Pathological characteristics metastatic carcinoma in the human mandible

Journal of Oral Pathology and Medicine - Tập 16 Số 7 - Trang 362-367 - 1987
Nobuhiro Hashimoto1, Kenji Kurihara2, Hideo Yamasaki3, Seigo Ohba2, Sakai Hiroatsu2, Shoko Yoshida2
1Department of Oral Pathology, Kyushu University, Fukuoka, Japan
2Department of Oral Pathology, Fukuoka University Hospital, Fukuoka, Japan.
3Department of Oral Surgery Kyushu University and Fukuoka University Hospital, Fukuoka, Japan.

Tóm tắt

Based on the large celloidin‐embedded section method, human mandibles from 62 autopsied carcinoma cases were examined histologically to determine the pathological characteristics of any mandibular metaslases. Metastasis was confirmed histologically in 10 (16%) of the 62 cases and was comparatively frequent with gastric and pulmonary carcinomas. The hemopoietic areas in the mandibular marrow seemed to favor the early deposition of tumor cells. These micrometastatic foci seemed to increase in size, spreading to all parts, including the periodontal tissue or anterior part of the mandibular body. Increased hemopoietic activity following lodgement, seemed to play an important role for further metastases. Roentogenographic examination did not seem to be the best method of detecting metastasis.

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