Practical Implementation and Optimization of One‐shot T1 imaging

Magnetic Resonance in Medicine - Tập 22 Số 2 - Trang 414-424 - 1991
I Kay1, R. Mark Henkelman2
1Department of Medical Biophysics, University of Toronto, Ontario, Canada
2Department of Medical Biophysics, University of Toronto, and Sunnybrook Health Science Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada M4N 3M5

Tóm tắt

AbstractLongitudinal relaxation times (T1) can be measured rapidly in an imaging context using a “one‐shot” method based on the pulse sequence originally proposed by D. C. Look and D. R. Locker (Rev. Sci. Instrum. 41, 250 1970). This sequence is significantly faster than either repeated inversion recovery or repeated saturation recovery methods. The method uses a 180° inversion pulse followed by multiple small‐angle α pulses that sample the longitudinal magnetization during its recovery. Choices of inversion pulse, tip angle, and time intervals are discussed for optimal clinical use. We can produce 29 images sampling the full T1 recovery curve with a 256 × 256 resolution in about 10 min. From this data, T1 images can be calculated with a precision of 10%. © 1991 Academic Press, Inc.

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