Frontiers in Chemistry
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Organic electrochromic energy storage materials and device design While not affecting electrochemical performance of energy storage devices, integrating multi-functional properties such as electrochromic functions into energy storage devices can effectively promote the development of multifunctional devices. Compared with inorganic electrochromic materials, organic materials possess the significant advantages of facile preparation, low cost, and large color contrast. Specifically, most polymer materials show excellent electrochemical properties, which can be widely used in the design and development of energy storage devices. In this article, we focus on the application of organic electrochromic materials in energy storage devices. The working mechanisms, electrochemical performance of different types of organics as well as the shortcomings of organic electrochromic materials in related devices are discussed in detail.
Frontiers in Chemistry - Tập 10
Editorial: Functionalized Inorganic Semiconductor Nanomaterials: Characterization, Properties, and Applications
Frontiers in Chemistry - Tập 8
Photocatalytic Activation of Saturated C–H Bond Over the CdS Mixed-Phase Under Visible Light Irradiation
Frontiers in Chemistry - Tập 6
Porous Alumina Membrane-Based Electrochemical Biosensor for Protein Biomarker Detection in Chronic Wounds
Frontiers in Chemistry - Tập 8
Nanoparticle Formulations of Poly (ADP-ribose) Polymerase Inhibitors for Cancer Therapy A number of poly(ADP-ribose) polymerase (PARP) inhibitors have been recently approved for clinical use in BRCA mutated and other cancers. However, off-target toxicity of PARP inhibitors and the emergence of drug resistance following prolonged administration of these inhibitors indicate the need for improved methods of drug delivery to the tumors. Nanomedicines based upon nanoparticle formulations of conventional small molecule drugs and inhibitors offer many advantages, such as increased solubility and bioavailability of drugs, reduced toxicity and drug resistance, and improved tissue selectivity and therapeutic efficacy. This review highlights the current trends in formulations of PARP inhibitors developed by nanotechnology approaches and provides an insight into the applications and limitations of these PARP inhibitor nanomedicines for cancer therapies.
Frontiers in Chemistry - Tập 8
Novel Strategies in C-H Oxidations for Natural Product Diversification—A Remote Functionalization Application Summary Selectively activating the distal inactive C-H bond for functionalization is one of the on-going challenge in organic synthetic chemistry. In recent years, benefiting from the development of selective synthesis methods, novel methodologies not only make it possible to break non-traditional chemical bonds and attain more diversity in inactive sites, but also provide more possibilities for the diversification of complex natural products. Direct C-H bond functionalization approaches make it feasible to explore structure-activity relationship (SAR), generate metabolites and derivatives, and prepare biological probes. Among them, direct oxidation of inert C-H bonds is one of the most common methods for natural product diversification. In this review, we focus on the application of remote functionalization of inert C-H bonds for natural products derivatization, including the establishment of oxidation methods, the regulation of reaction sites, and the biological activities of derivatives. We highlight the challenges and opportunities of remote functionalization of inert C-H bonds for natural product diversification through selected and representative examples. We try to show that inert C-H bond oxidation, properly regulated and optimized, can be a powerful and efficient strategy in both synthetic and medicinal chemistry.
Frontiers in Chemistry - Tập 9
Decavanadate Salts of Cytosine and Metformin: A Combined Experimental-Theoretical Study of Potential Metallodrugs Against Diabetes and Cancer
Frontiers in Chemistry - Tập 6
In silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization
Frontiers in Chemistry - Tập 8
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