Magnetic Resonance in Medicine

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Changes in water diffusion due to Wallerian degeneration in peripheral nerve
Magnetic Resonance in Medicine - Tập 36 Số 4 - Trang 627-631 - 1996
Christian Beaulieu, Mark D. Does, R. E. Snyder, Peter S. Allen
AbstractThe authors report NMR measurements of the changes in water diffusion brought about by in vivo Wallerian degeneration due to either crush‐ or tie‐injuries in the sciatic nerve of the frog. Using a pulsed‐gradient spin‐echo sequence with a diffusion measurement time of 28 ms, the degree of diffusion coefficient anisotropy {D(longit...... hiện toàn bộ
Toward accurate diagnosis of white matter pathology using diffusion tensor imaging
Magnetic Resonance in Medicine - Tập 57 Số 4 - Trang 688-695 - 2007
Matthew D. Budde, Joong Hee Kim, Hsiao‐Fang Liang, Robert E. Schmidt, John H. Russell, Anne H. Cross, Sheng‐Kwei Song
AbstractDiffusion tensor imaging (DTI) has been widely applied to investigate injuries in the central nervous system (CNS) white matter (WM). However, the underlying pathological correlates of diffusion changes have not been adequately determined. In this study the coregistration of histological sections to MR images and a pixel‐based receiver operating characteris...... hiện toàn bộ
Measurement of the extraction efficiency and distribution volume for Gd‐DTPA in normal and diseased canine myocardium
Magnetic Resonance in Medicine - Tập 30 Số 3 - Trang 337-346 - 1993
Chun Tong, Frank S. Prato, Gerald Wisenberg, Ting Y. Lee, Edwin Carroll, David Sandler, J. M. Wills, Dick Drost
AbstractWe have previously shown that the myocardial Gd‐DTPA concentration ([Gd‐DTPA]t(t)) after a bolus injection of Gd‐DTPA can be predicted by the Modified Kety Equation (MKE). If [Gd‐DTPA]t(t) can be determined by...... hiện toàn bộ
Inversion recovery EPI of bolus transit in rat myocardium using intravascular and extravascular gadolinium‐based MR contrast media: Dose effects on peak signal enhancement
Magnetic Resonance in Medicine - Tập 32 Số 3 - Trang 319-329 - 1994
Michael F. Wendland, Maythem Saeed, K K Yu, Timothy P. L. Roberts, Kirsi Lauerma, Nikita Derugin, John Varadarajan, Alan D. Watson, Charles B. Higgins
AbstractInversion recovery gradient recalled echo planar imaging (TI/TR/TE = 700/2000/10 ms) was used to dynamically monitor the first pass of an intravascular (GdDOTA‐polylysine) and an extravascular (GdDTPA‐BMA) contrast agent through normal rat myocardium. It was found that myocardial enhancement increased wi...... hiện toàn bộ
Practical Implementation and Optimization of One‐shot T1 imaging
Magnetic Resonance in Medicine - Tập 22 Số 2 - Trang 414-424 - 1991
I Kay, R. Mark Henkelman
AbstractLongitudinal relaxation times (T1) can be measured rapidly in an imaging context using a “one‐shot” method based on the pulse sequence originally proposed by D. C. Look and D. R. Locker (Rev. Sci. Instrum. 41, 250 1970). This sequence is significantly faster th...... hiện toàn bộ
In vivo mapping of the fast and slow diffusion tensors in human brain
Magnetic Resonance in Medicine - Tập 47 Số 4 - Trang 623-628 - 2002
Chris A. Clark, Maj Hedehus, Michael E. Moseley
AbstractRecent studies have shown that the diffusional signal decay in human brain is non‐monoexponential and may be described in terms of compartmentalized water fractions. Diffusion tensor imaging (DTI), which provides information about tissue structure and orientation, typically uses b values up to 1000 s mm−2 so t...... hiện toàn bộ
In vivo determination of intra‐myocellular lipids in human muscle by means of localized 1H‐MR‐spectroscopy
Magnetic Resonance in Medicine - Tập 37 Số 4 - Trang 484-493 - 1997
Chris Boesch, Johannes Slotboom, Hans Hoppeler, Roland Kreis
AbstractIntra‐myocellular lipids (IMCL) are stored in droplets in the cytoplasm of muscle cells and are an energy storage form readily accessed during long‐term exercise. 1H‐MR spectroscopy methods are presented for noninvasive determination of IMCL in human muscle. This is based on (a) the separation of two resonances in the lipid‐CH...... hiện toàn bộ
MRI of muscular fat
Magnetic Resonance in Medicine - Tập 47 Số 4 - Trang 720-727 - 2002
Fritz Schick, Jürgen Machann, Klaus Brechtel, Andrea Strempfer, Bernhard Klumpp, Daniel T. Stein, Stephan Jacob
AbstractAn MRI technique with high selectivity and sensitivity to the signal components in the chemical shift range of methylene and methyl protons of fatty acids has been developed for noninvasive assessment of muscular fat in vivo. A spoiled gradient‐echo sequence with spatial‐spectral excitation by six equidistant pulses with 2°‐(−9°)‐17°‐(−17°)‐9°‐(−2°) and a m...... hiện toàn bộ
Quantification of intramyocellular lipids in obese subjects using spectroscopic imaging with high spatial resolution
Magnetic Resonance in Medicine - Tập 57 Số 1 - Trang 22-28 - 2007
Ján Weis, Lars Johansson, Frédéric Courivaud, F. Anders Karlsson, Håkan Åhlström
AbstractQuantification of intramyocellular lipids (IMCL) in obese subjects by single‐voxel spectroscopy (SVS) or conventional spectroscopic imaging (SI) often fails due to overlap of IMCL spectral lines by extramyocellular lipids (EMCL), and signal contamination from subcutaneous fat and bone marrow. This study demonstrates that these problems can be solved by high...... hiện toàn bộ
Shaping the Signal Response during the Approach to Steady State in Three‐Dimensional Magnetization‐Prepared Rapid Gradient‐Echo Imaging Using Variable Flip Angles
Magnetic Resonance in Medicine - Tập 28 Số 2 - Trang 165-185 - 1992
John P. Mugler, Frederick H. Epstein, James R. Brookeman
AbstractA theoretical algorithm for shaping the signal response during the approach to steady state in three‐dimensional magnetization‐prepared rapid gradient‐echo (3D MP‐RAGE) pulse sequences has been developed and implemented. This algorithm derives the flip angle series required to produce specifically chosen time evolutions of the signal intensities during the ...... hiện toàn bộ
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