Pharmaceutics
SCOPUS (2009-2025)SCIE-ISI
1999-4923
Thụy Sĩ
Cơ quản chủ quản: MDPI , Multidisciplinary Digital Publishing Institute (MDPI)
Lĩnh vực:
Pharmaceutical Science
Phân tích ảnh hưởng
Các bài báo tiêu biểu
Liposomal Formulations in Clinical Use: An Updated Review
Tập 9 Số 2 - Trang 12
Liposomes are the first nano drug delivery systems that have been successfully
translated into real-time clinical applications. These closed bilayer
phospholipid vesicles have witnessed many technical advances in recent years
since their first development in 1965. Delivery of therapeutics by liposomes
alters their biodistribution profile, which further enhances the therapeutic
index of various dru...
An Overview of Chitosan Nanoparticles and Its Application in Non-Parenteral Drug Delivery
Tập 9 Số 4 - Trang 53
The focus of this review is to provide an overview of the chitosan based
nanoparticles for various non-parenteral applications and also to put a
spotlight on current research including sustained release and mucoadhesive
chitosan dosage forms. Chitosan is a biodegradable, biocompatible polymer
regarded as safe for human dietary use and approved for wound dressing
applications. Chitosan has been use...
Transdermal Drug Delivery: Innovative Pharmaceutical Developments Based on Disruption of the Barrier Properties of the Stratum Corneum
Tập 7 Số 4 - Trang 438-470
The skin offers an accessible and convenient site for the administration of
medications. To this end, the field of transdermal drug delivery, aimed at
developing safe and efficacious means of delivering medications across the skin,
has in the past and continues to garner much time and investment with the
continuous advancement of new and innovative approaches. This review details the
progress and ...
Skin Wound Healing Process and New Emerging Technologies for Skin Wound Care and Regeneration
Tập 12 Số 8 - Trang 735
Skin wound healing shows an extraordinary cellular function mechanism, unique in
nature and involving the interaction of several cells, growth factors and
cytokines. Physiological wound healing restores tissue integrity, but in many
cases the process is limited to wound repair. Ongoing studies aim to obtain more
effective wound therapies with the intention of reducing inpatient costs,
providing lo...
Challenges and Recent Progress in Oral Drug Delivery Systems for Biopharmaceuticals
Tập 11 Số 3 - Trang 129
Routes of drug administration and the corresponding physicochemical
characteristics of a given route play significant roles in therapeutic efficacy
and short term/long term biological effects. Each delivery method has favorable
aspects and limitations, each requiring a specific delivery vehicles design.
Among various routes, oral delivery has been recognized as the most attractive
method, mainly d...
Protein-Based Nanoparticles as Drug Delivery Systems
Tập 12 Số 7 - Trang 604
Nanoparticles have been extensively used as carriers for the delivery of
chemicals and biomolecular drugs, such as anticancer drugs and therapeutic
proteins. Natural biomolecules, such as proteins, are an attractive alternative
to synthetic polymers commonly used in nanoparticle formulation because of their
safety. In general, protein nanoparticles offer many advantages, such as
biocompatibility a...
3D Printing of a Multi-Layered Polypill Containing Six Drugs Using a Novel Stereolithographic Method
Tập 11 Số 6 - Trang 274
Three-dimensional printing (3DP) has demonstrated great potential for
multi-material fabrication because of its capability for printing bespoke and
spatially separated material conformations. Such a concept could revolutionise
the pharmaceutical industry, enabling the production of personalised,
multi-layered drug products on demand. Here, we developed a novel
stereolithographic (SLA) 3D printing ...
Polymers for Extrusion-Based 3D Printing of Pharmaceuticals: A Holistic Materials–Process Perspective
Tập 12 Số 2 - Trang 124
Three dimensional (3D) printing as an advanced manufacturing technology is
progressing to be established in the pharmaceutical industry to overcome the
traditional manufacturing regime of 'one size fits for all'. Using 3D printing,
it is possible to design and develop complex dosage forms that can be suitable
for tuning drug release. Polymers are the key materials that are necessary for
3D printin...
The Digital Pharmacies Era: How 3D Printing Technology Using Fused Deposition Modeling Can Become a Reality
Tập 11 Số 3 - Trang 128
The pharmaceutical industry is set to join the fourth industrial revolution with
the 3D printing of medicines. The application of 3D printers in compounding
pharmacies will turn them into digital pharmacies, wrapping up the telemedicine
care cycle and definitively modifying the pharmacotherapeutic treatment of
patients. Fused deposition modeling 3D printing technology melts extruded
drug-loaded fi...
Selective Laser Sintering 3D Printing of Orally Disintegrating Printlets Containing Ondansetron
Tập 12 Số 2 - Trang 110
The aim of this work was to explore the feasibility of using selective laser
sintering (SLS) 3D printing (3DP) to fabricate orodispersable printlets (ODPs)
containing ondansetron. Ondansetron was first incorporated into
drug-cyclodextrin complexes and then combined with the filler mannitol. Two 3D
printed formulations with different levels of mannitol were prepared and tested,
and a commercial ond...