Journal of Oral Pathology and Medicine
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Resveratrol suppresses TPA ‐induced matrix metalloproteinase‐9 expression through the inhibition of MAPK pathways in oral cancer cells
Journal of Oral Pathology and Medicine - Tập 44 Số 9 - Trang 699-706 - 2015
BackgroundNaturally occurring agents, such as resveratrol, have been determined
to benefit health. Numerous studies have demonstrated that resveratrol has
antioxidative, cardioprotective, and neuroprotective properties. However, the
effect of resveratrol exerts on the metastasis of oral cancer cells remains
unclear. In this study, we investigated the effect the anti‐invasive activity of
resveratro...
Dysregulated expression of bcl‐2 and bax in oral carcinomas: evidence of post‐transcriptional control
Journal of Oral Pathology and Medicine - Tập 29 Số 2 - Trang 63-69 - 2000
Abstract: A study was conducted to investigate the gene expression of bcl‐2 and
bax in oral squamous cell carcinomas. We used reverse–transcriptase‐polymerase
chain reacion (RT–PCR) to evaluate the expression of bcl‐2 and bax mRNAs and the
ratio of bcl‐2/bax mRNA, and employed immunohistochemistry to investigate the
bcl‐2‐ and bax‐encoded proteins. It was observed that the expression level of
bcl‐...
Progress in determining the malignant potential of oral lesions
Journal of Oral Pathology and Medicine - Tập 32 Số 5 - Trang 251-256 - 2003
AbstractThe dilemma in managing patients with potentially malignant oral lesions
and field change is of deciding which mucosal lesions or areas will progress to
carcinoma. Although dysplasia may be predictive, this is not invariable, and
there can be considerable inter‐ and intraexaminer variation in that diagnosis.
Recent data on molecular and DNA changes in potentially malignant lesions
suggest ...
Detection of C andida albicans ADH1 and ADH2 mRNA s in human archival oral biopsy samples
Journal of Oral Pathology and Medicine - Tập 43 Số 9 - Trang 704-710 - 2014
ObjectivesThe aim of this study was to investigate the relationship between
expression of Candida albicans alcohol dehydrogenases (ADH) genes in archival
formalin‐fixed paraffin‐embedded (FFPE) samples from biopsies of
leukoplakia.Materials and MethodsArchival FFPE samples were obtained from four
sample groups: normal oral mucosa, non‐dysplastic leukoplakia, chronic
hyperplastic candidosis (CHC), ...
Oral squamous cell carcinoma grading systems – analysis of the best survival predictor
Journal of Oral Pathology and Medicine - Tập 41 Số 1 - Trang 34-39 - 2012
J Oral Pathol Med (2012) 41: 34–39Background: The TNM system has been used for
decades in an attempt to predict clinical behavior and appropriate therapy for
oral squamous cell carcinomas. Histopathologic classifications can be useful as
an additional predictive tool. The purpose of this study was to apply four
grading systems (Multiparameter Grading System, Malignancy Grading of the Deep
Invasiv...
Stem cell patterns in cell lines derived from head and neck squamous cell carcinoma
Journal of Oral Pathology and Medicine - Tập 36 Số 10 - Trang 594-603 - 2007
The initiation, growth, recurrence and metastasis of solid tumours, including
squamous cell carcinoma of the head and neck region, have been related to the
behaviour of a small subpopulation of ‘tumour‐initiating’ cells. Cells with stem
cell characteristics have also been identified in cell lines derived from
cancers and the aim of the present work was to extend examination of such cells.
Establis...
Pathological characteristics metastatic carcinoma in the human mandible
Journal of Oral Pathology and Medicine - Tập 16 Số 7 - Trang 362-367 - 1987
Based on the large celloidin‐embedded section method, human mandibles from 62
autopsied carcinoma cases were examined histologically to determine the
pathological characteristics of any mandibular metaslases. Metastasis was
confirmed histologically in 10 (16%) of the 62 cases and was comparatively
frequent with gastric and pulmonary carcinomas. The hemopoietic areas in the
mandibular marrow seemed...
Betel quid chewing, cigarette smoking and alcohol consumption related to oral cancer in Taiwan
Journal of Oral Pathology and Medicine - Tập 24 Số 10 - Trang 450-453 - 1995
A hospital‐based case‐control study of matched pairs was conducted to explore
(a) the relationship between the use of betel quid chewing, cigarette smoking,
alcohol drinking and oral cancer and (b) synergism between these factors. The
case group consisted of 104 male and 3 female oral cancer patients and these
were compared with 194 male and 6 female matched controls. We found by
univariate analys...
Fine‐needle aspiration cytology: a reliable tool in the diagnosis of salivary gland lesions
Journal of Oral Pathology and Medicine - Tập 41 Số 1 - Trang 106-112 - 2012
J Oral Pathol Med (2012) 41: 106–112Background: Fine‐needle aspiration cytology
(FNAC) is used as the main initial diagnostic investigation for lumps in the
head and neck region. Major salivary glands and some minor salivary glands are
easily accessible; therefore, they are optimal targets for FNAC. The aim of this
study was to discuss the advantages and pitfalls of FNAC as compared to
histopatho...
Clinicopathological evaluation of carcinoma cuniculatum: a variant of oral squamous cell carcinoma
Journal of Oral Pathology and Medicine - Tập 41 Số 4 - Trang 303-308 - 2012
J Oral Pathol Med (2012) 41: 303–308Carcinoma cuniculatum (CC) is a rare
neoplasm of oral squamous cell carcinoma (OSCC) and remains a histopathological
challenge to pathologists because of its low incidence and unique architecture.
Therefore, the purpose of this study was to illustrate the clinicopathological
findings and biological behavior about this distinctive lesion. Clinical and
follow‐up i...
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