Magnetic Resonance in Medicine

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Changes in water diffusion due to Wallerian degeneration in peripheral nerve
Magnetic Resonance in Medicine - Tập 36 Số 4 - Trang 627-631 - 1996
Christian Beaulieu, Mark D. Does, R. E. Snyder, Peter S. Allen
AbstractThe authors report NMR measurements of the changes in water diffusion brought about by in vivo Wallerian degeneration due to either crush‐ or tie‐injuries in the sciatic nerve of the frog. Using a pulsed‐gradient spin‐echo sequence with a diffusion measurement time of 28 ms, the degree of diffusion coefficient anisotropy {D(longit...... hiện toàn bộ
Toward accurate diagnosis of white matter pathology using diffusion tensor imaging
Magnetic Resonance in Medicine - Tập 57 Số 4 - Trang 688-695 - 2007
Matthew D. Budde, Joong Hee Kim, Hsiao‐Fang Liang, Robert E. Schmidt, John H. Russell, Anne H. Cross, Sheng‐Kwei Song
AbstractDiffusion tensor imaging (DTI) has been widely applied to investigate injuries in the central nervous system (CNS) white matter (WM). However, the underlying pathological correlates of diffusion changes have not been adequately determined. In this study the coregistration of histological sections to MR images and a pixel‐based receiver operating characteris...... hiện toàn bộ
Techniques for the measurement of the local myocardial extraction efficiency for inert diffusible contrast agents such as gadopentate dimeglumine
Magnetic Resonance in Medicine - Tập 30 Số 3 - Trang 332-336 - 1993
Chun Tong, Frank S. Prato, Gerald Wisenberg, Ting Y. Lee, Edwin Carroll, Daivid Sandler, J. M. Wills
AbstractWe have previously shown that the concentration of Gd‐DTPA as, a function of time ([Gd‐DTPA]t(t)) in the myocardium following an intravenous bolus injection of Gd‐DTPA can be moldered using the Modified Kety Equation. Fitting this model to measurements of [Gd‐DTPA]... hiện toàn bộ
MRI detection of myocardial perfusion changes by gadolinium‐DTPA infusion during dipyridamole hyperemia
Magnetic Resonance in Medicine - Tập 10 Số 2 - Trang 246-255 - 1989
D. Douglas Miller, Godtfred Holmvang, John B. Gill, Donna Dragotakes, Howard L. Kantor, Robert D. Okada, Thomas J. Brady
AbstractTo detect abnormal regional myocardial coronary flow reserve, serial spin‐echo MR tomograms of four control dogs and six with a partial balloon occlusion of the left anterior descending (LAD) coronary artery were acquired before and after dipyridamole infusion and during the paramagnetic effect of a bolus plus infusion of gadolinium‐DTPA. Microsphere myocar...... hiện toàn bộ
Measurement of the extraction efficiency and distribution volume for Gd‐DTPA in normal and diseased canine myocardium
Magnetic Resonance in Medicine - Tập 30 Số 3 - Trang 337-346 - 1993
Chun Tong, Frank S. Prato, Gerald Wisenberg, Ting Y. Lee, Edwin Carroll, David Sandler, J. M. Wills, Dick Drost
AbstractWe have previously shown that the myocardial Gd‐DTPA concentration ([Gd‐DTPA]t(t)) after a bolus injection of Gd‐DTPA can be predicted by the Modified Kety Equation (MKE). If [Gd‐DTPA]t(t) can be determined by...... hiện toàn bộ
Practical Implementation and Optimization of One‐shot T1 imaging
Magnetic Resonance in Medicine - Tập 22 Số 2 - Trang 414-424 - 1991
I Kay, R. Mark Henkelman
AbstractLongitudinal relaxation times (T1) can be measured rapidly in an imaging context using a “one‐shot” method based on the pulse sequence originally proposed by D. C. Look and D. R. Locker (Rev. Sci. Instrum. 41, 250 1970). This sequence is significantly faster th...... hiện toàn bộ
Inversion recovery EPI of bolus transit in rat myocardium using intravascular and extravascular gadolinium‐based MR contrast media: Dose effects on peak signal enhancement
Magnetic Resonance in Medicine - Tập 32 Số 3 - Trang 319-329 - 1994
Michael F. Wendland, Maythem Saeed, K K Yu, Timothy P. L. Roberts, Kirsi Lauerma, Nikita Derugin, John Varadarajan, Alan D. Watson, Charles B. Higgins
AbstractInversion recovery gradient recalled echo planar imaging (TI/TR/TE = 700/2000/10 ms) was used to dynamically monitor the first pass of an intravascular (GdDOTA‐polylysine) and an extravascular (GdDTPA‐BMA) contrast agent through normal rat myocardium. It was found that myocardial enhancement increased wi...... hiện toàn bộ
In vivo mapping of the fast and slow diffusion tensors in human brain
Magnetic Resonance in Medicine - Tập 47 Số 4 - Trang 623-628 - 2002
Chris A. Clark, Maj Hedehus, Michael E. Moseley
AbstractRecent studies have shown that the diffusional signal decay in human brain is non‐monoexponential and may be described in terms of compartmentalized water fractions. Diffusion tensor imaging (DTI), which provides information about tissue structure and orientation, typically uses b values up to 1000 s mm−2 so t...... hiện toàn bộ
Analysis and generalized correction of the effect of spatial gradient field distortions in diffusion‐weighted imaging
Magnetic Resonance in Medicine - Tập 50 Số 3 - Trang 560-569 - 2003
Roland Bammer, Michael Markl, Alan Barnett, Burak Acar, Marcus T. Alley, Norbert J. Pelc, Gary H. Glover, Michael E. Moseley
AbstractNonuniformities of magnetic field gradients can cause serious artifacts in diffusion imaging. While it is well known that nonlinearities of the imaging gradients lead to image warping, those imperfections can also cause spatially dependent errors in the direction and magnitude of the diffusion encoding. This study shows that the potential errors in diffusio...... hiện toàn bộ
In vivo measurement and imaging of tumor oxygenation using coembedded paramagnetic particulates
Magnetic Resonance in Medicine - Tập 52 Số 3 - Trang 650-657 - 2004
Govindasamy Ilangovan, Anna Bratasz, Haiquan Li, Petra Schmalbrock, Jay L. Zweíer, Periannan Kuppusamy
AbstractTumor tissue oxygenation is an important parameter that is positively correlated to the chemo‐ or radiation treatment outcome of certain tumors. Hence, methods to accurately and noninvasively determine the concentration of oxygen (pO2) in tumors will be valuable. In this study, electron paramagnetic resonance (EPR) spectroscopy, utilizi...... hiện toàn bộ
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