Fine‐needle aspiration cytology: a reliable tool in the diagnosis of salivary gland lesions

Journal of Oral Pathology and Medicine - Tập 41 Số 1 - Trang 106-112 - 2012
Kanwar Deep Singh Nanda1, Anurag Mehta2, Jasmine Nanda3
1Department of Oral and Maxillofacial Pathology, SGT Dental College, Gurgaon, India
2Department of Pathology, Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India
3Department of Pedodontics, ITS dental college, Uttar Pradesh, India

Tóm tắt

J Oral Pathol Med (2012) 41: 106–112Background:  Fine‐needle aspiration cytology (FNAC) is used as the main initial diagnostic investigation for lumps in the head and neck region. Major salivary glands and some minor salivary glands are easily accessible; therefore, they are optimal targets for FNAC. The aim of this study was to discuss the advantages and pitfalls of FNAC as compared to histopathology in the salivary gland lesions.Material and methods:  A total of 127 FNAC were carried out on salivary gland lesions from January 2006 to December 2010 – a 5‐year period. Histopathological follow‐up data were obtained in 56 cases. The study was conducted to examine the sensitivity, specificity, and accuracy of FNAC for salivary gland swellings in comparison with histopathology.Results:  The male‐to‐female ratio was 2.4:1. Parotid gland was involved in 51.1%, submandibular gland in 37%, sublingual gland in 4.7%, and minor salivary glands in 7% of patients. There were 55.9% cases of non‐neoplastic lesions and 44.1% cases of neoplastic lesions on biopsy. Sensitivity, specificity, positive predictive value, and negative predictive value of FNAC for malignant neoplastic lesions were 84.61%, 86.48%, 68.75%, and 94.11%, respectively, whereas for benign neoplastic lesions, they were 84.61%, 91.66%, 91.6%, and 85%, respectively.Conclusion:  Fine‐needle aspiration cytology is found to be a good sensitive and specific technique for the diagnosis of most of the salivary gland lesions. FNAC should be adopted as an initial investigation for all salivary gland swellings in conjunction with other investigations where appropriate.

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Journal of Oral Pathology and Medicine

Tập 41 Số 1

106-112

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