Modeling the Kinetics, Curing Depth, and Efficacy of Radical-Mediated Photopolymerization: The Role of Oxygen Inhibition, Viscosity, and Dynamic Light Intensity

Jui‐Teng Lin1, Hsia‐Wei Liu2, Kuo‐Ti Chen3, Da‐Chuan Cheng4
1New Vision, Inc., Taipei City, Taiwan
2Department of Life Science, Fu Jen Catholic University, New Taipei City, Taiwan
3Graduate Institute of Applied Science and Engineering, Fu Jen Catholic University, New Taipei City, Taiwan
4Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan

Tóm tắt

Từ khóa


Tài liệu tham khảo

Alvankarian, 2015, Exploiting the oxygen inhibitory effect on UV curing in microfabrication: a modified lithography technique, PLoS ONE, 10, e0119658, 10.1371/journal.pone.0119658

Cabral, 2004, Frontal photopolymerization for microfluidic applications, Langmuir, 20, 10020, 10.1021/la049501e

Chen, 2017, Synthesis of micropillar arrays via photopolymerization: an in situ study of light-induced formation, growth kinetics, and the influence of oxygen inhibition, Macromolecules, 50, 5767, 10.1021/acs.macromol.7b01274

Chen, 2014, Principles of Tissue Engineering, 4th Edn.

Chen, , Thiol-ene photopolymerization in thick polymers: kinetics and analytic formulas for the efficacy and crosslink depth, Polymers, 11, 1640, 10.3390/polym11101640

Chen, , Enhancing radical-mediated photopylomerization efficacy and crosslink depth: kinetic and model of a two-monomer system, Res. Med. Eng. Sci, 8, 853, 10.31031/RMES.2019.08.000682

Childress, 2019, Independent control of singlet oxygen and radical generation via Irradiation of a two-color photosensitive molecule, Macromolecules, 52, 4968, 10.1021/acs.macromol.9b00424

Claudino, 2016, Mechanistic kinetic modeling of Thiol-Michael addition photopolymerizations via photocaged “superbase” generators: an analytical approach, Macromolecules, 49, 8061, 10.1021/acs.macromol.6b01605

Cramer, 2008, Mechanisms, polymerization rate scaling, and oxygen inhibition with an ultra-rapid monovinyl urethane acrylate, Polymer, 49, 4756, 10.1016/j.polymer.2008.08.051

Dendukuri, 2008, Modeling of oxygen-inhibited free radical photopolymerization in a PDMS microfluidic device, Macromolecules, 41, 8547, 10.1021/ma801219w

Fouassier, 1995, Photoinitiation, Photo-Polymerization, and Photocuring: Fundamentals and Applications; Hanser Gardner Publications

Kotisch, 2017, Photocontrolled interconversion of cationic and radical polymerizations, J. Am. Chem. Soc., 139, 10665, 10.1021/jacs.7b06661

Lin, 2018, Efficacy S-formula and kinetics of oxygen-mediated (type-II) and non-oxygen-mediated (type-I) corneal cross-linking, Ophthalmol. Res, 8, 1, 10.9734/OR/2018/39089

Lin, 2019, Kinetics of enhancer-monomer for corneal cross-linking: two-initiator system, Ophthalmol. Res, 10, 1, 10.9734/or/2019/v10i330109

Lin, 2017, Modeling the efficacy profiles of UV-light activated corneal collagen crosslinking, PLoS ONE, 12, e0175002, 10.1371/journal.pone.0175002

Lin, 2019, Modeling the optimal conditions for improved efficacy and crosslink depth of photo-initiated polymerization, Polymers, 11, 217, 10.3390/polym11020217

Lin, 2016, Analytic formulas and numerical simulations for the dynamics of thick and non-uniform polymerization by a UV light, J. Polym. Res, 23, 53, 10.1007/s10965-016-0934-4

O'Brien, 2006, Modeling the effect of oxygen on photopolymerization kinetics, Macromol. Theory Simul, 15, 176, 10.1021/ma051863l

Odian, 2006, Principles of Polymerization, 4th Edn

Semchishen, 2015, Model for optimization of the UV-A/Riboflavin strengthening (cross-linking) of the cornea: percolation threshold, Photochem. Photobiol., 91, 1403, 10.1111/php.12498

Wertheimer, 2019, Enhancing rose Bengal photosensitized protein crosslinking in the cornea, Invest. Ophthalmol. Vis. Sci, 60, 1845, 10.1167/iovs.19-26604

Wohlers, 2016, 3D Printing and Additive Manufacturing State of the Industry

Wu, 2018, Evolution of material properties during free radical photopolymerization, J. Mech. Phys. Solid, 112, 25, 10.1016/j.jmps.2017.11.018

Yang, 2018, Progress in photo-responsive polypeptide derived nano-assemblies, Micromachines, 9, 296, 10.3390/mi9060296