Betel quid chewing, cigarette smoking and alcohol consumption related to oral cancer in Taiwan

Journal of Oral Pathology and Medicine - Tập 24 Số 10 - Trang 450-453 - 1995
Ying‐Chin Ko1, Yeou‐Lih Huang2, Chien‐Hung Lee1, M C Chen1, Li‐Min Lin2, Chih‐Cheng Tsai2
1School of Public Health, Kaohsiung Medical College, Taiwan, Repulic of China
2School of Dentistry, Kaohsiung Medical College, Taiwan, Repulic of China

Tóm tắt

A hospital‐based case‐control study of matched pairs was conducted to explore (a) the relationship between the use of betel quid chewing, cigarette smoking, alcohol drinking and oral cancer and (b) synergism between these factors. The case group consisted of 104 male and 3 female oral cancer patients and these were compared with 194 male and 6 female matched controls. We found by univariate analysis that alcohol consumption, smoking, betel quid chewing, educational level and occupation were associated with oral cancer. The adjusted odds ratios were to be found elevated in patients who were smoking and betel quid chewing. After adjusting for education and occupation covariates, the incidence of oral cancer was computed to be 123‐fold higher in patients who smoked, drank alcohol and chewed betel quid than in obstainers. The synergistic effects of alcohol, tobacco smoke and betel quid in oral cancer were clearly demonstrated, but there was a statistically significant association between oral cancer and betel quid chewing alone. Swallowing betel quid juice (saliva extract of betel quid produced by chewing) or including unripened betel fruit in the quid both seemed to enhance the risks of contracting oral cancer.

Từ khóa


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Thông tin
Thông tin xuất bản

Journal of Oral Pathology and Medicine

Tập 24 Số 10

450-453

Thông tin tác giả