Magnetic Resonance in Medicine

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Temporally resolved 3D phase‐contrast imaging
Magnetic Resonance in Medicine - Tập 36 Số 5 - Trang 800-803 - 1996
Lars Wigström, Lars Sjöqvist, Bengt Wranne
AbstractA conventional 3D phase contrast acquisition generates images with good spatial resolution, but often gives rise to artifacts due to pulsatile flow. 2D cine phase contrast, on the other hand, can register dynamic flow, but has a poor spatial resolution perpendicular to the imaging plane. A combination of both high spatial and temporal resolution may be adva...... hiện toàn bộ
Detection and modeling of non‐Gaussian apparent diffusion coefficient profiles in human brain data
Magnetic Resonance in Medicine - Tập 48 Số 2 - Trang 331-340 - 2002
Daniel C. Alexander, Gareth J. Barker, Simon Arridge
AbstractThis work details the observation of non‐Gaussian apparent diffusion coefficient (ADC) profiles in multi‐direction, diffusion‐weighted MR data acquired with easily achievable imaging parameters (b≈ 1000 s/mm2). A technique is described for modeling the profile of the ADC over the sphere, which can capture non‐...... hiện toàn bộ
Reduction of eddy‐current‐induced distortion in diffusion MRI using a twice‐refocused spin echo
Magnetic Resonance in Medicine - Tập 49 Số 1 - Trang 177-182 - 2003
Timothy G. Reese, O. Heid, Robert M. Weisskoff, Van J. Wedeen
AbstractImage distortion due to field gradient eddy currents can create image artifacts in diffusion‐weighted MR images. These images, acquired by measuring the attenuation of NMR signal due to directionally dependent diffusion, have recently been shown to be useful in the diagnosis and assessment of acute stroke and in mapping of tissue structure. This work presen...... hiện toàn bộ
The rician distribution of noisy mri data
Magnetic Resonance in Medicine - Tập 34 Số 6 - Trang 910-914 - 1995
Hákon Guðbjartsson, Samuel Patz
AbstractThe image intensity in magnetic resonance magnitude images in the presence of noise is shown to be governed by a Rician distribution. Low signal intensities (SNR < 2) are therefore biased due to the noise. it is shown how the underlying noise can be estimated from the images and a simple correction scheme is provided to reduce the bias. the noise charact...... hiện toàn bộ
Improved Assessment of Significant Activation in Functional Magnetic Resonance Imaging (fMRI): Use of a Cluster‐Size Threshold
Magnetic Resonance in Medicine - Tập 33 Số 5 - Trang 636-647 - 1995
Steven D. Forman, Jonathan D. Cohen, Mark Fitzgerald, William F. Eddy, Mark A. Mintun, Douglas C. Noll
AbstractThe typical functional magnetic resonance (fMRI) study presents a formidable problem of multiple statistical comparisons (i.e, > 10,000 in a 128 x 128 image). To protect against false positives, investigators have typically relied on decreasing the per pixel false positive probability. This approach incurs an inevitable loss of power to detect statistica...... hiện toàn bộ
Role of Increased Cerebral myo‐Inositol in the Dementia of Down Syndrome
Magnetic Resonance in Medicine - Tập 33 Số 6 - Trang 858-861 - 1995
Truda Shonk, Brian D. Ross
AbstractThe purpose of this study was to determine cerebral myo‐inositol (ml) in adults with Down syndrome (DS), and to trace the chronobiology of DS to Alzheimer disease (AD). AD has characteristic neuropathology of neurofibrillary plaques and tangles; indirect evidence links this to earlier deposition of β‐amy...... hiện toàn bộ
NMR relaxation of water in hydrogel polymers: A model for tissue
Magnetic Resonance in Medicine - Tập 9 Số 3 - Trang 325-332 - 1989
John C. Gore, Mark S. Brown, Jianhui Zhong, Karl F. Mueller, William R. Good
AbstractThe NMR relaxation rates ofa class of hydrated polymers (hydrogels) have been investigated over a wide range of frequencies (0.01 to 60 MHz) and compositions. The gels comprise long chains of polytetramethylene oxide diol crosslinked by copolymers of dimethylacrylamide and methylmethacrylate. The longitudinal relaxation rate dispersion curves of these mater...... hiện toàn bộ
Intravoxel incoherent motion imaging using steady‐state free precession
Magnetic Resonance in Medicine - Tập 7 Số 3 - Trang 346-351 - 1988
Denis Le Bihan
AbstractIVIM MR imaging is a method which generates images of diffusion and perfusion in vivo. Until now, intravoxel incoherent motion (IVIM) images have been obtained using spin‐echo sequences with extragradient pulses, resulting in long acquisition times (typically 2 × 8 min 32 s). A new method is proposed here, using steady‐state ... hiện toàn bộ
Effects of intravoxel incoherent motions (IVIM) in steady‐state free precession (SSFP) imaging: application to molecular diffusion imaging
Magnetic Resonance in Medicine - Tập 10 Số 3 - Trang 324-337 - 1989
Denis Le Bihan, Robert Turner, James R. MacFall
AbstractA theoretical analysis of the effects of diffusion and perfusion in steady‐state free precession (SSFP) imaging sequences sensitized to intravoxel incoherent motions by magnetic field gradients is presented and supported by phantom studies. The capability of such sequences to image diffusion and perfusio...... hiện toàn bộ
Measurement of brain perfusion by volume‐localized NMR spectroscopy using inversion of arterial water spins: Accounting for transit time and cross‐relaxation
Magnetic Resonance in Medicine - Tập 25 Số 2 - Trang 362-371 - 1992
Weiguo Zhang, Donald S. Williams, John A. Detre, Alan P. Koretsky
AbstractThe theoretical model for perfusion measurement by NMR using arterial labeling of endogenous water is extended to include the effects of transit time and cross‐relaxation of tissue water with macromolecules. Water magnetization in rat brain is monitored using the STEAM method to simultaneously determine the transit time, magnetization transfer rate constant...... hiện toàn bộ
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