Journal of International Medical Research
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MicroRNA-486-5p improves nonsmall-cell lung cancer chemotherapy sensitivity and inhibits epithelial–mesenchymal transition by targeting twinfilin actin binding protein 1
Journal of International Medical Research - Tập 47 Số 8 - Trang 3745-3756 - 2019
ObjectiveTo investigate the role of microRNA-486-5p (miR-486-5p) in
nonsmall-cell lung cancer (NSCLC) resistance to cisplatin.MethodsThis
retrospective study examined tumours and normal lung tissues from patients with
NSCLC. The levels of miR-486-5p in NSCLC and normal tissues were determined
using reverse transcription–polymerase chain reaction. The binding site of
miR-486-5p on twinfilin actin b...
Brucella-induced thrombocytopenia: a retrospective study of 16 patients
Journal of International Medical Research - Tập 47 Số 7 - Trang 3008-3013 - 2019
Objective We aimed to describe the clinical characteristics and treatment
outcomes of 16 patients with Brucella-induced thrombocytopenia. Methods We
assessed 16 patients with Brucella-induced thrombocytopenia between 2012 and
2016 in The First Affiliated Hospital of Xinjiang Medical University. The
diagnosis of Brucella-induced thrombocytopenia was ≤100,000 platelets/mm3.
Results All patients were...
Intravenous transfusion of iron sucrose reduces blood transfusions and improves postoperative anaemia after a second thoracotomy: a propensity-score matching study
Journal of International Medical Research - Tập 48 Số 2 - Trang 030006052090291 - 2020
Tác động của các kỹ thuật chuẩn bị tinh trùng tới khả năng sống sót và phân mảnh DNA của tinh trùng Dịch bởi AI
Journal of International Medical Research - Tập 50 Số 5 - 2022
Mục tiêuNghiên cứu này được thực hiện để xác định tác động của phương pháp bơi
lên (SU) và ly tâm độ đặc (DGC) đối với sự sống sót của tinh trùng và phân mảnh
DNA.Phương phápCác mẫu tinh dịch riêng lẻ được phân tích trước khi mỗi mẫu được
chia thành hai phần (nửa cho SU và nửa cho DGC) để tính toán sự sống sót của
tinh trùng và chỉ số phân mảnh DNA (DFI). Phân mảnh DNA của tinh trùng được xác
định...
Intravenous Lidocaine for Effective Pain Relief after Inguinal Herniorrhaphy: A Prospective, Randomized, Double-Blind, Placebo-Controlled Study
Journal of International Medical Research - Tập 39 Số 2 - Trang 435-445 - 2011
This prospective, randomized, double-blind, placebo-controlled study evaluated
the effectiveness of intravenous lidocaine to reduce post-operative pain in 64
inguinal herniorrhaphy patients. Intravenous bolus injection of 1.5 mg/kg
lidocaine followed by a continuous lidocaine infusion of 2 mg/kg per h was
randomly assigned to 32 patients (lidocaine group) and intravenous normal saline
bolus inject...
Physiologic and hemodynamic changes in patients undergoing open abdominal cytoreductive surgery with hyperthermic intraperitoneal chemotherapy
Journal of International Medical Research - Tập 49 Số 1 - Trang 030006052098326 - 2021
Objective We aimed to determine the physiological and hemodynamic changes in
patients who were undergoing hyperthermic intraperitoneal chemotherapy (HIPEC)
cytoreductive surgeries. Methods This prospective, observational study enrolled
21 patients who were undergoing elective cytoreductive surgery with HIPEC at our
hospital over 2 years. We collected vital signs, hemodynamic parameters
including g...
Effects of High-monounsaturated Fatty Acid Enteral Formula versus High-carbohydrate Enteral Formula on Plasma Glucose Concentration and Insulin Secretion in Healthy Individuals and Diabetic Patients
Journal of International Medical Research - Tập 36 Số 1 - Trang 137-146 - 2008
We investigated the effects of high-monounsaturated fatty acid (MUFA) versus
high-carbohydrate enteral formula on post-prandial plasma glucose concentration
and insulin response in Japanese patients with type 2 diabetes mellitus and
healthy Japanese volunteers. Ten healthy volunteers aged 20.8 ± 1.2 years and 12
diabetic patients with good glycaemic control (glycosylated haemoglobulin < 7%)
aged 5...
YKL-40 Protein Levels and Clinical Outcome of Human Endometrial Cancer
Journal of International Medical Research - Tập 38 Số 4 - Trang 1448-1457 - 2010
The secreted glycoprotein YKL-40 is a member of the chitinase family and
elevated serum YKL-40 levels have been reported to be associated with reduced
survival in several malignancies, including endometrial cancer. This study
investigated immunoreactivity to YKL-40 protein and its prognostic implications
in endometrial cancer. Levels of YKL-40 protein in normal endometrium ( n = 42),
endometrial h...
Efficacy and safety of a modified method for blind bedside placement of post-pyloric feeding tube: a prospective preliminary clinical trial
Journal of International Medical Research - Tập 49 Số 2 - 2021
Objective To compare the efficacy and safety of a new modified method of bedside
post-pyloric feeding tube catheterization with the Corpak protocol versus
electromagnetic-guided catheterization. Materials and Methods We conducted a
single-center, single-blinded, prospective clinical trial. Sixty-three patients
were treated with a non-gravity type gastrointestinal feeding tube using
different proce...
Atrial Fibrillation after Off-pump Coronary Artery Surgery: A Prospective, Matched Study
Journal of International Medical Research - Tập 35 Số 1 - Trang 134-142 - 2007
The effect of cardiopulmonary bypass and myocardial ischaemia on the occurrence
of atrial fibrillation (AF) after coronary artery bypass graft (CABG) was
studied in 136 patients undergoing off-pump CABG who were matched for age and
number of distal anastomoses with 136 patients undergoing on-pump CABG. Possible
risk factors for postoperative new-onset AF were recorded. AF occurred in 64
(24%) of t...
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