, Hong Nam Kim, Chun Gwon Park, Wonhwa Lee, Hee Ho Park
Nanoparticles have been extensively used as carriers for the delivery of chemicals and biomolecular drugs, such as anticancer drugs and therapeutic proteins. Natural biomolecules, such as proteins, are an attractive alternative to synthetic polymers commonly used in nanoparticle formulation because of their safety. In general, protein nanoparticles offer many advantages, such as biocompati...... hiện toàn bộ
3D Printing of a Multi-Layered Polypill Containing Six Drugs Using a Novel Stereolithographic Method
Tập 11 Số 6 - Trang 274
Pamela Robles Martinez, Xiaoyan Xu, Sarah J. Trenfield, Atheer Awad, Álvaro Goyanes, Richard Telford, Abdul W. Basit, Simon Gaisford
Three-dimensional printing (3DP) has demonstrated great potential for multi-material fabrication because of its capability for printing bespoke and spatially separated material conformations. Such a concept could revolutionise the pharmaceutical industry, enabling the production of personalised, multi-layered drug products on demand. Here, we developed a novel stereolithographic (SLA) 3D p...... hiện toàn bộ
Polymers for Extrusion-Based 3D Printing of Pharmaceuticals: A Holistic Materials–Process Perspective
Tập 12 Số 2 - Trang 124
Mohammad Azad, Deborah Olawuni, Georgia Kimbell, Abu Zayed Md Badruddoza, Md. Shahadat Hossain, Tasnim Sultana
Three dimensional (3D) printing as an advanced manufacturing technology is progressing to be established in the pharmaceutical industry to overcome the traditional manufacturing regime of 'one size fits for all'. Using 3D printing, it is possible to design and develop complex dosage forms that can be suitable for tuning drug release. Polymers are the key materials that are necessary for 3D...... hiện toàn bộ
The Digital Pharmacies Era: How 3D Printing Technology Using Fused Deposition Modeling Can Become a Reality
Tập 11 Số 3 - Trang 128
Maisa R. P. Araújo, Lívia L. Sá‐Barreto, Taís Gratieri, Guilherme M. Gelfuso, Marcílio Cunha‐Filho
The pharmaceutical industry is set to join the fourth industrial revolution with the 3D printing of medicines. The application of 3D printers in compounding pharmacies will turn them into digital pharmacies, wrapping up the telemedicine care cycle and definitively modifying the pharmacotherapeutic treatment of patients. Fused deposition modeling 3D printing technology melts extruded drug-l...... hiện toàn bộ
Selective Laser Sintering 3D Printing of Orally Disintegrating Printlets Containing Ondansetron
Tập 12 Số 2 - Trang 110
Nour Allahham, Fabrizio Fina, Carmen Marcuta, Lilia Kraschew, Wolfgang Mohr, Simon Gaisford, Abdul W. Basit, Álvaro Goyanes
The aim of this work was to explore the feasibility of using selective laser sintering (SLS) 3D printing (3DP) to fabricate orodispersable printlets (ODPs) containing ondansetron. Ondansetron was first incorporated into drug-cyclodextrin complexes and then combined with the filler mannitol. Two 3D printed formulations with different levels of mannitol were prepared and tested, and a commer...... hiện toàn bộ